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Changing landscape of optical imaging in skeletal metastases.
Cho N, Shokeen M. Cho N, et al. J Bone Oncol. 2019 Jun 27;17:100249. doi: 10.1016/j.jbo.2019.100249. eCollection 2019 Aug. J Bone Oncol. 2019. PMID: 31316892 Free PMC article. Review.
Optical imaging is an emerging strategy for in vitro and in vivo visualization of the molecular mechanisms of cancer over time. An increasing number of optical imaging contrast agents and techniques have been developed in recent years specifically for bone research and ske …
Optical imaging is an emerging strategy for in vitro and in vivo visualization of the molecular mechanisms of cancer over time. An in …
Development of New CD38 Targeted Peptides for Cancer Imaging.
Zheleznyak A, Tang R, Duncan K, Manion B, Liang K, Xu B, Vanover A, Ghai A, Prior J, Lees S, Achilefu S, Kelly K, Shokeen M. Zheleznyak A, et al. Mol Imaging Biol. 2024 Mar 13. doi: 10.1007/s11307-024-01901-5. Online ahead of print. Mol Imaging Biol. 2024. PMID: 38480650
Furthermore, our new CD38-targeted radiopharmaceutical allowed visualization of tumors located in marrow rich bones, remaining there for up to 4 h. ...CONCLUSIONS: The novel CD38-targeted, radiolabeled bioconjugates were specific and allowed visualization of MM, pro …
Furthermore, our new CD38-targeted radiopharmaceutical allowed visualization of tumors located in marrow rich bones, remaining there …
Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma.
Cho N, Ko S, Shokeen M. Cho N, et al. Oncotarget. 2021 Sep 28;12(20):2039-2050. doi: 10.18632/oncotarget.28074. eCollection 2021 Sep 28. Oncotarget. 2021. PMID: 34611478 Free PMC article.
We demonstrated the conjugation of: 1) DM1 enhanced tumor-killing efficacy of the native DARA and 2) IRDye800 allowed for visualization of uptake and tumor targeting ability of the ADC. With the advent of other classes of immunoconjugates for use in MM, we reasoned that su …
We demonstrated the conjugation of: 1) DM1 enhanced tumor-killing efficacy of the native DARA and 2) IRDye800 allowed for visualization …
Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche.
Shokeen M, Zheleznyak A, Wilson JM, Jiang M, Liu R, Ferdani R, Lam KS, Schwarz JK, Anderson CJ. Shokeen M, et al. J Nucl Med. 2012 May;53(5):779-86. doi: 10.2967/jnumed.111.100073. Epub 2012 Apr 10. J Nucl Med. 2012. PMID: 22496586 Free PMC article.
CONCLUSION: The results of the study demonstrated the potential of PET with VLA-4-targeted (64)Cu-CB-TE2A-LLP2A to visualize BMD cell reorganization and expansion noninvasively in vivo....
CONCLUSION: The results of the study demonstrated the potential of PET with VLA-4-targeted (64)Cu-CB-TE2A-LLP2A to visualize BMD cell …