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Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy.
Boetker JP, Savolainen M, Koradia V, Tian F, Rades T, Müllertz A, Cornett C, Rantanen J, Østergaard J. Boetker JP, et al. Mol Pharm. 2011 Aug 1;8(4):1372-80. doi: 10.1021/mp200205z. Epub 2011 Jun 20. Mol Pharm. 2011. PMID: 21634435
The UV imaging instrumentation offers recording of absorbance maps with a high spatial and temporal resolution which facilitates the abundant collection of information regarding the evolving solution concentrations. In this study, UV imaging was used to visualize the disso …
The UV imaging instrumentation offers recording of absorbance maps with a high spatial and temporal resolution which facilitates the abundan …
Integrated approach to study the dehydration kinetics of nitrofurantoin monohydrate.
Koradia V, de Diego HL, Elema MR, Rantanen J. Koradia V, et al. J Pharm Sci. 2010 Sep;99(9):3966-76. doi: 10.1002/jps.22244. J Pharm Sci. 2010. PMID: 20575054
Model-fitting analysis indicated a good fit for several models derived from nucleation-growth and/or geometric contraction mechanisms. However, based on visual observations during HSM, Avrami-Erofeyev equations A3 and A4, indicating nucleation-growth phenomenon, were found …
Model-fitting analysis indicated a good fit for several models derived from nucleation-growth and/or geometric contraction mechanisms. Howev …