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Investigation of laser-induced choroidal neovascularization in the rat.
Semkova I, Peters S, Welsandt G, Janicki H, Jordan J, Schraermeyer U. Semkova I, et al. Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5349-54. doi: 10.1167/iovs.02-0732. Invest Ophthalmol Vis Sci. 2003. PMID: 14638737
Cross-sections demonstrated that these vessels originated from the retina. The center of the scars contained homogenous endothelial cells of choroidal origin, which was confirmed by immunohistochemistry and electron microscopy. ...CONCLUSIONS: In the rat model of laser-ind …
Cross-sections demonstrated that these vessels originated from the retina. The center of the scars contained homogenous endothelial c …
Anti-angiogenic effect of the basement membrane protein nidogen-1 in a mouse model of choroidal neovascularization.
Semkova I, Kociok N, Karagiannis D, Nischt R, Smyth N, Paulsson M, Strauß O, Joussen AM. Semkova I, et al. Exp Eye Res. 2014 Jan;118:80-8. doi: 10.1016/j.exer.2013.11.006. Epub 2013 Nov 23. Exp Eye Res. 2014. PMID: 24280453
In the retina the absence of nidogen-1 does not influence the expression of nidogen-2 and vice versa and does not influence the expression of the BM components collagen IV, laminin gamma1, and perlecan. In Nid1(-/-) mice, CNV lesions showed increased vessel leakage during …
In the retina the absence of nidogen-1 does not influence the expression of nidogen-2 and vice versa and does not influence the expression o …
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations.
Joussen AM, Doehmen S, Le ML, Koizumi K, Radetzky S, Krohne TU, Poulaki V, Semkova I, Kociok N. Joussen AM, et al. Mol Vis. 2009 Jul 25;15:1418-28. Mol Vis. 2009. PMID: 19641635 Free PMC article.
PURPOSE: The pathophysiology of diabetic retinopathy involves leukocyte adhesion to retinal vasculature, early blood-retinal barrier breakdown, capillary nonperfusion, and endothelial cell death. ...
PURPOSE: The pathophysiology of diabetic retinopathy involves leukocyte adhesion to retinal vasculature, early blood-retinal barrier …
Iris pigment epithelial cells transplanted into the vitreous accumulate at the optic nerve head.
Jordan JF, Semkova I, Kociok N, Welsandt GR, Krieglstein GK, Schraermeyer U. Jordan JF, et al. Graefes Arch Clin Exp Ophthalmol. 2002 May;240(5):403-7. doi: 10.1007/s00417-002-0436-4. Epub 2002 Mar 20. Graefes Arch Clin Exp Ophthalmol. 2002. PMID: 12073064
The injected melanin granules also accumulated at the optic nerve head, indicating that this is most likely a passive process. In sections of the papillary region containing retinal vessels, the IPE cells seemed to have migrated into the superficial tissue of the optic ner …
The injected melanin granules also accumulated at the optic nerve head, indicating that this is most likely a passive process. In sections o …