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2017 2
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2024 1

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Fixed-Dose Subcutaneous C1-Inhibitor Liquid for Prophylactic Treatment of C1-INH-HAE: SAHARA Randomized Study.
Lumry WR, Martinez-Saguer I, Yang WH, Bernstein JA, Jacobs J, Moldovan D, Riedl MA, Johnston DT, Li HH, Tang Y, Schranz J, Lu P, Vardi M, Farkas H; SAHARA study group. Lumry WR, et al. J Allergy Clin Immunol Pract. 2019 May-Jun;7(5):1610-1618.e4. doi: 10.1016/j.jaip.2019.01.021. Epub 2019 Jan 23. J Allergy Clin Immunol Pract. 2019. PMID: 30682573 Free article. Clinical Trial.
In a partial crossover design, 80% of patients were randomized to placebo or pdC1-INH liquid for 14 weeks and crossed over from active to placebo or vice versa for another 14 weeks. The remainder were randomized to pdC1-INH liquid for 28 weeks. ...
In a partial crossover design, 80% of patients were randomized to placebo or pdC1-INH liquid for 14 weeks and crossed over from active to pl …
Emotional Distress Predicts Reduced Type 2 Diabetes Treatment Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Hoogendoorn CJ, Krause-Steinrauf H, Uschner D, Wen H, Presley CA, Legowski EA, Naik AD, Golden SH, Arends VL, Brown-Friday J, Krakoff JA, Suratt CE, Waltje AH, Cherrington AL, Gonzalez JS; GRADE Research Group. Hoogendoorn CJ, et al. Diabetes Care. 2024 Apr 1;47(4):629-637. doi: 10.2337/dc23-1401. Diabetes Care. 2024. PMID: 38227900 Clinical Trial.

Higher depressive symptoms and diabetes distress at one visit predicted lower adherence at the subsequent 6-month visit (P < 0.0001) but not vice versa. Treatment assignment did not moderate relationships. Patient-reported concerns about diabetes medications mediated th

Higher depressive symptoms and diabetes distress at one visit predicted lower adherence at the subsequent 6-month visit (P < 0.0001) but

PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.
Banerji CRS, Panamarova M, Hebaishi H, White RB, Relaix F, Severini S, Zammit PS. Banerji CRS, et al. Nat Commun. 2017 Dec 18;8(1):2152. doi: 10.1038/s41467-017-01200-4. Nat Commun. 2017. PMID: 29255294 Free PMC article.
DUX4 also inhibits PAX7 from activating its transcriptional target genes and vice versa. Furthermore, PAX7 target gene repression can explain oxidative stress sensitivity and epigenetic changes in FSHD. ...
DUX4 also inhibits PAX7 from activating its transcriptional target genes and vice versa. Furthermore, PAX7 target gene repression can …
Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: support to rural India's public education system and impact on numeracy and literacy scores (STRIPES2).
Keddie S, Fazzio I, Shivalli S, Magill N, Elbourne D, Sharma D, Shekhawat SS, Banerji R, Karnati S, Reddy H, Eble A, Boone P, Frost C. Keddie S, et al. Trials. 2023 Jul 22;24(1):469. doi: 10.1186/s13063-023-07453-3. Trials. 2023. PMID: 37481559 Free PMC article. Clinical Trial.
Building on the design of the earlier CHAMPION/STRIPES trial, villages receiving the health intervention are controls for the education intervention and vice versa. The primary outcome is a combined literacy and numeracy score. ...
Building on the design of the earlier CHAMPION/STRIPES trial, villages receiving the health intervention are controls for the education inte …
Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.
Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J, Lumry WR, Farkas H, Katelaris CH, Sussman GL, Jacobs J, Riedl M, Manning ME, Hebert J, Keith PK, Kivity S, Neri S, Levy DS, Baeza ML, Nathan R, Schwartz LB, Caballero T, Yang W, Crisan I, Hernandez MD, Hussain I, Tarzi M, Ritchie B, Králíčková P, Guilarte M, Rehman SM, Banerji A, Gower RG, Bensen-Kennedy D, Edelman J, Feuersenger H, Lawo JP, Machnig T, Pawaskar D, Pragst I, Zuraw BL; COMPACT Investigators. Longhurst H, et al. N Engl J Med. 2017 Mar 23;376(12):1131-1140. doi: 10.1056/NEJMoa1613627. N Engl J Med. 2017. PMID: 28328347 Free article. Clinical Trial.
We randomly assigned the patients to one of four treatment sequences in a crossover design, each involving two 16-week treatment periods: either 40 IU or 60 IU of CSL830 per kilogram of body weight twice weekly followed by placebo, or vice versa. The primary efficacy end p …
We randomly assigned the patients to one of four treatment sequences in a crossover design, each involving two 16-week treatment periods: ei …
Protocol for a cluster randomised trial in Madhya Pradesh, India: community health promotion and medical provision and impact on neonates (CHAMPION2); and support to rural India's public education system and impact on numeracy and literacy scores (STRIPES2).
Agarwal A, Banerji R, Boone P, Elbourne D, Fazzio I, Frost C, Gopal M, Karnati S, Nair R, Reddy H, Reddy P, Sharma D, Shekhawat SS, Shivalli S. Agarwal A, et al. Trials. 2020 Jun 25;21(1):569. doi: 10.1186/s13063-020-04339-6. Trials. 2020. PMID: 32586400 Free PMC article.
Building on the design of the earlier CHAMPION/STRIPES trial, villages receiving the health intervention are controls for the education intervention and vice versa. The clusters are 196 villages in Satna district, Madhya Pradesh, India: each is at least 5 km from a Communi …
Building on the design of the earlier CHAMPION/STRIPES trial, villages receiving the health intervention are controls for the education inte …