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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
2003 1
2004 1
2005 3
2006 4
2007 3
2008 2
2009 2
2010 1
2011 1
2012 2
2013 2
2014 11
2015 7
2016 5
2017 7
2018 13
2019 12
2020 11
2021 15
2022 7
2023 10
2024 4

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119 results

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Page 1
Gut Microbiota and Obesity: A Role for Probiotics.
Abenavoli L, Scarpellini E, Colica C, Boccuto L, Salehi B, Sharifi-Rad J, Aiello V, Romano B, De Lorenzo A, Izzo AA, Capasso R. Abenavoli L, et al. Nutrients. 2019 Nov 7;11(11):2690. doi: 10.3390/nu11112690. Nutrients. 2019. PMID: 31703257 Free PMC article. Review.
The modulation of the bacterial strains in the digestive tract can help to reshape the metabolic profile in the human obese host as suggested by several data from animal and human studies. ...
The modulation of the bacterial strains in the digestive tract can help to reshape the metabolic profile in the human obese host as s …
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition.
Catalogna G, Moraca F, D'Antona L, Dattilo V, Perrotti G, Lupia A, Costa G, Ortuso F, Iuliano R, Trapasso F, Amato R, Alcaro S, Perrotti N. Catalogna G, et al. Eur J Med Chem. 2019 Dec 1;183:111675. doi: 10.1016/j.ejmech.2019.111675. Epub 2019 Sep 5. Eur J Med Chem. 2019. PMID: 31539779 Review.
Resveratrol (trans-3,4',5-trihydroxystilbene) is a polyphenolic natural product with a well-known polypharmacological profile that places it among the multi-target-directed ligands (MTDLs). ...
Resveratrol (trans-3,4',5-trihydroxystilbene) is a polyphenolic natural product with a well-known polypharmacological profile that pl …
TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma.
Scionti F, Juli G, Rocca R, Polerà N, Nadai M, Grillone K, Caracciolo D, Riillo C, Altomare E, Ascrizzi S, Caparello B, Cerra M, Arbitrio M, Richter SN, Artese A, Alcaro S, Tagliaferri P, Tassone P, Di Martino MT. Scionti F, et al. J Exp Clin Cancer Res. 2023 Mar 27;42(1):71. doi: 10.1186/s13046-023-02633-0. J Exp Clin Cancer Res. 2023. PMID: 36967378 Free PMC article.
Gene and protein expressions were detected by RT-qPCR and western blotting, respectively. Microarray analysis was used to analyze the transcriptome profile. The effect of hit 17 on telomeric structure was evaluated by chromatin immunoprecipitation. ...
Gene and protein expressions were detected by RT-qPCR and western blotting, respectively. Microarray analysis was used to analyze the transc …
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile.
Maruca A, Catalano R, Bagetta D, Mesiti F, Ambrosio FA, Romeo I, Moraca F, Rocca R, Ortuso F, Artese A, Costa G, Alcaro S, Lupia A. Maruca A, et al. Eur J Med Chem. 2019 Nov 1;181:111579. doi: 10.1016/j.ejmech.2019.111579. Epub 2019 Jul 31. Eur J Med Chem. 2019. PMID: 31398616 Review.
In this review, the main natural products of the Mediterranean area are discussed, with particular attention on their anti-cancer properties endowed with multi-target profiles....
In this review, the main natural products of the Mediterranean area are discussed, with particular attention on their anti-cancer properties …
Antileishmanial Activity of Amphotericin B-loaded-PLGA Nanoparticles: An Overview.
Palma E, Pasqua A, Gagliardi A, Britti D, Fresta M, Cosco D. Palma E, et al. Materials (Basel). 2018 Jul 9;11(7):1167. doi: 10.3390/ma11071167. Materials (Basel). 2018. PMID: 29987206 Free PMC article. Review.
The modulation of the structural/morphological properties of nanoparticles allows us to influence various technological parameters, such as the loading capacity and/or the release profile of the encapsulated drug(s). Amongst the biocompatible polymers, poly(D,L-lactide) (P …
The modulation of the structural/morphological properties of nanoparticles allows us to influence various technological parameters, such as …
Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy.
Mollace A, Coluccio ML, Donato G, Mollace V, Malara N. Mollace A, et al. Oncotarget. 2021 Jun 22;12(13):1281-1295. doi: 10.18632/oncotarget.27990. eCollection 2021 Jun 22. Oncotarget. 2021. PMID: 34194625 Free PMC article. Review.
The tumour microenvironment is the result of the activity of many types of cells in various metabolic states, whose metabolites are shared between cells. This cellular complexity results in an availability profile of nutrients and reactive metabolites such as advanced glyc …
The tumour microenvironment is the result of the activity of many types of cells in various metabolic states, whose metabolites are shared b …
Pharmacogenomic Profiling of ADME Gene Variants: Current Challenges and Validation Perspectives.
Arbitrio M, Di Martino MT, Scionti F, Barbieri V, Pensabene L, Tagliaferri P. Arbitrio M, et al. High Throughput. 2018 Dec 18;7(4):40. doi: 10.3390/ht7040040. High Throughput. 2018. PMID: 30567415 Free PMC article. Review.
In the past decades, many efforts have been made to individualize medical treatments, taking into account molecular profiles and the individual genetic background. The development of molecularly targeted drugs and immunotherapy have revolutionized medical treatments but th …
In the past decades, many efforts have been made to individualize medical treatments, taking into account molecular profiles and the …
Recent Advances of Taxol-Loaded Biocompatible Nanocarriers Embedded in Natural Polymer-Based Hydrogels.
Voci S, Gagliardi A, Molinaro R, Fresta M, Cosco D. Voci S, et al. Gels. 2021 Mar 24;7(2):33. doi: 10.3390/gels7020033. Gels. 2021. PMID: 33804970 Free PMC article. Review.
The exploitation of natural polymers as potential materials for drug delivery purposes has favored the modulation of the bioavailability and the pharmacokinetic profiles of the drug, and in this regard, several formulations have been developed that allow the controlled rel …
The exploitation of natural polymers as potential materials for drug delivery purposes has favored the modulation of the bioavailability and …
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile.
Alkhatib M, Salpini R, Carioti L, Ambrosio FA, D'Anna S, Duca L, Costa G, Bellocchi MC, Piermatteo L, Artese A, Santoro MM, Alcaro S, Svicher V, Ceccherini-Silberstein F. Alkhatib M, et al. Microbiol Spectr. 2022 Apr 27;10(2):e0273221. doi: 10.1128/spectrum.02732-21. Epub 2022 Mar 30. Microbiol Spectr. 2022. PMID: 35352942 Free PMC article.
Overall, our study will assist with deciphering the Omicron VOC mutational profile and will shed more light on its clinical implications. This is critical considering that Omicron VOC is currently the predominant variant worldwide. ...
Overall, our study will assist with deciphering the Omicron VOC mutational profile and will shed more light on its clinical implicati …
Post-insertion parameters of PEG-derivatives in phosphocholine-liposomes.
Mare R, Paolino D, Celia C, Molinaro R, Fresta M, Cosco D. Mare R, et al. Int J Pharm. 2018 Dec 1;552(1-2):414-421. doi: 10.1016/j.ijpharm.2018.10.028. Epub 2018 Oct 10. Int J Pharm. 2018. PMID: 30316001
The insertion of specific derivatives into pre-formed colloidal systems has been shown to be a useful method for modifying their pharmacokinetic characteristics and biodistribution profiles. In this experimental work the effect of the post-insertion of different PEG-deriva …
The insertion of specific derivatives into pre-formed colloidal systems has been shown to be a useful method for modifying their pharmacokin …
119 results