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Could dexmedetomidine be repurposed as a glymphatic enhancer?
Trends Pharmacol Sci. 2022 Dec;43(12):1030-1040. doi: 10.1016/j.tips.2022.09.007. Epub 2022 Oct 21.
Trends Pharmacol Sci. 2022.
PMID: 36280451
Free article.
Review.
By contrast, sleep deprivation reduces glymphatic clearance and leads to intracerebral accumulation of metabolic waste, suggesting an underlying mechanism linking sleep disturbances with neurodegenerative diseases. ...As recently developed dexmedetomidine formulations enab …
By contrast, sleep deprivation reduces glymphatic clearance and leads to intracerebral accumulation of metabolic waste, suggesting an …
A fugacity model assessment of ibuprofen, diclofenac, carbamazepine, and their transformation product concentrations in an aquatic environment.
Nurmi TMA, Kiljunen TK, Knuutinen JS.
Nurmi TMA, et al.
Environ Sci Pollut Res Int. 2019 Jan;26(1):328-341. doi: 10.1007/s11356-018-3485-x. Epub 2018 Nov 5.
Environ Sci Pollut Res Int. 2019.
PMID: 30397752
Free PMC article.
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Quantifying the total environmental impacts of an industrial symbiosis - a comparison of process-, hybrid and input-output life cycle assessment.
Mattila TJ, Pakarinen S, Sokka L.
Mattila TJ, et al.
Environ Sci Technol. 2010 Jun 1;44(11):4309-14. doi: 10.1021/es902673m.
Environ Sci Technol. 2010.
PMID: 20408541
Local co-operation in industrial symbioses can reduce raw material use and waste disposal, but material and energy flows extending outside symbiosis boundaries can cause considerable environmental impacts. ...
Local co-operation in industrial symbioses can reduce raw material use and waste disposal, but material and energy flows extending ou …
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