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Year Number of Results
1972 1
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2000 1
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2009 2
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33 results

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Page 1
GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Tsukui D, Kimura Y, Kono H. Tsukui D, et al. iScience. 2023 Jul 11;26(8):107293. doi: 10.1016/j.isci.2023.107293. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520709 Free PMC article.
CD11c expression decreased on Syk-knockout monocytes and macrophages; it was upregulated by forkhead box protein O1 (FOXO1) after stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF), and c-Jun amino-terminal kinase (JNK) mediated SYK signaling to FOX …
CD11c expression decreased on Syk-knockout monocytes and macrophages; it was upregulated by forkhead box protein O1 (FOXO1) after stimulatio …
mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression.
Harachi M, Masui K, Okamura Y, Tsukui R, Mischel PS, Shibata N. Harachi M, et al. Int J Mol Sci. 2018 Oct 21;19(10):3267. doi: 10.3390/ijms19103267. Int J Mol Sci. 2018. PMID: 30347859 Free PMC article. Review.
In this article, we depict the recent findings on the role of mTOR complexes in cancer as a master regulator of cancer metabolism and a potential sensor of nutrients, especially focusing on glucose and amino acid sensing in cancer. Novel and detailed molecular mechanisms t …
In this article, we depict the recent findings on the role of mTOR complexes in cancer as a master regulator of cancer metabolism and a pote …
The ion balance of Shotokuseki extract promotes filaggrin fragmentation and increases amino acid production and pyrrolidone carboxylic acid content in three-dimensional cultured human epidermis.
Tsukui K, Kakiuchi T, Suzuki M, Sakurai H, Tokudome Y. Tsukui K, et al. Nat Prod Bioprospect. 2022 Oct 17;12(1):37. doi: 10.1007/s13659-022-00353-0. Nat Prod Bioprospect. 2022. PMID: 36245006 Free PMC article.
The purpose of this study was to determine the penetration of ions in Shotokuseki extract (SE) into the three-dimensional cultured epidermis and the effect of NMF on the biosynthesis of amino acids and pyrrolidone carboxylic acid formation. Various ions, amino acids …
The purpose of this study was to determine the penetration of ions in Shotokuseki extract (SE) into the three-dimensional cultured epidermis …
Bacterial degradation of microcystins and nodularin.
Imanishi S, Kato H, Mizuno M, Tsuji K, Harada K. Imanishi S, et al. Chem Res Toxicol. 2005 Mar;18(3):591-8. doi: 10.1021/tx049677g. Chem Res Toxicol. 2005. PMID: 15777098
They are, respectively, cyclic heptapeptides and cyclic pentapeptides containing a characteristic beta-amino acid residue, (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4(E ),6(E)-dienoic acid (Adda). Strain B-9 isolated from Lake Tsukui, Japa …
They are, respectively, cyclic heptapeptides and cyclic pentapeptides containing a characteristic beta-amino acid residue, (2S,3S,8S, …
Minimum amino acid residues of an alpha-helical peptide leading to lipid nanodisc formation.
Imura T, Tsukui Y, Sakai K, Sakai H, Taira T, Kitamoto D. Imura T, et al. J Oleo Sci. 2014;63(11):1203-8. doi: 10.5650/jos.ess14172. Epub 2014 Oct 21. J Oleo Sci. 2014. PMID: 25341499 Free article.
Nanodiscs are a relatively new class of nanoparticles composed of amphiphilic alpha-helical scaffold peptides and a phospholipid bilayer, and find potential applications in various fields. In order to identify the minimum number of amino acid residues of an amphiphilic alp …
Nanodiscs are a relatively new class of nanoparticles composed of amphiphilic alpha-helical scaffold peptides and a phospholipid bilayer, an …
Identification of two novel deletion mutations in glucose-6-phosphate dehydrogenase gene causing hemolytic anemia.
Hirono A, Fujii H, Miwa S. Hirono A, et al. Blood. 1995 Feb 15;85(4):1118-21. Blood. 1995. PMID: 7849299 Free article.
Case no. 1 had a 3-nucleotide deletion in exon 6 predicting a deletion of a serine at amino acid 188 or 189, which caused a class 1 variant G6PD Tsukui. Case no. 2 had a 3-nucleotide deletion in exon 5 predicting a deletion of a lysine at residue 95, which caused a …
Case no. 1 had a 3-nucleotide deletion in exon 6 predicting a deletion of a serine at amino acid 188 or 189, which caused a class 1 v …
L-amino acid oxidase activity of an antineoplastic factor of a marine mollusk and its relationship to cytotoxicity.
Iijima R, Kisugi J, Yamazaki M. Iijima R, et al. Dev Comp Immunol. 2003 Jun-Jul;27(6-7):505-12. doi: 10.1016/s0145-305x(02)00140-4. Dev Comp Immunol. 2003. PMID: 12697307
Dolabellanin A (DAA), an antineoplastic protein of an ocean mollusk, was shown to have L-amino acid oxidase (LAAO, EC 1.4.3.2) activity. With the addition of DAA, a cytotoxic concentration of hydrogen peroxide was detected in the culture medium of EL-4 murine lymphoma cell …
Dolabellanin A (DAA), an antineoplastic protein of an ocean mollusk, was shown to have L-amino acid oxidase (LAAO, EC 1.4.3.2) activi …
Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking.
Zhang Z, Bai M, Barbosa GO, Chen A, Wei Y, Luo S, Wang X, Wang B, Tsukui T, Li H, Sheppard D, Kornberg TB, Ma DK. Zhang Z, et al. Sci Adv. 2020 Feb 12;6(7):eaay7667. doi: 10.1126/sciadv.aay7667. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32095531 Free PMC article.
From an RNA interference screen, we identified an uncharacterized Caenorhabditis elegans gene tmem-131, deficiency of which impairs collagen production and activates ER stress response. We find that amino termini of human TMEM131 contain bacterial PapD chaperone-like domai …
From an RNA interference screen, we identified an uncharacterized Caenorhabditis elegans gene tmem-131, deficiency of which impairs collagen …
Tbx genes and limb identity in chick embryo development.
Isaac A, Rodriguez-Esteban C, Ryan A, Altabef M, Tsukui T, Patel K, Tickle C, Izpisúa-Belmonte JC. Isaac A, et al. Development. 1998 May;125(10):1867-75. doi: 10.1242/dev.125.10.1867. Development. 1998. PMID: 9550719
33 results