A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies.
Costigan D, Fenn J, Yen S, Ilott N, Bullers S, Hale J, Greenhalf W, Conibear E, Koycheva A, Madon K, Jahan I, Huang M, Badhan A, Parker E, Rosadas C, Jones K, McClure M, Tedder R, Taylor G, Baillie KJ, Semple MG, Openshaw PJM, Pearson C, Johnson J; INSTINCT Study Group; ISARIC4C investigators; Lalvani A, Thornton EE.
Costigan D, et al.
Mucosal Immunol. 2024 Feb;17(1):111-123. doi: 10.1016/j.mucimm.2023.11.005. Epub 2023 Nov 22.
Mucosal Immunol. 2024.
PMID: 37995912
Free PMC article.
The relationship between gastrointestinal tract infection, the host immune response, and the clinical outcome of disease is not well understood in COVID-19. ...Combining two prospective cohort studies, International Severe Acute Respiratory and emerging Infections Consorti …
The relationship between gastrointestinal tract infection, the host immune response, and the clinical outcome of disease is not well …