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Year Number of Results
1984 1
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1996 3
1997 1
1998 1
1999 1
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2004 2
2007 1
2008 1
2010 2
2011 1
2012 1
2013 1
2014 2
2016 1
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2019 3
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2022 1
2024 0

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30 results

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The receptor for advanced glycation end-products (RAGE) is an important pattern recognition receptor (PRR) for inflammaging.
Teissier T, Boulanger É. Teissier T, et al. Biogerontology. 2019 Jun;20(3):279-301. doi: 10.1007/s10522-019-09808-3. Epub 2019 Apr 9. Biogerontology. 2019. PMID: 30968282 Review.
We suggest here that, through its interconnection with immunity, senescence, mitochondrial dysfunction and inflammasome activation, RAGE is a key contributor to inflammaging and that the pro-longevity effects seen upon blocking RAGE, or upon its deletion, are thus the resu …
We suggest here that, through its interconnection with immunity, senescence, mitochondrial dysfunction and inflammasome activation, RAGE is …
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.
Benslimane Y, Sánchez-Osuna M, Coulombe-Huntington J, Bertomeu T, Henry D, Huard C, Bonneil É, Thibault P, Tyers M, Harrington L. Benslimane Y, et al. Aging Cell. 2021 Apr;20(4):e13331. doi: 10.1111/acel.13331. Epub 2021 Mar 4. Aging Cell. 2021. PMID: 33660365 Free PMC article.
Telomere erosion in cells with insufficient levels of the telomerase reverse transcriptase (TERT), contributes to age-associated tissue dysfunction and senescence, and p53 plays a crucial role in this response. We undertook a genome-wide CRISPR screen to identify gene d …
Telomere erosion in cells with insufficient levels of the telomerase reverse transcriptase (TERT), contributes to age-associated tissue dysf …
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex.
Rizzolo K, Yu AYH, Ologbenla A, Kim SR, Zhu H, Ishimori K, Thibault G, Leung E, Zhang YW, Teng M, Haniszewski M, Miah N, Phanse S, Minic Z, Lee S, Caballero JD, Babu M, Tsai FTF, Saio T, Houry WA. Rizzolo K, et al. Nat Commun. 2021 Jan 12;12(1):281. doi: 10.1038/s41467-020-20553-x. Nat Commun. 2021. PMID: 33436616 Free PMC article.
Bioinformatic analyses demonstrate conservation of the close proximity of tig, the gene coding for TF, and genes coding for ClpXP, suggesting a functional interaction. ...
Bioinformatic analyses demonstrate conservation of the close proximity of tig, the gene coding for TF, and genes coding for ClpXP, su …
Differential Modulation of Quorum Sensing Signaling through QslA in Pseudomonas aeruginosa Strains PAO1 and PA14.
Sana TG, Lomas R, Gimenez MR, Laubier A, Soscia C, Chauvet C, Conesa A, Voulhoux R, Ize B, Bleves S. Sana TG, et al. J Bacteriol. 2019 Oct 4;201(21):e00362-19. doi: 10.1128/JB.00362-19. Print 2019 Nov 1. J Bacteriol. 2019. PMID: 31405911 Free PMC article.
After confirming that QslA protein was highly produced in PAO1 but not in the PA14 strain, we obtained evidence showing that a PAO1 deletion strain of qslA has faster QS gene expression kinetics than PA14. Moreover, known virulence factors activated by QS, such as ( …
After confirming that QslA protein was highly produced in PAO1 but not in the PA14 strain, we obtained evidence showing that a PAO1 delet …
SARS-CoV-2 genome quantification in wastewaters at regional and city scale allows precise monitoring of the whole outbreaks dynamics and variants spreading in the population.
Wurtzer S, Waldman P, Levert M, Cluzel N, Almayrac JL, Charpentier C, Masnada S, Gillon-Ritz M, Mouchel JM, Maday Y, Boni M; OBEPINE Consortium; AP-HP Virologist Group; Marechal V, Moulin L. Wurtzer S, et al. Sci Total Environ. 2022 Mar 1;810:152213. doi: 10.1016/j.scitotenv.2021.152213. Epub 2021 Dec 9. Sci Total Environ. 2022. PMID: 34896511 Free PMC article.
Moreover, variants of concern (VOC) emerged due to the selection pressure. We developed a specific RT-qPCR method targeting the deletion H69-V70 in the spike protein, using this deletion as a proxy of the B.1.1.7 presence in the wastewater. ...
Moreover, variants of concern (VOC) emerged due to the selection pressure. We developed a specific RT-qPCR method targeting the deletion …
Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling.
Li H, Li J, Han R, Deng X, Shi J, Huang H, Hamad N, McCaughley A, Liu J, Wang C, Chen K, Wei D, Qiang J, Thatcher S, Wu Y, Liu C, Thibault O, Wei X, Chen S, Qian H, Zhou BP, Xu P, Yang XH. Li H, et al. Neoplasia. 2019 Dec;21(12):1151-1163. doi: 10.1016/j.neo.2019.08.005. Epub 2019 Nov 26. Neoplasia. 2019. PMID: 31783316 Free PMC article.
The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.
Thibault G, Ismail N, Ng DT. Thibault G, et al. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20597-602. doi: 10.1073/pnas.1117184109. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143797 Free PMC article.
One of the best-characterized pathways, the unfolded protein response (UPR), is responsible for maintaining endoplasmic reticulum (ER) homeostasis. The highly conserved Ire1 branch regulates hundreds of gene targets by activating a UPR-specific transcription factor. To und …
One of the best-characterized pathways, the unfolded protein response (UPR), is responsible for maintaining endoplasmic reticulum (ER) homeo …
30 results