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Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial.
El-Heis S, D'Angelo S, Curtis EM, Healy E, Moon RJ, Crozier SR, Inskip H, Cooper C, Harvey NC, Godfrey KM; MAVIDOS Trial Group. El-Heis S, et al. Br J Dermatol. 2022 Nov;187(5):659-666. doi: 10.1111/bjd.21721. Epub 2022 Aug 3. Br J Dermatol. 2022. PMID: 35763390 Free PMC article. Clinical Trial.
METHODS: Within the UK Maternal Vitamin D Osteoporosis Study (MAVIDOS) double-blind, randomized placebo-controlled trial, we examined the relationship of maternal vitamin D supplementation during pregnancy with offspring atopic eczema at ages 12, 24 and 48 months. I …
METHODS: Within the UK Maternal Vitamin D Osteoporosis Study (MAVIDOS) double-blind, randomized placebo-controlled trial, we e …
Analysis of the MAVIDOS trial - Author's reply.
Harvey NC, Moon RJ, Inskip HM, Godfrey KM, Cooper C; MAVIDOS Trial Group. Harvey NC, et al. Lancet Diabetes Endocrinol. 2017 May;5(5):328-329. doi: 10.1016/S2213-8587(17)30113-4. Lancet Diabetes Endocrinol. 2017. PMID: 28434488 Free PMC article. No abstract available.
MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. The MAVIDOS Study Group.
Harvey NC, Javaid K, Bishop N, Kennedy S, Papageorghiou AT, Fraser R, Gandhi SV, Schoenmakers I, Prentice A, Cooper C. Harvey NC, et al. Trials. 2012 Feb 7;13:13. doi: 10.1186/1745-6215-13-13. Trials. 2012. PMID: 22314083 Free PMC article. Clinical Trial.
MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR. ...METHODS/DESIGN: Women have their vitamin D status assessed after ultrasound scanning in the t
MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis
Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial.
Curtis EM, Krstic N, Cook E, D'Angelo S, Crozier SR, Moon RJ, Murray R, Garratt E, Costello P, Cleal J, Ashley B, Bishop NJ, Kennedy S, Papageorghiou AT, Schoenmakers I, Fraser R, Gandhi SV, Prentice A, Javaid MK, Inskip HM, Godfrey KM, Bell CG, Lillycrop KA, Cooper C, Harvey NC; MAVIDOS Trial Group. Curtis EM, et al. J Bone Miner Res. 2019 Feb;34(2):231-240. doi: 10.1002/jbmr.3603. Epub 2019 Jan 18. J Bone Miner Res. 2019. PMID: 30321476 Free PMC article. Clinical Trial.
We have previously demonstrated inverse associations between maternal 25(OH)-vitamin D status and perinatal DNA methylation at the retinoid-X-receptor-alpha (RXRA) locus and between RXRA methylation and offspring bone mass. In this study, we used an existing randomized trial
We have previously demonstrated inverse associations between maternal 25(OH)-vitamin D status and perinatal DNA methylation at the retinoid- …
Pregnancy Vitamin D Supplementation and Childhood Bone Mass at Age 4 Years: Findings From the Maternal Vitamin D Osteoporosis Study (MAVIDOS) Randomized Controlled Trial.
Curtis EM, Moon RJ, D'Angelo S, Crozier SR, Bishop NJ, Gopal-Kothandapani JS, Kennedy SH, Papageorghiou AT, Fraser R, Gandhi SV, Schoenmakers I, Prentice A, Inskip HM, Godfrey KM, Javaid MK, Eastell R, Cooper C, Harvey NC; MAVIDOS Trial Group. Curtis EM, et al. JBMR Plus. 2022 Jun 11;6(7):e10651. doi: 10.1002/jbm4.10651. eCollection 2022 Jul. JBMR Plus. 2022. PMID: 35866154 Free PMC article.
In the Maternal Vitamin D Osteoporosis Study (MAVIDOS) randomized trial, vitamin D supplementation in pregnancy did not lead to greater neonatal bone mass across the trial as a whole, but, in a prespecified secondary analysis by season of birth, led to greate …
In the Maternal Vitamin D Osteoporosis Study (MAVIDOS) randomized trial, vitamin D supplementation in pregnancy did not lead t …
Bone turnover in pregnancy, measured by urinary CTX, is influenced by vitamin D supplementation and is associated with maternal bone health: findings from the Maternal Vitamin D Osteoporosis Study (MAVIDOS) trial.
Curtis EM, Parsons C, Maslin K, D'Angelo S, Moon RJ, Crozier SR, Gossiel F, Bishop NJ, Kennedy SH, Papageorghiou AT, Fraser R, Gandhi SV, Prentice A, Inskip HM, Godfrey KM, Schoenmakers I, Javaid MK, Eastell R, Cooper C, Harvey NC; MAVIDOS Trial Group. Curtis EM, et al. Am J Clin Nutr. 2021 Nov 8;114(5):1600-1611. doi: 10.1093/ajcn/nqab264. Am J Clin Nutr. 2021. PMID: 34297067 Free PMC article. Clinical Trial.
OBJECTIVES: We investigated changes across pregnancy in a marker of maternal bone resorption, urinary C-terminal telopeptide of type I collagen (CTX), the influence of gestational vitamin D supplementation, and associations between CTX and maternal postnatal bone indices. METHODS …
OBJECTIVES: We investigated changes across pregnancy in a marker of maternal bone resorption, urinary C-terminal telopeptide of type I colla …
The relationship between maternal self-efficacy, compliance and outcome in a trial of vitamin D supplementation in pregnancy.
Barker M, D'Angelo S, Ntani G, Lawrence W, Baird J, Jarman M, Vogel C, Inskip H, Cooper C, Harvey NC; MAVIDOS Study Group. Barker M, et al. Osteoporos Int. 2017 Jan;28(1):77-84. doi: 10.1007/s00198-016-3721-5. Epub 2016 Aug 22. Osteoporos Int. 2017. PMID: 27549309 Free PMC article. Clinical Trial.
INTRODUCTION: The relationship between self-efficacy (the belief that one can carry out a behaviour), compliance with study protocol and outcome was explored within a randomised, double-blind, placebo-controlled trial of vitamin D supplementation in pregnancy. METHODS: In …
INTRODUCTION: The relationship between self-efficacy (the belief that one can carry out a behaviour), compliance with study protocol and out …
Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial.
Cooper C, Harvey NC, Bishop NJ, Kennedy S, Papageorghiou AT, Schoenmakers I, Fraser R, Gandhi SV, Carr A, D'Angelo S, Crozier SR, Moon RJ, Arden NK, Dennison EM, Godfrey KM, Inskip HM, Prentice A, Mughal MZ, Eastell R, Reid DM, Javaid MK; MAVIDOS Study Group. Cooper C, et al. Lancet Diabetes Endocrinol. 2016 May;4(5):393-402. doi: 10.1016/S2213-8587(16)00044-9. Epub 2016 Mar 2. Lancet Diabetes Endocrinol. 2016. PMID: 26944421 Free PMC article. Clinical Trial.
METHODS: The Maternal Vitamin D Osteoporosis Study (MAVIDOS) was a multicentre, double-blind, randomised, placebo-controlled trial that recruited pregnant women from three study sites in the UK (Southampton, Oxford, and Sheffield). ...We noted no significant differe …
METHODS: The Maternal Vitamin D Osteoporosis Study (MAVIDOS) was a multicentre, double-blind, randomised, placebo-controlled trial
Maternal pregnancy vitamin D supplementation increases offspring bone formation in response to mechanical loading: Findings from a MAVIDOS Trial sub-study.
Gopal-Kothandapani JS, Rigby AS, Harrison R, Eastell R, Moon RJ, Curtis EM, Cooper C, Harvey NC, Bishop N. Gopal-Kothandapani JS, et al. J Musculoskelet Neuronal Interact. 2020 Mar 3;20(1):4-11. J Musculoskelet Neuronal Interact. 2020. PMID: 32131365 Free PMC article. Clinical Trial.
The Maternal Vitamin D Osteoporosis (MAVIDOS) trial reported higher total body bone mineral content in winter-born infants of mothers receiving vitamin D supplementation [1000 IU/day cholecalciferol] compared with placebo from 14 weeks gestation until delivery. This …
The Maternal Vitamin D Osteoporosis (MAVIDOS) trial reported higher total body bone mineral content in winter-born infants of …
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