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Implication of SUMO E3 ligases in nucleotide excision repair.
Tsuge M, Kaneoka H, Masuda Y, Ito H, Miyake K, Iijima S. Tsuge M, et al. Cytotechnology. 2015 Aug;67(4):681-7. doi: 10.1007/s10616-014-9762-8. Epub 2014 Jul 10. Cytotechnology. 2015. PMID: 25008297 Free PMC article.
However, how SUMOylation modulates NER has not yet been elucidated. In the present study, we performed RNAi knockdown of SUMO E3 ligases and found that, in addition to PIASy, the polycomb protein Pc2 affected the repair of cyclobutane pyrimidine dimers. PIAS1 affected both …
However, how SUMOylation modulates NER has not yet been elucidated. In the present study, we performed RNAi knockdown of SUMO E3 liga …
SUMOylation of damaged DNA-binding protein DDB2.
Tsuge M, Masuda Y, Kaneoka H, Kidani S, Miyake K, Iijima S. Tsuge M, et al. Biochem Biophys Res Commun. 2013 Aug 16;438(1):26-31. doi: 10.1016/j.bbrc.2013.07.013. Epub 2013 Jul 13. Biochem Biophys Res Commun. 2013. PMID: 23860269
Here, we demonstrated that DDB2 was SUMOylated in a UV-dependent manner, and its major SUMO E3 ligase was PIASy as determined by RNA interference-mediated knockdown. ...
Here, we demonstrated that DDB2 was SUMOylated in a UV-dependent manner, and its major SUMO E3 ligase was PIASy as determined by RNA …
Moloney murine leukemia virus integrase and reverse transcriptase interact with PML proteins.
Okino Y, Inayoshi Y, Kojima Y, Kidani S, Kaneoka H, Honkawa A, Higuchi H, Nishijima K, Miyake K, Iijima S. Okino Y, et al. J Biochem. 2012 Aug;152(2):161-9. doi: 10.1093/jb/mvs063. Epub 2012 Jun 7. J Biochem. 2012. PMID: 22685230
In infected cells, interaction between the integrase and PML was also observed. Transient expression of PIASy and SUMO proteins facilitated SUMOylation of the integrase but had no apparent effects on the interaction with PML. ...
In infected cells, interaction between the integrase and PML was also observed. Transient expression of PIASy and SUMO proteins facil …
Sumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiation.
Sato Y, Miyake K, Kaneoka H, Iijima S. Sato Y, et al. J Biol Chem. 2006 Aug 4;281(31):21629-21639. doi: 10.1074/jbc.M600852200. Epub 2006 May 30. J Biol Chem. 2006. PMID: 16735515 Free article.
The sumoylation of CCAAT/enhancer-binding proteins (C/EBPs) by small ubiquitin-related modifier-1 (SUMO-1) has been reported recently. In this study, we investigated the functional role of the sumoylation of C/EBPalpha in the differentiation of hepatocytes. ...These findin …
The sumoylation of CCAAT/enhancer-binding proteins (C/EBPs) by small ubiquitin-related modifier-1 (SUMO-1) has been reported recently …