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Klotho: An Elephant in Aging Research.
Cheikhi A, Barchowsky A, Sahu A, Shinde SN, Pius A, Clemens ZJ, Li H, Kennedy CA, Hoeck JD, Franti M, Ambrosio F. Cheikhi A, et al. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):1031-1042. doi: 10.1093/gerona/glz061. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30843026 Free PMC article. Review.
This single protein was and is remarkable in that its absence in mice conferred an accelerated aging, or progeroid, phenotype with a dramatically shortened life span. On the other hand, genetic overexpression extended both health span and life span by an impr …
This single protein was and is remarkable in that its absence in mice conferred an accelerated aging, or progeroid, phenotype with a dramati …
Radical Chemistry and Cytotoxicity of Bioreductive 3-Substituted Quinoxaline Di-N-Oxides.
Anderson RF, Yadav P, Shinde SS, Hong CR, Pullen SM, Reynisson J, Wilson WR, Hay MP. Anderson RF, et al. Chem Res Toxicol. 2016 Aug 15;29(8):1310-24. doi: 10.1021/acs.chemrestox.6b00133. Epub 2016 Jul 29. Chem Res Toxicol. 2016. PMID: 27380897
A series of water-soluble 3-trifluoromethyl (4-10), 3-phenyl (11-19), and 3-methyl (20-21) substituted QDO compounds were designed to span a range of electron affinities consistent with bioreduction. ...
A series of water-soluble 3-trifluoromethyl (4-10), 3-phenyl (11-19), and 3-methyl (20-21) substituted QDO compounds were designed to spa …
Cotranslational folding inhibits translocation from within the ribosome-Sec61 translocon complex.
Conti BJ, Elferich J, Yang Z, Shinde U, Skach WR. Conti BJ, et al. Nat Struct Mol Biol. 2014 Mar;21(3):228-35. doi: 10.1038/nsmb.2779. Epub 2014 Feb 23. Nat Struct Mol Biol. 2014. PMID: 24561504 Free PMC article.
These studies identify an enclosed compartment within the assembled RTC that allows a short span of nascent chain to reversibly abort translocation in a substrate-specific manner....
These studies identify an enclosed compartment within the assembled RTC that allows a short span of nascent chain to reversibly abort …
Serratiopeptidase Niosomal Gel with Potential in Topical Delivery.
Shinde UA, Kanojiya SS. Shinde UA, et al. J Pharm (Cairo). 2014;2014:382959. doi: 10.1155/2014/382959. Epub 2014 Mar 20. J Pharm (Cairo). 2014. PMID: 26556195 Free PMC article.
The entrapment efficiency was found to be influenced by the molar ratio of Span 40 : cholesterol and concentration of SRP in noisome. The developed niosomes were characterized for morphology, particle size, and in vitro release. ...Ex vivo permeation and in vivo anti-infla …
The entrapment efficiency was found to be influenced by the molar ratio of Span 40 : cholesterol and concentration of SRP in noisome. …
Successive explosions in Mumbai the economic center of India.
Krishnamurthy R, Daundkar BB, Malve MK. Krishnamurthy R, et al. J Clin Forensic Med. 2006 Aug-Nov;13(6-8):311-5. doi: 10.1016/j.jcfm.2006.06.020. J Clin Forensic Med. 2006. PMID: 17055401
Mumbai the economic center of India was attacked by a series of bomb blasts at twelve different places within a span of an hour on 12th March 1993. The main explosive used was RDX [Krishnamurthy R, Malve MK, Shinde BM. ...
Mumbai the economic center of India was attacked by a series of bomb blasts at twelve different places within a span of an hour on 12 …
Effect of sodium triphosphate and sodium hexametaphosphate on properties of buffalo milk protein concentrate 60 (BMPC60) powder.
Shinde AP, Meena GS, Handge JU. Shinde AP, et al. J Food Sci Technol. 2021 May;58(5):1996-2006. doi: 10.1007/s13197-020-04712-y. Epub 2020 Aug 17. J Food Sci Technol. 2021. PMID: 33897036 Free PMC article.
Addition of STP-SHMP mixture in 2.53 UFR noticeably improved the solubility, flowability, water binding, oil binding, foaming capacity, foam and thermal stability and, viscosity of treated MPC60 powder over control powder. The DeBroukere (D(43)) mean, d(50), specific surface area …
Addition of STP-SHMP mixture in 2.53 UFR noticeably improved the solubility, flowability, water binding, oil binding, foaming capacity, foam …
Reactor design and integration with product detection to accelerate screening of electrocatalysts for carbon dioxide reduction.
Jones RJR, Wang Y, Lai Y, Shinde A, Gregoire JM. Jones RJR, et al. Rev Sci Instrum. 2018 Dec;89(12):124102. doi: 10.1063/1.5049704. Rev Sci Instrum. 2018. PMID: 30599585
Performing accelerated screening to enable exploration of a broad span of catalyst materials poses additional challenges due to the long time scales associated with accumulation of reaction products and the detection of the reaction products with traditional separation-bas …
Performing accelerated screening to enable exploration of a broad span of catalyst materials poses additional challenges due to the l …
Self-assembled single-crystal ferromagnetic iron nanowires formed by decomposition.
Mohaddes-Ardabili L, Zheng H, Ogale SB, Hannoyer B, Tian W, Wang J, Lofland SE, Shinde SR, Zhao T, Jia Y, Salamanca-Riba L, Schlom DG, Wuttig M, Ramesh R. Mohaddes-Ardabili L, et al. Nat Mater. 2004 Aug;3(8):533-8. doi: 10.1038/nmat1162. Epub 2004 Jul 25. Nat Mater. 2004. PMID: 15273743
This leads to the spontaneous formation of an array of single-crystalline alpha-Fe nanowires embedded in LaSrFeO(4) matrix, which grow perpendicular to the substrate and span the entire film thickness. The diameter and spacing of the nanowires are controlled directly by de …
This leads to the spontaneous formation of an array of single-crystalline alpha-Fe nanowires embedded in LaSrFeO(4) matrix, which grow perpe …