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Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression.
Sci Rep. 2019 Feb 5;9(1):1405. doi: 10.1038/s41598-018-38345-1.
Sci Rep. 2019.
PMID: 30723259
Free PMC article.
Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non-Small Cell Lung Cancer Cells.
Sohoni S, Ghosh P, Wang T, Kalainayakan SP, Vidal C, Dey S, Konduri PC, Zhang L.
Sohoni S, et al.
Cancer Res. 2019 May 15;79(10):2511-2525. doi: 10.1158/0008-5472.CAN-18-2156. Epub 2019 Mar 22.
Cancer Res. 2019.
PMID: 30902795
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