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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 2
1975 2
1976 1
1977 1
1979 1
1981 1
1983 3
1984 2
1985 2
1986 6
1987 3
1988 3
1989 5
1990 2
1991 15
1992 8
1993 5
1994 14
1995 11
1996 18
1997 14
1998 18
1999 30
2000 15
2001 15
2002 20
2003 14
2004 19
2005 16
2006 28
2007 15
2008 23
2009 32
2010 27
2011 35
2012 36
2013 34
2014 43
2015 41
2016 43
2017 36
2018 38
2019 28
2020 28
2021 43
2022 24
2023 27
2024 11

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793 results

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Page 1
CD8+ lymphocytes do not impact SIV reservoir establishment under ART.
Statzu M, Jin W, Fray EJ, Wong AKH, Kumar MR, Ferrer E, Docken SS, Pinkevych M, McBrien JB, Fennessey CM, Keele BF, Liang S, Harper JL, Mutascio S, Franchitti L, Wang H, Cicetti D, Bosinger SE, Carnathan DG, Vanderford TH, Margolis DM, Garcia-Martinez JV, Chahroudi A, Paiardini M, Siliciano J, Davenport MP, Kulpa DA, Siliciano RS, Silvestri G. Statzu M, et al. Nat Microbiol. 2023 Feb;8(2):299-308. doi: 10.1038/s41564-022-01311-9. Epub 2023 Jan 23. Nat Microbiol. 2023. PMID: 36690860 Free PMC article.
Here we examined the effect of CD8(+) T cells on formation of the latent reservoir in simian immunodeficiency virus (SIV)-infected macaques by performing experimental CD8(+) depletion either before infection or before early (that is, day 14 post-infection) ART initiation. …
Here we examined the effect of CD8(+) T cells on formation of the latent reservoir in simian immunodeficiency virus (SIV)-infected ma …
Combination recombinant simian or chimpanzee adenoviral vectors for vaccine development.
Cheng C, Wang L, Ko SY, Kong WP, Schmidt SD, Gall JGD, Colloca S, Seder RA, Mascola JR, Nabel GJ. Cheng C, et al. Vaccine. 2015 Dec 16;33(51):7344-7351. doi: 10.1016/j.vaccine.2015.10.023. Epub 2015 Oct 26. Vaccine. 2015. PMID: 26514419 Free PMC article.
In this study, we investigated the potential of low seroprevalence non-human primate rAd vectors to stimulate cellular and humoral responses using HIV/SIV Env glycoprotein (gp) as the representative antigen. Mice were immunized with novel simian or chimpanzee rAd (rSAV or …
In this study, we investigated the potential of low seroprevalence non-human primate rAd vectors to stimulate cellular and humoral responses …
Simian immunodeficiency virus-infected rhesus macaques with AIDS co-develop cardiovascular pathology and encephalitis.
White KS, Walker JA, Wang J, Autissier P, Miller AD, Abuelezan NN, Burrack R, Li Q, Kim WK, Williams KC. White KS, et al. Front Immunol. 2023 Oct 27;14:1240946. doi: 10.3389/fimmu.2023.1240946. eCollection 2023. Front Immunol. 2023. PMID: 37965349 Free PMC article.
We sought to investigate if cardiac pathology (inflammation, fibrosis, cardiomyocyte damage) and CNS pathology (encephalitis) develop together during simian immunodeficiency virus (SIV) infection and if their co-development is linked with monocyte/macrophage activation. .. …
We sought to investigate if cardiac pathology (inflammation, fibrosis, cardiomyocyte damage) and CNS pathology (encephalitis) develop togeth …
Simian homologues of Epstein-Barr virus.
Wang F, Rivailler P, Rao P, Cho Y. Wang F, et al. Philos Trans R Soc Lond B Biol Sci. 2001 Apr 29;356(1408):489-97. doi: 10.1098/rstb.2000.0776. Philos Trans R Soc Lond B Biol Sci. 2001. PMID: 11313007 Free PMC article. Review.
However, the New World LCV genome has significant and interesting differences from EBV and other Old World LCVs despite similar biological properties. Thus, the simian homologues of EBV can provide an important animal model for studying LCV pathogenesis, and the similariti …
However, the New World LCV genome has significant and interesting differences from EBV and other Old World LCVs despite similar biological p …
Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies.
Hora B, Li H, Shen X, Martin M, Chen Y, Berry M, Evangelous T, Macintyre AN, Arus-Altuz A, Wang S, Singh A, Zhao C, De Naeyer N, DeMarco T, Kuykendall C, Gurley T, Saunders KO, Denny T, Moody MA, Misamore J, Lewis MG, Wiehe K, Cain DW, Montefiori DC, Shaw GM, Williams WB. Hora B, et al. Cell Rep. 2023 Mar 28;42(3):112255. doi: 10.1016/j.celrep.2023.112255. Epub 2023 Mar 14. Cell Rep. 2023. PMID: 36924501 Free PMC article.
Here, we describe a neonatal model for heterologous HIV-1 nAb induction in pathogenic simian-HIV (SHIV)-infected rhesus macaques (RMs). Viral envelope (env) evolution showed mutations at multiple sites, including nAb epitopes. ...
Here, we describe a neonatal model for heterologous HIV-1 nAb induction in pathogenic simian-HIV (SHIV)-infected rhesus macaques (RMs …
Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.
Vidal SJ, Bekerman E, Hansen D, Lu B, Wang K, Mwangi J, Rowe W, Campigotto F, Zheng J, Kato D, Chandrashekar A, Barrett J, Patel S, Wan H, Anioke T, Mercado NB, Nkolola JP, Ferguson MJ, Rinaldi WJ, Callebaut C, Blair W, Cihlar T, Geleziunas R, Yant SR, Barouch DH. Vidal SJ, et al. Nature. 2022 Jan;601(7894):612-616. doi: 10.1038/s41586-021-04279-4. Epub 2021 Dec 7. Nature. 2022. PMID: 34875675 Free PMC article.
Here we show that a single subcutaneous administration of GS-CA1 provides long-term protection against repeated rectal simian-human immunodeficiency virus (SHIV) challenges in rhesus macaques. ...
Here we show that a single subcutaneous administration of GS-CA1 provides long-term protection against repeated rectal simian-human i …
Pharmacological intervention of HIV-1 maturation.
Wang D, Lu W, Li F. Wang D, et al. Acta Pharm Sin B. 2015 Nov;5(6):493-9. doi: 10.1016/j.apsb.2015.05.004. Epub 2015 Jun 11. Acta Pharm Sin B. 2015. PMID: 26713265 Free PMC article. Review.
The Biodistribution of Replication-Defective Simian Adenovirus 1 Vector in a Mouse Model.
Chen J, Guo X, Zou X, Wang M, Yang C, Hou W, Sprindzuk MV, Lu Z. Chen J, et al. Viruses. 2024 Mar 31;16(4):550. doi: 10.3390/v16040550. Viruses. 2024. PMID: 38675893 Free PMC article.
The administration route affects the biodistribution of a gene transfer vector and the expression of a transgene. A simian adenovirus 1 vector carrying firefly luciferase and GFP reporter genes (SAdV1-GFluc) were constructed, and its biodistribution was investigated in a m …
The administration route affects the biodistribution of a gene transfer vector and the expression of a transgene. A simian adenovirus …
793 results