Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
2014 1
2020 1
2021 2
2022 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

8 results

Results by year

Filters applied: . Clear all
Page 1
New Insights into the Mechanism of Antibacterial Action of Synthetic Peptide Mo-CBP(3)-PepI against Klebsiella pneumoniae.
Branco LAC, Souza PFN, Neto NAS, Aguiar TKB, Silva AFB, Carneiro RF, Nagano CS, Mesquita FP, Lima LB, Freitas CDT. Branco LAC, et al. Antibiotics (Basel). 2022 Dec 4;11(12):1753. doi: 10.3390/antibiotics11121753. Antibiotics (Basel). 2022. PMID: 36551410 Free PMC article.
As such, synthetic peptides have emerged as potential alternative molecules. Mo-CBP(3)-PepI has presented great activity against K. pneumoniae by presenting an MIC(50) at a very low concentration (31.25 g mL(-1)). Here, fluorescence microscopy and proteomic analysis reveal …
As such, synthetic peptides have emerged as potential alternative molecules. Mo-CBP(3)-PepI has presented great activity against K. p …
JcTI-PepI, a synthetic peptide bioinspired in the trypsin inhibitor from Jatropha curcas, presents potent inhibitory activity against C. krusei, a neglected pathogen.
Souza LAL, Dias LP, Araújo NMS, Carneiro RF, Nagano CS, Teixeira CS, Silva RGG, Oliveira JTA, Sousa DOB. Souza LAL, et al. Biochimie. 2022 Sep;200:107-118. doi: 10.1016/j.biochi.2022.05.014. Epub 2022 May 24. Biochimie. 2022. PMID: 35623496
JcTI-PepI strongly inhibited C. krusei growth, and it caused severe disruptions in cellular processes and cell morphology. C. krusei cells treated with JcTI-PepI showed indicative of membrane permeabilization and overproduction of Reactive Oxygen Species. ...
JcTI-PepI strongly inhibited C. krusei growth, and it caused severe disruptions in cellular processes and cell morphology. C. krusei …
Synthetic antimicrobial peptides control Penicillium digitatum infection in orange fruits.
Lima PG, Freitas CDT, Oliveira JTA, Neto NAS, Amaral JL, Silva AFB, Sousa JS, Franco OL, Souza PFN. Lima PG, et al. Food Res Int. 2021 Sep;147:110582. doi: 10.1016/j.foodres.2021.110582. Epub 2021 Jul 1. Food Res Int. 2021. PMID: 34399551 Free article.
Interestingly, only three peptides (PepGAT, PepKAA, and Mo-CBP(3)-PepI) effectively control P. digitatum colonization in orange fruits, at a concentration (50 g mL(-1)) 20-fold lower than the commercial food preservative (sodium propionate). Altogether, PepGAT, PepKAA, and …
Interestingly, only three peptides (PepGAT, PepKAA, and Mo-CBP(3)-PepI) effectively control P. digitatum colonization in orange fruit …
Synergistic Antifungal Activity of Synthetic Peptides and Antifungal Drugs against Candida albicans and C. parapsilosis Biofilms.
Bezerra LP, Freitas CDT, Silva AFB, Amaral JL, Neto NAS, Silva RGG, Parra ALC, Goldman GH, Oliveira JTA, Mesquita FP, Souza PFN. Bezerra LP, et al. Antibiotics (Basel). 2022 Apr 21;11(5):553. doi: 10.3390/antibiotics11050553. Antibiotics (Basel). 2022. PMID: 35625197 Free PMC article.
Synthetic antimicrobial peptides (SAMPs) are considered to be new weapons to combat these infections, alone or combined with drugs. Here, two SAMPs, called Mo-CBP(3)-PepI and Mo-CBP(3)-PepIII, were tested alone or combined with nystatin (NYS) and itraconazole (ITR) against …
Synthetic antimicrobial peptides (SAMPs) are considered to be new weapons to combat these infections, alone or combined with drugs. Here, tw …
Real-world data on neoadjuvant endocrine therapy in ER-positive/HER2-negative breast cancer.
da Silva LR, de Andrade CA, Brenelli F, Ramalho S, Reinert T, de Souza ABA, da Silva AER, de Paula Leite Kraft MB, de Vasconcelos VCA, Frasson AL, Torresan RZ, Cabello C, Ellis MJ, Zeferino LC. da Silva LR, et al. Breast Cancer Res Treat. 2021 Apr;186(3):753-760. doi: 10.1007/s10549-020-06076-5. Epub 2021 Feb 4. Breast Cancer Res Treat. 2021. PMID: 33543355
Clinicopathological information were collected prospectively. Preoperative Endocrine Prognostic Index (PEPI) score was calculated for tumors submitted to at least 16 weeks of NET. ...Pathological complete response rate was 1.0%. 43 patients (29.5%) had PEPI score 0, …
Clinicopathological information were collected prospectively. Preoperative Endocrine Prognostic Index (PEPI) score was calculated for …
Sustained gene expression in the retina by improved episomal vectors.
Calado SM, Oliveira AV, Machado S, Haase R, Silva GA. Calado SM, et al. Tissue Eng Part A. 2014 Oct;20(19-20):2692-8. doi: 10.1089/ten.TEA.2013.0672. Epub 2014 May 9. Tissue Eng Part A. 2014. PMID: 24684370 Free PMC article.
The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be addressed. The pEPI-1 and pEPito family of vectors was developed to overcome these limitations. ...To achieve sustained gene delivery in …
The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be add …
ESR1 Mutations Are Not a Common Mechanism of Endocrine Resistance in Patients With Estrogen Receptor-Positive Breast Cancer Treated With Neoadjuvant Aromatase Inhibitor Therapy.
Reinert T, Ramalho S, de Vasconcelos VCA, Silva LR, da Silva AER, de Andrade CA, Kraft MBPL, Coelho GP, Mandelli J, Binotto M, Cabello C, de Paiva Silva GR, Bines J, Barrios CH, Ellis MJ, Graudenz MS. Reinert T, et al. Front Oncol. 2020 Apr 3;10:342. doi: 10.3389/fonc.2020.00342. eCollection 2020. Front Oncol. 2020. PMID: 32309212 Free PMC article.
Tumor samples from patients with a pattern of primary endocrine resistance [defined as a Preoperative Endocrine Prognostic Index (PEPI) score of 4] were identified and analyzed for the presence of ESR1m. Results: One hundred twenty-seven patients were included in the cohor …
Tumor samples from patients with a pattern of primary endocrine resistance [defined as a Preoperative Endocrine Prognostic Index (PEPI …
Cardiovascular hemodynamic interactions between clonidine and minoxidil in hypertensive patients.
Velasco M, Silva H, Morillo J, Urbina-Quintana A, Hernandez-Pieretti O, Angeli-Greaves M. Velasco M, et al. Chest. 1983 Feb;83(2 Suppl):360-4. doi: 10.1378/chest.83.2_supplement.360. Chest. 1983. PMID: 6337028
Clonidine in oral doses of 150 to 900 micrograms/day decreased mean blood pressure (MAP) 18.6 mm Hg (p less than 0.01), average heart rate (HR) 16.4 bpm (p less than 0.01), limb blood flow 1.63 ml/100 g min (p less than 0.05), plasma renin activity (PRA) 1.13 ng/ml/hr (p less tha …
Clonidine in oral doses of 150 to 900 micrograms/day decreased mean blood pressure (MAP) 18.6 mm Hg (p less than 0.01), average heart rate ( …