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Clinical efficacy of Shugan granule in the treatment of mixed anxiety-depressive disorder: A multicenter, randomized, double-blind, placebo-controlled trial.
Li Y, Li L, Guo R, Yu H, Wang X, Wang B, Wang Q, Li Z, Zhao H, Temu Q, Chen X, Zhang Y, An J, Cai X, Li A, Qi L, Shang J, He H, Yang D, Lin J, Zhang Y, Zou T. Li Y, et al. J Ethnopharmacol. 2022 May 23;290:115032. doi: 10.1016/j.jep.2022.115032. Epub 2022 Jan 25. J Ethnopharmacol. 2022. PMID: 35085742 Clinical Trial.
ETHNOPHARMACOLOGICAL RELEVANCE: Shugan granule is derived from Xiaoyao powder, a traditional Chinese medicine that has been shown to be effective in treating emotional disorders. ...Subjects in the test group (n = 200) received oral administration of Shugan granules …
ETHNOPHARMACOLOGICAL RELEVANCE: Shugan granule is derived from Xiaoyao powder, a traditional Chinese medicine that has been shown to …
Efficacy and safety of Shugan Jieyu capsule in the treatment of essential hypertension with insomnia, anxiety or depression: A protocol for systematic review and meta-analysis.
Fan M, Guo D, Tian Y, Liu Y, Zhao J. Fan M, et al. Medicine (Baltimore). 2021 Feb 26;100(8):e24856. doi: 10.1097/MD.0000000000024856. Medicine (Baltimore). 2021. PMID: 33663107 Free PMC article.
BACKGROUND: Shugan Jieyu capsule can reduce blood pressure and improve its concomitant symptoms. ...As a consequence, we provide a protocol to evaluate the efficacy and safety of Shugan Jieyu capsule (SJC) in the treatment of essential hypertension (EH) with insomni …
BACKGROUND: Shugan Jieyu capsule can reduce blood pressure and improve its concomitant symptoms. ...As a consequence, we provide a pr …
Network Pharmacology and Experimental Evidence: PI3K/AKT Signaling Pathway is Involved in the Antidepressive Roles of Chaihu Shugan San.
Zhang S, Lu Y, Chen W, Shi W, Zhao Q, Zhao J, Li L. Zhang S, et al. Drug Des Devel Ther. 2021 Aug 5;15:3425-3441. doi: 10.2147/DDDT.S315060. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 34385814 Free PMC article.
OBJECTIVE: Chaihu Shugan San (CSS) is a common antidepressant prescription in traditional Chinese medicines. ...
OBJECTIVE: Chaihu Shugan San (CSS) is a common antidepressant prescription in traditional Chinese medicines. ...
Shugan granule contributes to the improvement of depression-like behaviors in chronic restraint stress-stimulated rats by altering gut microbiota.
Li J, Li Y, Duan W, Zhao Z, Yang L, Wei W, Li J, Li Y, Yu Y, Dai B, Guo R. Li J, et al. CNS Neurosci Ther. 2022 Sep;28(9):1409-1424. doi: 10.1111/cns.13881. Epub 2022 Jun 17. CNS Neurosci Ther. 2022. PMID: 35713215 Free PMC article.
AIM: The investigation aims to evaluate the potential effect of Shugan Granule (SGKL) on the gut, brain, and behaviors in rats exposed to chronic restraint stress (CRS). ...
AIM: The investigation aims to evaluate the potential effect of Shugan Granule (SGKL) on the gut, brain, and behaviors in rats expose …
Improve cognition of depressive patients through the regulation of basal ganglia connectivity: Combined medication using Shuganjieyu capsule.
Liu S, Zhao W, Li Y, Li X, Li J, Cao H, Yang Z, Xu Y. Liu S, et al. J Psychiatr Res. 2020 Apr;123:39-47. doi: 10.1016/j.jpsychires.2020.01.013. Epub 2020 Jan 28. J Psychiatr Res. 2020. PMID: 32035307
Shuganjieyu capsule (Shugan) is a combined extract of Hypericum perforatum (HP) and Eleutherococcus senticosus (ES). ...A volume of the right caudate, which is increased in MMD, has also been reduced by Shugan treatment (P= 0.017). Importantly, the cognitive scores …
Shuganjieyu capsule (Shugan) is a combined extract of Hypericum perforatum (HP) and Eleutherococcus senticosus (ES). ...A volume of t …
Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation.
Lei S, Zhao S, Huang X, Feng Y, Li Z, Chen L, Huang P, Guan H, Zhang H, Wu Q, Chen B. Lei S, et al. Front Pharmacol. 2022 Sep 12;13:967623. doi: 10.3389/fphar.2022.967623. eCollection 2022. Front Pharmacol. 2022. PMID: 36172180 Free PMC article.
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic disease and is intertwined with cardiovascular disorders and diabetes. Chaihu Shugan powder (CSP) is a traditional Chinese medicine with a significant therapeutic effect on metabolic diseases …
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic disease and is intertwined with cardiovascular disorders a …
Shugan Hewei Decoction Alleviates Cecum Mucosal Injury and Improves Depressive- and Anxiety-Like Behaviors in Chronic Stress Model Rats by Regulating Cecal Microbiota and Inhibiting NLRP3 Inflammasome.
Yue Y, Chen Y, Liu H, Xu L, Zhou X, Ming H, Chen X, Chen M, Lin Y, Liu L, Zhao Y, Liu S. Yue Y, et al. Front Pharmacol. 2021 Dec 20;12:766474. doi: 10.3389/fphar.2021.766474. eCollection 2021. Front Pharmacol. 2021. PMID: 34987395 Free PMC article.
Gut microbiota disturbances are also associated with these disorders. Shugan Hewei Decoction (SHD), which is a traditional Chinese medicine formula developed by our team, has shown superior therapeutic effects in the treatment of depression, anxiety, and functional gastroi …
Gut microbiota disturbances are also associated with these disorders. Shugan Hewei Decoction (SHD), which is a traditional Chinese me …
SIRT1/FOXO1 Axis-Mediated Hippocampal Angiogenesis is Involved in the Antidepressant Effect of Chaihu Shugan San.
Zhang S, Lu Y, Shi W, Ren Y, Xiao K, Chen W, Li L, Zhao J. Zhang S, et al. Drug Des Devel Ther. 2022 Aug 23;16:2783-2801. doi: 10.2147/DDDT.S370825. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36039087 Free PMC article.
OBJECTIVE: Chaihu Shugan San (CSS) has a long history for treating major depressive disorder (MDD), which has been verified effectively and safely in clinical studies. ...
OBJECTIVE: Chaihu Shugan San (CSS) has a long history for treating major depressive disorder (MDD), which has been verified effective …
[Study on protective effect of Chaihu Shugan Powder against liver injury in rats with intrahepatic cholestasis by regulating FXR/Nrf2/ARE pathway].
Lou J, Zhao L, Zhu YJ, Yuan SQ, Wang F, Zhang HZ, Xu JJ, Yu XK, Hou LF. Lou J, et al. Zhongguo Zhong Yao Za Zhi. 2022 Oct;47(20):5610-5616. doi: 10.19540/j.cnki.cjcmm.20220519.401. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 36471979 Chinese.
This study aims to investigate the effect of Chaihu Shugan Powder(CHSG) on liver injury in rats with intrahepatic cholestasis by regulating farnesoid X receptor(FXR)/nuclear factor erythroid-2-related factor(Nrf2)/antioxidant response element(ARE) pathway. ...
This study aims to investigate the effect of Chaihu Shugan Powder(CHSG) on liver injury in rats with intrahepatic cholestasis by regu …
Tandem Mass Tag Analysis of the Effect of the Anterior Cingulate Cortex in Nonerosive Reflux Disease Rats with Shugan Jiangni Hewei Granules Treatment.
Wang T, Li J, Jia Y, Zhao J, He M, Bai G. Wang T, et al. Comput Math Methods Med. 2022 Jul 30;2022:8104337. doi: 10.1155/2022/8104337. eCollection 2022. Comput Math Methods Med. 2022. PMID: 35941898 Free PMC article.
OBJECTIVE: The current study aims to analyze the improvement mechanism of visceral hypersensitivity (VH) and targets of Shugan Jiangni Hewei granules (SJHG) for nonerosive reflux disease (NERD) treatment as well as to offer an experimental foundation for its clinical use. …
OBJECTIVE: The current study aims to analyze the improvement mechanism of visceral hypersensitivity (VH) and targets of Shugan Jiangn …
32 results