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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 5
2004 10
2005 17
2006 30
2007 34
2008 34
2009 63
2010 66
2011 86
2012 118
2013 111
2014 151
2015 150
2016 172
2017 164
2018 171
2019 185
2020 166
2021 139
2022 104
2023 111
2024 52

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1,874 results

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Page 1
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim H, Kim H, Feng Y, Li Y, Tamiya H, Tocci S, Ronai ZA. Kim H, et al. Sci Transl Med. 2020 Jul 8;12(551):eaaz5683. doi: 10.1126/scitranslmed.aaz5683. Sci Transl Med. 2020. PMID: 32641491 Free PMC article.
Increased expression of IFI204 and NLRC5 was associated with decreased melanoma growth in murine models, and increased expression of IFI16 and NLRC5 correlated with prolonged survival of patients with melanoma. Combination of pharmacological (GSK3326595) or genetic (shRNA) …
Increased expression of IFI204 and NLRC5 was associated with decreased melanoma growth in murine models, and increased expression of IFI16 a …
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice.
Tao W, Yurdagul A Jr, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. Tao W, et al. Sci Transl Med. 2020 Jul 22;12(553):eaay1063. doi: 10.1126/scitranslmed.aay1063. Sci Transl Med. 2020. PMID: 32718990 Free PMC article.
Atherosclerotic lesional macrophages express molecules that promote plaque progression, but lack of mechanisms to therapeutically target these molecules represents a major gap in translational cardiovascular research. Here, we tested the efficacy of a small interfering …
Atherosclerotic lesional macrophages express molecules that promote plaque progression, but lack of mechanisms to therapeutically target the …
Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.
Li Y, Chai JL, Shi X, Feng Y, Li JJ, Zhou LN, Cao C, Li KR. Li Y, et al. Theranostics. 2023 Apr 17;13(7):2319-2336. doi: 10.7150/thno.80749. eCollection 2023. Theranostics. 2023. PMID: 37153740 Free PMC article.
Netrin-1-induced human umbilical vein endothelial cell (HUVEC) proliferation, migration and tube formation were inhibited by Galphai1/3 short hairpin RNA (shRNA), but were potentiated by ectopic Galphai1/3 overexpression. In vivo, intravitreous injection of Netrin-1 …
Netrin-1-induced human umbilical vein endothelial cell (HUVEC) proliferation, migration and tube formation were inhibited by Galphai1/3 shor …
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines.
Zhang Y, Kong Y, Ma Y, Ni S, Wikerholmen T, Xi K, Zhao F, Zhao Z, Wang J, Huang B, Chen A, Yao Z, Han M, Feng Z, Hu Y, Thorsen F, Wang J, Li X. Zhang Y, et al. Oncogene. 2021 Feb;40(8):1425-1439. doi: 10.1038/s41388-020-01622-3. Epub 2021 Jan 8. Oncogene. 2021. PMID: 33420375 Free PMC article.
SiRNA knockdown of COPZ1 suppressed proliferation of U87MG, U251 and P3#GBM in vitro. Stable expression of a COPZ1 shRNA construct in U87MG inhibited tumor growth in vivo by ~60% relative to controls at day 21 after implantation (P < 0.001). ...
SiRNA knockdown of COPZ1 suppressed proliferation of U87MG, U251 and P3#GBM in vitro. Stable expression of a COPZ1 shRNA construct in …
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.
McDonald ER 3rd, de Weck A, Schlabach MR, Billy E, Mavrakis KJ, Hoffman GR, Belur D, Castelletti D, Frias E, Gampa K, Golji J, Kao I, Li L, Megel P, Perkins TA, Ramadan N, Ruddy DA, Silver SJ, Sovath S, Stump M, Weber O, Widmer R, Yu J, Yu K, Yue Y, Abramowski D, Ackley E, Barrett R, Berger J, Bernard JL, Billig R, Brachmann SM, Buxton F, Caothien R, Caushi JX, Chung FS, Cortés-Cros M, deBeaumont RS, Delaunay C, Desplat A, Duong W, Dwoske DA, Eldridge RS, Farsidjani A, Feng F, Feng J, Flemming D, Forrester W, Galli GG, Gao Z, Gauter F, Gibaja V, Haas K, Hattenberger M, Hood T, Hurov KE, Jagani Z, Jenal M, Johnson JA, Jones MD, Kapoor A, Korn J, Liu J, Liu Q, Liu S, Liu Y, Loo AT, Macchi KJ, Martin T, McAllister G, Meyer A, Mollé S, Pagliarini RA, Phadke T, Repko B, Schouwey T, Shanahan F, Shen Q, Stamm C, Stephan C, Stucke VM, Tiedt R, Varadarajan M, Venkatesan K, Vitari AC, Wallroth M, Weiler J, Zhang J, Mickanin C, Myer VE, Porter JA, Lai A, Bitter H, Lees E, Keen N, Kauffmann A, Stegmeier F, Hofmann F, Schmelzle T, Sellers WR. McDonald ER 3rd, et al. Cell. 2017 Jul 27;170(3):577-592.e10. doi: 10.1016/j.cell.2017.07.005. Cell. 2017. PMID: 28753431 Free article.
To identify vulnerabilities relevant to specific cancer subtypes, we conducted a large-scale RNAi screen in which viability effects of mRNA knockdown were assessed for 7,837 genes using an average of 20 shRNAs per gene in 398 cancer cell lines. We describe findings of this …
To identify vulnerabilities relevant to specific cancer subtypes, we conducted a large-scale RNAi screen in which viability effects of mRNA …
The OsSGS3-tasiRNA-OsARF3 module orchestrates abiotic-biotic stress response trade-off in rice.
Gu X, Si F, Feng Z, Li S, Liang D, Yang P, Yang C, Yan B, Tang J, Yang Y, Li T, Li L, Zhou J, Li J, Feng L, Liu JY, Yang Y, Deng Y, Wu XN, Zhao Z, Wan J, Cao X, Song X, He Z, Liu J. Gu X, et al. Nat Commun. 2023 Jul 24;14(1):4441. doi: 10.1038/s41467-023-40176-2. Nat Commun. 2023. PMID: 37488129 Free PMC article.
OsSGS3a interacts with its homolog OsSGS3b and modulates the biogenesis of trans-acting small interfering RNA (tasiRNA) targeting AUXIN RESPONSE FACTORS (ARFs). ...
OsSGS3a interacts with its homolog OsSGS3b and modulates the biogenesis of trans-acting small interfering RNA (tasiRNA) …
siRNA-based nanomedicine.
Zhao J, Mi Y, Feng SS. Zhao J, et al. Nanomedicine (Lond). 2013 Jun;8(6):859-62. doi: 10.2217/nnm.13.73. Nanomedicine (Lond). 2013. PMID: 23730692 Free article. No abstract available.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Chen F, Wang S, Zeng C, Tang S, Gu H, Wang Z, Li J, Feng P, Zhang Y, Wang P, Wu Y, Shen H. Chen F, et al. Cell Mol Life Sci. 2023 Oct 13;80(11):325. doi: 10.1007/s00018-023-04975-6. Cell Mol Life Sci. 2023. PMID: 37831180 Free PMC article.
CircSERPINE2 small interfering RNA delayed MSC senescence and rejuvenated MSCs, while circSERPINE2 overexpression had the opposite effect. RNA pulldown followed by mass spectrometry revealed an interaction between circSERPINE2 and YBX3. ...
CircSERPINE2 small interfering RNA delayed MSC senescence and rejuvenated MSCs, while circSERPINE2 overexpression had t …
1,874 results