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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2002 1
2003 2
2004 1
2007 1
2008 1
2009 1
2011 1
2014 1
2019 1
2020 1
2024 0

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12 results

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R409K mutation prevents acid-induced aggregation of human IgG4.
Namisaki H, Saito S, Hiraishi K, Haba T, Tanaka Y, Yoshida H, Iida S, Takahashi N. Namisaki H, et al. PLoS One. 2020 Mar 17;15(3):e0229027. doi: 10.1371/journal.pone.0229027. eCollection 2020. PLoS One. 2020. PMID: 32182240 Free PMC article.
By swapping the constant regions of IgG1 and IgG4, we determined that the constant heavy chain (CH3) domain is critical for aggregate formation, but a core-hinge-stabilizing S228P mutation in IgG4 is insufficient for preventing aggregation. To identify the aggregation-prone am …
By swapping the constant regions of IgG1 and IgG4, we determined that the constant heavy chain (CH3) domain is critical for aggregate format …
The C-terminal region affects the activity of photoactivated adenylyl cyclase from Oscillatoria acuminata.
Hirano M, Takebe M, Ishido T, Ide T, Matsunaga S. Hirano M, et al. Sci Rep. 2019 Dec 30;9(1):20262. doi: 10.1038/s41598-019-56721-3. Sci Rep. 2019. PMID: 31889099 Free PMC article.
We found that the photoactivity of OaPAC was inversely proportional to the C-terminal length. However, the deletion of more than nine amino acids did not further increase the activity, indicating that the nine amino acids at the C-terminal critically affect the phot …
We found that the photoactivity of OaPAC was inversely proportional to the C-terminal length. However, the deletion of more than nine ami …
Purification, characterization, and gene analysis of a chitosanase (ChoA) from Matsuebacter chitosanotabidus 3001.
Park JK, Shimono K, Ochiai N, Shigeru K, Kurita M, Ohta Y, Tanaka K, Matsuda H, Kawamukai M. Park JK, et al. J Bacteriol. 1999 Nov;181(21):6642-9. doi: 10.1128/JB.181.21.6642-6649.1999. J Bacteriol. 1999. PMID: 10542164 Free PMC article.
Sequencing of the choA gene revealed an open reading frame encoding a 391-amino-acid protein. The N-terminal amino acid sequence had an excretion signal, but the sequence did not show any significant homology to other proteins, including known chitosanases. The 80- …
Sequencing of the choA gene revealed an open reading frame encoding a 391-amino-acid protein. The N-terminal amino acid sequen …
Cloning and overexpression of an NADH-dependent alcohol dehydrogenase gene from Candida maris involved in (R)-selective reduction of 5-acetylfuro[2,3-c]pyridine.
Kawano S, Yano M, Hasegawa J, Yasohara Y. Kawano S, et al. Biosci Biotechnol Biochem. 2011;75(11):2155-61. doi: 10.1271/bbb.110453. Epub 2011 Nov 7. Biosci Biotechnol Biochem. 2011. PMID: 22056439 Free article.
The AFPDH gene comprises 762 bp and encodes a polypeptide of 27,230 Da. The deduced amino acid sequence showed a high degree of similarity to those of other members of the short-chain alcohol dehydrogenase superfamily. ...
The AFPDH gene comprises 762 bp and encodes a polypeptide of 27,230 Da. The deduced amino acid sequence showed a high degree of simil …
Inhibition of allergic dermal inflammation by the novel imidazopyridazine derivative TAK-427 in a guinea pig experimental model of eczema.
Fukuda S, Midoro K, Kamei T, Gyoten M, Kawano Y, Ashida Y, Nagaya H. Fukuda S, et al. J Pharmacol Exp Ther. 2002 Dec;303(3):1283-90. doi: 10.1124/jpet.102.040105. J Pharmacol Exp Ther. 2002. PMID: 12438553
Using such lesions as a model of eczema, we evaluated the potential value of TAK-427 [2-[6-[[3-[4-(diphenylmethoxy)piperidino]propyl]amino] imidazo[1,2-b]pyridazin-2-yl]-2-methylpropionic acid dihydrate] as a therapeutic agent for atopic dermatitis by comparing it with dex …
Using such lesions as a model of eczema, we evaluated the potential value of TAK-427 [2-[6-[[3-[4-(diphenylmethoxy)piperidino]propyl]amin …
Drug-drug interactions of Z-338, a novel gastroprokinetic agent, with terfenadine, comparison with cisapride, and involvement of UGT1A9 and 1A8 in the human metabolism of Z-338.
Furuta S, Kamada E, Omata T, Sugimoto T, Kawabata Y, Yonezawa K, Wu XC, Kurimoto T. Furuta S, et al. Eur J Pharmacol. 2004 Aug 23;497(2):223-31. doi: 10.1016/j.ejphar.2004.06.040. Eur J Pharmacol. 2004. PMID: 15306208
In the present study, the inhibitory properties of N-[2-(diisopropylamino)ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide monohydrochloride trihydrate (Z-338), a novel gastroprokinetic agent, were investigated and compared with those of cisaprid …
In the present study, the inhibitory properties of N-[2-(diisopropylamino)ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazo …
12 results