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Page 1
Bilirubin gates the TRPM2 channel as a direct agonist to exacerbate ischemic brain damage.
Neuron. 2023 May 17;111(10):1609-1625.e6. doi: 10.1016/j.neuron.2023.02.022. Epub 2023 Mar 14.
Neuron. 2023.
PMID: 36921602
Free PMC article.
Ca2+-dependent recruitment of voltage-gated sodium channels underlies bilirubin-induced overexcitation and neurotoxicity.
Shi HS, Lai K, Yin XL, Liang M, Ye HB, Shi HB, Wang LY, Yin SK.
Shi HS, et al.
Cell Death Dis. 2019 Oct 10;10(10):774. doi: 10.1038/s41419-019-1979-1.
Cell Death Dis. 2019.
PMID: 31601780
Free PMC article.
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Bilirubin enhances the activity of ASIC channels to exacerbate neurotoxicity in neonatal hyperbilirubinemia in mice.
Lai K, Song XL, Shi HS, Qi X, Li CY, Fang J, Wang F, Maximyuk O, Krishtal O, Xu TL, Li XY, Ni K, Li WP, Shi HB, Wang LY, Yin SK.
Lai K, et al. Among authors: shi hs.
Sci Transl Med. 2020 Feb 12;12(530):eaax1337. doi: 10.1126/scitranslmed.aax1337.
Sci Transl Med. 2020.
PMID: 32051225
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Bilirubin augments Ca2+ load of developing bushy neurons by targeting specific subtype of voltage-gated calcium channels.
Liang M, Yin XL, Shi HB, Li CY, Li XY, Song NY, Shi HS, Zhao Y, Wang LY, Yin SK.
Liang M, et al. Among authors: shi hs.
Sci Rep. 2017 Mar 27;7(1):431. doi: 10.1038/s41598-017-00275-9.
Sci Rep. 2017.
PMID: 28348377
Free PMC article.
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Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells.
Tang ZH, Chen JR, Zheng J, Shi HS, Ding J, Qian XD, Zhang C, Chen JL, Wang CC, Li L, Chen JZ, Yin SK, Huang TS, Chen P, Guan MX, Wang JF.
Tang ZH, et al. Among authors: shi hs.
Stem Cells Transl Med. 2016 May;5(5):561-71. doi: 10.5966/sctm.2015-0252. Epub 2016 Mar 24.
Stem Cells Transl Med. 2016.
PMID: 27013738
Free PMC article.
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