Design, synthesis, structural and molecular characterization, toxicity, psychotropic activity and molecular docking evaluation of a novel phenytoin derivative: 3-decyl-5,5-diphenylimidazolidine-2,4-dione.
Guerrab W, El Jemli M, Akachar J, Demirtaş G, Mague JT, Taoufik J, Ibrahimi A, Ansar M, Alaoui K, Ramli Y.
Guerrab W, et al.
J Biomol Struct Dyn. 2022;40(19):8765-8782. doi: 10.1080/07391102.2021.1922096. Epub 2021 May 10.
J Biomol Struct Dyn. 2022.
PMID: 33970810
HighlightsSynthesis, structural, and molecular characterization of a novel phenytoin derivative.DFT, XRD, and the Hirshfeld surface analysis of crystal structure was studied.Acute toxicity and psychotropic activity evaluation of 3-decyl-5,5 diphenylimidazolidine-2,4-dione (3DDID) …
HighlightsSynthesis, structural, and molecular characterization of a novel phenytoin derivative.DFT, XRD, and the Hirshfeld surface analysis …