Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice.
Sun L, Yong Y, Wei P, Wang Y, Li H, Zhou Y, Ruan W, Li X, Song J.
Sun L, et al.
CNS Neurosci Ther. 2022 Mar;28(3):390-400. doi: 10.1111/cns.13784. Epub 2021 Dec 23.
CNS Neurosci Ther. 2022.
PMID: 34951130
Free PMC article.
Mechanistically, the activation of NLRP3 inflammasome and NF-kappaB was inhibited by EA, while NLRP3 activation abolished EA's treatment effects on cognitive function. CONCLUSION: EA alleviates POCD-mediated cognitive dysfunction associated with ameliorated neuroinflammati …
Mechanistically, the activation of NLRP3 inflammasome and NF-kappaB was inhibited by EA, while NLRP3 activation abolished EA's treatm …