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Year Number of Results
1980 1
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2005 1
2006 1
2007 1
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2019 1
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2023 3
2024 0

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16 results

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Page 1
Possible Strategies to Mitigate Placebo or Vehicle Response in Dry Eye Disease Trials: A Narrative Review.
Montecchi-Palmer M, Wu M, Rolando M, Lau C, Perez Quinones VL, Dana R. Montecchi-Palmer M, et al. Ophthalmol Ther. 2023 Aug;12(4):1827-1849. doi: 10.1007/s40123-023-00720-1. Epub 2023 May 20. Ophthalmol Ther. 2023. PMID: 37208548 Free PMC article. Review.
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. ...
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs a …
DNA-Targeted NO Release Photoregulated by Green Light.
Parisi C, Fraix A, Guglielmo S, Spyrakis F, Rolando B, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Chemistry. 2020 Oct 27;26(60):13627-13633. doi: 10.1002/chem.202001538. Epub 2020 Sep 28. Chemistry. 2020. PMID: 32453464
These properties make the presented compound an intriguing candidate for fundamental and potential applicative research studies where NO delivery in the DNA proximity precisely regulated by harmless green light is required....
These properties make the presented compound an intriguing candidate for fundamental and potential applicative research studies where …
An intronic variant in the CELF4 gene is associated with risk for colorectal cancer.
Teerlink CC, Stevens J, Hernandez R, Facelli JC, Cannon-Albright LA. Teerlink CC, et al. Cancer Epidemiol. 2021 Jun;72:101941. doi: 10.1016/j.canep.2021.101941. Epub 2021 Apr 28. Cancer Epidemiol. 2021. PMID: 33930674 Free PMC article.
METHODS: DNA from two distantly related carriers of the hypothesized predisposition haplotype on 18q12.2 was sequenced to identify candidate variants. The candidate rare variants shared by the related sequenced subjects were screened in 3,094 CRC cases and 5x popula …
METHODS: DNA from two distantly related carriers of the hypothesized predisposition haplotype on 18q12.2 was sequenced to identify candid
NO-donor thiacarbocyanines as multifunctional agents for Alzheimer's disease.
Chegaev K, Federico A, Marini E, Rolando B, Fruttero R, Morbin M, Rossi G, Fugnanesi V, Bastone A, Salmona M, Badiola NB, Gasparini L, Cocco S, Ripoli C, Grassi C, Gasco A. Chegaev K, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4688-4698. doi: 10.1016/j.bmc.2015.05.050. Epub 2015 Jun 3. Bioorg Med Chem. 2015. PMID: 26078011 Free article.
Some symmetrical and unsymmetrical thiacarbocyanines bearing NO-donor nitrooxy and furoxan moieties were synthesized and studied as candidate anti-Alzheimer's drugs. All products activated soluble guanylate cyclase (sGC) in a dose-dependent manner, depending on the presenc …
Some symmetrical and unsymmetrical thiacarbocyanines bearing NO-donor nitrooxy and furoxan moieties were synthesized and studied as candi
Feasibility and reliability of comprehensive three-dimensional transoesophageal echocardiography screening process for transcatheter mitral valve replacement.
Piroli F, Boccellino A, Ingallina G, Rolando M, Melillo F, Ancona F, Stella S, Biondi F, Palmisano A, Esposito A, Denti P, Montorfano M, Maisano F, Castiglioni A, Agricola E. Piroli F, et al. Eur Heart J Cardiovasc Imaging. 2023 Jul 24;24(8):1043-1051. doi: 10.1093/ehjci/jead015. Eur Heart J Cardiovasc Imaging. 2023. PMID: 36797650 Free PMC article.
We evaluated the feasibility and reliability of a comprehensive 3D-TOE screening in TMVR candidates. METHODS AND RESULTS: We performed a retrospective observational study including 72 consecutive patients who underwent a pre-procedural CT and 3D-TOE for TMVR evaluation. .. …
We evaluated the feasibility and reliability of a comprehensive 3D-TOE screening in TMVR candidates. METHODS AND RESULTS: We performe …
A preliminary report of a randomized controlled phase 2 trial of the safety and immunogenicity of mRNA-1273 SARS-CoV-2 vaccine.
Chu L, McPhee R, Huang W, Bennett H, Pajon R, Nestorova B, Leav B; mRNA-1273 Study Group. Chu L, et al. Vaccine. 2021 May 12;39(20):2791-2799. doi: 10.1016/j.vaccine.2021.02.007. Epub 2021 Feb 9. Vaccine. 2021. PMID: 33707061 Free PMC article. Clinical Trial.
BACKGROUND: Vaccines are urgently needed to prevent the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We assessed the safety and immunogenicity of vaccine candidate mRNA-1273, encoding the prefusion-stabilized spike protein of SARS-CoV-2. . …
BACKGROUND: Vaccines are urgently needed to prevent the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We as …
Screening for active and latent tuberculosis among asylum seekers in Italy: A retrospective cohort analysis.
Pontarelli A, Marchese V, Scolari C, Capone S, El-Hamad I, Donato F, Moioli R, Girardi E, Cirillo DM, Castelli F, Matteelli A. Pontarelli A, et al. Travel Med Infect Dis. 2019 Jan-Feb;27:39-45. doi: 10.1016/j.tmaid.2018.10.015. Epub 2018 Oct 19. Travel Med Infect Dis. 2019. PMID: 30347248
Of 2303 (89.7%) AS with TST result, the positivity rate was 36.6% (843/2303). Of the 843 candidates for LTBI treatment 413 (49.0%) completed the screening. LTBI treatment was prescribed to 190 (47.9%) of 397 eligible individuals, 10.8% (91) completed treatment. ...
Of 2303 (89.7%) AS with TST result, the positivity rate was 36.6% (843/2303). Of the 843 candidates for LTBI treatment 413 (49.0%) co …
Identification of potential antiviral compounds against SARS-CoV-2 structural and non structural protein targets: A pharmacoinformatics study of the CAS COVID-19 dataset.
García R, Hussain A, Koduru P, Atis M, Wilson K, Park JY, Toby I, Diwa K, Vu L, Ho S, Adnan F, Nguyen A, Cox A, Kirtek T, García P, Li Y, Jones H, Shi G, Green A, Rosenbaum D. García R, et al. Comput Biol Med. 2021 Jun;133:104364. doi: 10.1016/j.compbiomed.2021.104364. Epub 2021 Apr 19. Comput Biol Med. 2021. PMID: 33895457 Free PMC article.
The pharmacological profiles of these compounds showed potential drug-likeness properties. Our work provides a list of candidate anti-viral compounds that may be used as a guide for further investigation and therapeutic development against SARS-CoV-2....
The pharmacological profiles of these compounds showed potential drug-likeness properties. Our work provides a list of candidate anti …
Polymorphism of the GHR gene in cattle and relationships with meat production and quality.
Di Stasio L, Destefanis G, Brugiapaglia A, Albera A, Rolando A. Di Stasio L, et al. Anim Genet. 2005 Apr;36(2):138-40. doi: 10.1111/j.1365-2052.2005.01244.x. Anim Genet. 2005. PMID: 15771724
Growth hormone (GH) exerts its effects on growth and metabolism by interacting with a specific receptor (GHR) on the surface of the target cells. Therefore, GHR has been suggested as candidate gene for traits related to meat production in cattle. The aim of the study was t …
Growth hormone (GH) exerts its effects on growth and metabolism by interacting with a specific receptor (GHR) on the surface of the target c …
16 results