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Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial.
Cortes J, Cescon DW, Rugo HS, Nowecki Z, Im SA, Yusof MM, Gallardo C, Lipatov O, Barrios CH, Holgado E, Iwata H, Masuda N, Otero MT, Gokmen E, Loi S, Guo Z, Zhao J, Aktan G, Karantza V, Schmid P; KEYNOTE-355 Investigators. Cortes J, et al. Lancet. 2020 Dec 5;396(10265):1817-1828. doi: 10.1016/S0140-6736(20)32531-9. Lancet. 2020. PMID: 33278935 Clinical Trial.
METHODS: In this randomised, placebo-controlled, double-blind, phase 3 trial, done in 209 sites in 29 countries, we randomly assigned patients 2:1 with untreated locally recurrent inoperable or metastatic triple-negative breast cancer using a block method (block size of six) and …
METHODS: In this randomised, placebo-controlled, double-blind, phase 3 trial, done in 209 sites in 29 countries, we randomly assigned patien …
CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes.
Schnell O, Battelino T, Bergenstal R, Birkenfeld AL, Ceriello A, Cheng A, Davies M, Edelman S, Forst T, Giorgino F, Green J, Groop PH, Hadjadj S, J L Heerspink H, Hompesch M, Izthak B, Ji L, Kanumilli N, Mankovsky B, Mathieu C, Miszon M, Mustafa R, Nauck M, Pecoits-Filho R, Pettus J, Ranta K, Rodbard HW, Rossing P, Ryden L, Schumm-Draeger PM, Solomon SD, Škrha J, Topsever P, Vilsbøll T, Wilding J, Standl E. Schnell O, et al. Cardiovasc Diabetol. 2023 Mar 16;22(1):59. doi: 10.1186/s12933-023-01788-6. Cardiovasc Diabetol. 2023. PMID: 36927451 Free PMC article.
Blindness influences emotional authenticity perception in voices: Behavioral and ERP evidence.
Sarzedas J, Lima CF, Roberto MS, Scott SK, Pinheiro AP, Conde T. Sarzedas J, et al. Cortex. 2024 Mar;172:254-270. doi: 10.1016/j.cortex.2023.11.005. Epub 2023 Nov 28. Cortex. 2024. PMID: 38123404 Free article.
Altogether, these findings suggest that early blindness relates to facilitated brain processing of authenticity in voices, both at early sensory and late cognitive-evaluative stages. ...
Altogether, these findings suggest that early blindness relates to facilitated brain processing of authenticity in voices, both at ea …
Young Neurosurgeons Committee of the American Association of Neurological Surgeons: Training Ground for Future Leaders in Organized Neurosurgery in the United States of America.
Linzey JR, Sivakumar W, Johnson JN, Ivan ME, Haider AS, Philips CA, Than KD, Tomei KL, Muraszko KM, Nduom EK. Linzey JR, et al. World Neurosurg. 2019 Mar;123:59-63. doi: 10.1016/j.wneu.2018.11.206. Epub 2018 Dec 7. World Neurosurg. 2019. PMID: 30529528 Free PMC article. Review.
The Young Neurosurgeons Committee, founded in 1991 by Dr. Roberto C. Heros, has been a vital component of the American Association of Neurological Surgeons. It has grown from an opportunity for young neurosurgeons to network with senior neurosurgeons to becoming the major …
The Young Neurosurgeons Committee, founded in 1991 by Dr. Roberto C. Heros, has been a vital component of the American Association of …
Attention and emotion shape self-voice prioritization in speech processing.
Pinheiro AP, Sarzedas J, Roberto MS, Kotz SA. Pinheiro AP, et al. Cortex. 2023 Jan;158:83-95. doi: 10.1016/j.cortex.2022.10.006. Epub 2022 Oct 26. Cortex. 2023. PMID: 36473276
Both self-voice and emotional speech are salient signals that are prioritized in perception. Surprisingly, self-voice perception has been investigated to a lesser extent than the self-face. ...
Both self-voice and emotional speech are salient signals that are prioritized in perception. Surprisingly, self-voice percepti …
Self-voice perception and its relationship with hallucination predisposition.
Pinheiro AP, Farinha-Fernandes A, Roberto MS, Kotz SA. Pinheiro AP, et al. Cogn Neuropsychiatry. 2019 Jul;24(4):237-255. doi: 10.1080/13546805.2019.1621159. Epub 2019 Jun 10. Cogn Neuropsychiatry. 2019. PMID: 31177920
However, whether self-voice processing is also affected in nonclinical voice hearers remains to be specified. ...Specific alterations in self-voice perception in clinical and nonclinical voice hearers may establish a core feature of the psychosis conti …
However, whether self-voice processing is also affected in nonclinical voice hearers remains to be specified. ...Specific alte …
The perceived salience of vocal emotions is dampened in non-clinical auditory verbal hallucinations.
Amorim M, Roberto MS, Kotz SA, Pinheiro AP. Amorim M, et al. Cogn Neuropsychiatry. 2022 Mar-May;27(2-3):169-182. doi: 10.1080/13546805.2021.1949972. Epub 2021 Jul 14. Cogn Neuropsychiatry. 2022. PMID: 34261424
Previous evidence suggests that AVH may reflect an imbalance of prior expectation and sensory information, and that altered salience processing is characteristic of both psychotic and non-clinical voice hearers. However, it remains to be shown how such an imbalance affects …
Previous evidence suggests that AVH may reflect an imbalance of prior expectation and sensory information, and that altered salience process …
Characterization of Dermatoglyphic Profiles and its Relation to Acoustic Measures in Voice Professionals.
Santana ÉR, Oliveira P, Magacho-Coelho C, Lopes L, Sacramento LSC. Santana ÉR, et al. J Voice. 2023 Nov;37(6):967.e1-967.e7. doi: 10.1016/j.jvoice.2021.06.006. Epub 2021 Jul 10. J Voice. 2023. PMID: 34256980
OBJECTIVE: To characterize the dermatoglyphic profiles and their relation to acoustic measures in voice professionals. METHODS: A cross-sectional study involving 79 voice professionals. ...Dermatoglyphics could have been seen as an interesting tool in the voice …
OBJECTIVE: To characterize the dermatoglyphic profiles and their relation to acoustic measures in voice professionals. METHODS: A cro …
Automatized FACEmemory® scoring is related to Alzheimer's disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort.
Alegret M, Sotolongo-Grau O, de Antonio EE, Pérez-Cordón A, Orellana A, Espinosa A, Gil S, Jiménez D, Ortega G, Sanabria A, Roberto N, Hernández I, Rosende-Roca M, Tartari JP, Alarcon-Martin E, de Rojas I, Montrreal L, Morató X, Cano A, Rentz DM, Tárraga L, Ruiz A, Valero S, Marquié M, Boada M. Alegret M, et al. Alzheimers Res Ther. 2022 Mar 18;14(1):43. doi: 10.1186/s13195-022-00988-8. Alzheimers Res Ther. 2022. PMID: 35303916 Free PMC article.
BACKGROUND: FACEmemory is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors. ...
BACKGROUND: FACEmemory is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be con …
21 results