Mesenchymal stromal cells loaded with Paclitaxel (PacliMES) a potential new therapeutic approach on mesothelioma.
Coccè V, Bonelli M, La Monica S, Alfieri R, Doneda L, Martegani E, Alessandri G, Lagrasta CA, Giannì A, Sordi V, Petrella F, Roncoroni L, Paino F, Pessina A.
Coccè V, et al.
Biochem Pharmacol. 2023 Aug;214:115678. doi: 10.1016/j.bcp.2023.115678. Epub 2023 Jul 1.
Biochem Pharmacol. 2023.
PMID: 37399948
Free article.
The present study confirms that Paclitaxel is effective on mesothelioma cell proliferation in 2D and 3D in vitro cultures, and that 80,000 mesenchymal stromal cells loaded with Paclitaxel inhibit tumor growth at a higher extent than Paclitaxel alone. An in vivo approach to …
The present study confirms that Paclitaxel is effective on mesothelioma cell proliferation in 2D and 3D in vitro cultures, and that 80,000 m …