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Year Number of Results
1954 1
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1961 1
1962 1
1963 1
1964 5
1965 3
1966 2
1967 2
1968 6
1969 6
1970 7
1971 6
1972 8
1973 4
1974 5
1975 124
1976 71
1977 40
1978 64
1979 67
1980 95
1981 110
1982 161
1983 214
1984 241
1985 264
1986 347
1987 327
1988 354
1989 317
1990 387
1991 390
1992 403
1993 406
1994 415
1995 509
1996 555
1997 401
1998 416
1999 392
2000 415
2001 372
2002 335
2003 373
2004 334
2005 376
2006 370
2007 334
2008 339
2009 340
2010 328
2011 342
2012 346
2013 415
2014 421
2015 360
2016 351
2017 373
2018 341
2019 330
2020 348
2021 306
2022 272
2023 263
2024 109

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14,644 results

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Page 1
Curcumin attenuates morphine dependence by modulating mu-opioid receptors and glial cell-activated neuroinflammation in rat.
Sheikholeslami MA, Parvardeh S, Ghafghazi S, Sabetkasaei M. Sheikholeslami MA, et al. Neuropeptides. 2023 Apr;98:102318. doi: 10.1016/j.npep.2022.102318. Epub 2022 Dec 29. Neuropeptides. 2023. PMID: 36640553
The main goal of this study was to explore the attenuating effects of curcumin on morphine dependence with a focus on neuroinflammation and mu-opioid receptors in the rat prefrontal cortex. To induce morphine dependence in male Wistar rats, morphine was admin …
The main goal of this study was to explore the attenuating effects of curcumin on morphine dependence with a focus on neuroinflammation and …
Chronic developmental lead exposure increases mu-opiate receptor levels in the adolescent rat brain.
Albores-Garcia D, McGlothan JL, Bursac Z, Guilarte TR. Albores-Garcia D, et al. Neurotoxicology. 2021 Jan;82:119-129. doi: 10.1016/j.neuro.2020.11.008. Epub 2020 Nov 25. Neurotoxicology. 2021. PMID: 33248188 Free PMC article.
In this study, we examine the effect of chronic developmental Pb(2+) exposure (1500 ppm in the diet) on mu-opioid receptor (MOR) levels in the rat brain using [(3)H]-d-Ala2-MePhe4-Gly-ol5 enkephalin ([(3)H]-DAMGO) quantitative receptor autoradiography at different d …
In this study, we examine the effect of chronic developmental Pb(2+) exposure (1500 ppm in the diet) on mu-opioid receptor (MOR) leve …
mu Opiate receptor immunoreactivity in rat central nervous system.
Moriwaki A, Wang JB, Svingos A, van Bockstaele E, Cheng P, Pickel V, Uhl GR. Moriwaki A, et al. Neurochem Res. 1996 Nov;21(11):1315-31. doi: 10.1007/BF02532373. Neurochem Res. 1996. PMID: 8947922
Immunoreactivity corresponding to the C-terminus of the rat mu opiate receptor can be detected by light microscopy in fiber- and terminal-like patterns in a number of rat brain and spinal cord regions, and in immunoreactive perikarya in several of these regio …
Immunoreactivity corresponding to the C-terminus of the rat mu opiate receptor can be detected by light microscopy in fiber- a …
Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state.
Ferdousi MI, Calcagno P, Clarke M, Aggarwal S, Sanchez C, Smith KL, Eyerman DJ, Kelly JP, Roche M, Finn DP. Ferdousi MI, et al. Pain. 2021 Feb 1;162(2):405-420. doi: 10.1097/j.pain.0000000000002039. Pain. 2021. PMID: 32826755
The inbred Wistar-Kyoto (WKY) rat, which mimics aspects of anxiety and depression, displays increased sensitivity (hyperalgesia) to noxious stimuli, compared with Sprague-Dawley (SD) rats. ...Although MOP expression in the ventrolateral periaqueductal gray (vlPAG) d …
The inbred Wistar-Kyoto (WKY) rat, which mimics aspects of anxiety and depression, displays increased sensitivity (hyperalgesia) to n …
Role of Glial Cells in mu-Opioid Receptor-Mediated Vasodilation in the Rat Retina.
Someya E, Mori A, Asano D, Morita A, Sakamoto K, Nakahara T. Someya E, et al. Curr Eye Res. 2018 Mar;43(3):350-356. doi: 10.1080/02713683.2017.1403631. Epub 2017 Nov 27. Curr Eye Res. 2018. PMID: 29172736
PURPOSE: Our recent study demonstrated that herkinorin, a non-opioid mu-receptor agonist derived from salvinorin A, dilates retinal arterioles through stimulation of mu-opioid receptors in rats. ...MATERIALS AND METHODS: The localization of mu-opioid r …
PURPOSE: Our recent study demonstrated that herkinorin, a non-opioid mu-receptor agonist derived from salvinorin A, dilates retinal a …
Enhancement of mu-opioid receptor desensitization by orexin-A in rat locus coeruleus neurons.
Mohammad Ahmadi Soleimani S, Azizi H, Pachenari N, Mirnajafi-Zadeh J, Semnanian S. Mohammad Ahmadi Soleimani S, et al. Neuropeptides. 2017 Jun;63:28-36. doi: 10.1016/j.npep.2017.03.004. Epub 2017 Mar 23. Neuropeptides. 2017. PMID: 28385341
However, development of tolerance to their effects following long term administration, seriously restricts further clinical use of these drugs. In this regard, mu-opioid receptor (MOR) desensitization, as an initial step in development of opioid tolerance, is of particular …
However, development of tolerance to their effects following long term administration, seriously restricts further clinical use of these dru …
mu Receptors and opioid cardiovascular effects in the NTS of rat.
Hassen AH, Feuerstein G, Faden AI. Hassen AH, et al. Peptides. 1982 Nov-Dec;3(6):1031-7. doi: 10.1016/0196-9781(82)90074-2. Peptides. 1982. PMID: 6300804
In order to assess the potential role of mu (mu) and delta (delta) opiate receptors in the central regulation of the cardiovascular and respiratory systems, the cardiovascular and respiratory effects of the relatively selective mu-opioid agonist D-Ala2, MePhe …
In order to assess the potential role of mu (mu) and delta (delta) opiate receptors in the central regulation of the cardiovas …
Social Novelty Investigation in the Juvenile Rat: Modulation by the mu-Opioid System.
Smith CJ, Wilkins KB, Mogavero JN, Veenema AH. Smith CJ, et al. J Neuroendocrinol. 2015 Oct;27(10):752-64. doi: 10.1111/jne.12301. J Neuroendocrinol. 2015. PMID: 26212131
To this end, we developed the social novelty preference test to assess the preference of a juvenile rat to investigate a novel over a familiar (cage mate) conspecific. ...Overall, we have established a new behavioural test to study social novelty-seeking behaviour in the j …
To this end, we developed the social novelty preference test to assess the preference of a juvenile rat to investigate a novel over a …
Immunohistochemical localization of mu-opioid receptors in the central nervous system of the rat.
Ding YQ, Kaneko T, Nomura S, Mizuno N. Ding YQ, et al. J Comp Neurol. 1996 Apr 8;367(3):375-402. doi: 10.1002/(SICI)1096-9861(19960408)367:3<375::AID-CNE5>3.0.CO;2-2. J Comp Neurol. 1996. PMID: 8698899
Of the three major types of opioid receptors ( mu, delta, kappa) in the nervous system, mu-opioid receptor shows the highest affinity for morphine that exerts powerful effects on nociceptive, autonomic, and psychological functions. So far, at least two isoforms of …
Of the three major types of opioid receptors ( mu, delta, kappa) in the nervous system, mu-opioid receptor shows the highest a …
Modeling hypoglossal motoneurons in the developing rat.
Williams PA, Dalton C, Wilson CG. Williams PA, et al. Respir Physiol Neurobiol. 2019 Jul;265:40-48. doi: 10.1016/j.resp.2018.07.009. Epub 2018 Jul 26. Respir Physiol Neurobiol. 2019. PMID: 30056243
We used the Golgi-Cox technique to stain developing hypoglossal motoneurons (XII MNs) at three postnatal ages (P3, 10, & 17). We removed Sprague-Dawley rat pup brains, processed, sectioned, stained, imaged, and performed 3D reconstructions to quantify the morphometrics …
We used the Golgi-Cox technique to stain developing hypoglossal motoneurons (XII MNs) at three postnatal ages (P3, 10, & 17). We removed …
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