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Lipophilic oligonucleotides spontaneously insert into lipid membranes, bind complementary DNA strands, and sequester into lipid-disordered domains.
Bunge A, Kurz A, Windeck AK, Korte T, Flasche W, Liebscher J, Herrmann A, Huster D. Bunge A, et al. Langmuir. 2007 Apr 10;23(8):4455-64. doi: 10.1021/la063188u. Epub 2007 Mar 17. Langmuir. 2007. PMID: 17367171
Further, the membrane bound DNA double strands also undergo regular melting. Finally, in raft-like membrane mixtures, the lipophilic oligonucleotide was shown to preferentially sequester into liquid-disordered membrane domains....
Further, the membrane bound DNA double strands also undergo regular melting. Finally, in raft-like membrane mixtures, the lipophilic …
Functional and molecular alterations in T Cells induced by CCL5.
Cridge TJ, Horowitz KM, Marinucci MN, Rose KM, Wells M, Werner MT, Kurt RA. Cridge TJ, et al. Immunol Invest. 2006;35(1):115-32. doi: 10.1080/08820130500514365. Immunol Invest. 2006. PMID: 16531333
To identify a mechanism by which CCL5 modulated T cell function, we examined T cell receptor translocation and lipid raft clustering. After exposure to CCL5, T cells were less efficient at translocating the TCR and clustering lipid rafts. Since TCR translocation and lipid …
To identify a mechanism by which CCL5 modulated T cell function, we examined T cell receptor translocation and lipid raft clustering. …
Orthogonal Modification of Polymers via Thio-Bromo "Click" Reaction and Supramolecular Chemistry: An Easy Method Toward Head-to-Tail Self-Assembled Supramolecular Polymers.
Chen S, Ströhl D, Binder WH. Chen S, et al. ACS Macro Lett. 2015 Jan 20;4(1):48-52. doi: 10.1021/mz500747t. Epub 2014 Dec 22. ACS Macro Lett. 2015. PMID: 35596371
Heterotelechelic poly(n-butyl acrylate)s (PnBuA) bearing two different and complementing supramolecular groups (namely, barbiturate (Ba) and the Hamilton wedge (HW)) at their alpha-end and omega-end (Ba-PnBuA-HW) were prepared by a combination of the reversible addition-fragmenta …
Heterotelechelic poly(n-butyl acrylate)s (PnBuA) bearing two different and complementing supramolecular groups (namely, barbiturate (Ba) and …