Selected alpha-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro.
Herath HMPD, Preston S, Jabbar A, Garcia-Bustos J, Addison RS, Hayes S, Rali T, Wang T, Koehler AV, Chang BCH, Hofmann A, Davis RA, Gasser RB.
Herath HMPD, et al.
Int J Parasitol Drugs Drug Resist. 2019 Apr;9:72-79. doi: 10.1016/j.ijpddr.2018.12.006. Epub 2019 Jan 4.
Int J Parasitol Drugs Drug Resist. 2019.
PMID: 30739078
Free PMC article.
Subsequently, compounds were purified from fractions with significant biological activity. Four alpha-pyrones, namely goniothalamin (GNT), dihydrokavain (DHK), desmethoxyyangonin (DMY) and yangonin (YGN), were purified from fractions from the two plants, GNT from C. novogu …
Subsequently, compounds were purified from fractions with significant biological activity. Four alpha-pyrones, namely goniothalamin ( …