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The Pediatric Optic Neuritis Prospective Outcomes Study: Two-Year Results.
Pineles SL, Henderson RJ, Repka MX, Heidary G, Liu GT, Waldman AT, Borchert MS, Khanna S, Graves JS, Collinge JE, Conley JA, Davis PL, Kraker RT, Cotter SA, Holmes JM; Pediatric Eye Disease Investigator Group. Pineles SL, et al. Ophthalmology. 2022 Aug;129(8):856-864. doi: 10.1016/j.ophtha.2022.03.021. Epub 2022 Mar 29. Ophthalmology. 2022. PMID: 35364222 Free PMC article.
The Pediatric ON Prospective Outcomes Study (PON1) was the first prospective study to our knowledge aiming to evaluate visual acuity (VA) outcomes, including VA, recurrence risk, and final diagnosis 2 years after enrollment. ...Mean presenting LCVA was 1.45 logMAR ( …
The Pediatric ON Prospective Outcomes Study (PON1) was the first prospective study to our knowledge aiming to evaluate visual acuity (VA …
Real-world Effectiveness of Azacitidine in Treatment-Naive Patients With Higher-risk Myelodysplastic Syndromes.
Rajakumaraswamy N, Gandhi M, Wei AH, Sallman DA, Daver NG, Mo S, Iqbal S, Karalliyadda R, Chen M, Wang Y, Vyas P. Rajakumaraswamy N, et al. Clin Lymphoma Myeloma Leuk. 2024 Apr;24(4):260-268.e2. doi: 10.1016/j.clml.2023.12.008. Epub 2023 Dec 20. Clin Lymphoma Myeloma Leuk. 2024. PMID: 38216397 Free article.
INTRODUCTION: Azacitidine (AZA) is an approved frontline therapy for higher-risk myelodysplastic syndromes (HR-MDS); however, poor survival denotes unmet needs to increase depth/duration of response (DOR). ...RESULTS: Using IWG 2006 criteria, the CRR was 7.9% (n = 30); med …
INTRODUCTION: Azacitidine (AZA) is an approved frontline therapy for higher-risk myelodysplastic syndromes (HR-MDS); however, poor su …
Metabolomics and Self-Reported Depression, Anxiety, and Phobic Symptoms in the VA Normative Aging Study.
Prince N, Stav M, Cote M, Chu SH, Vyas CM, Okereke OI, Palacios N, Litonjua AA, Vokonas P, Sparrow D, Spiro A 3rd, Lasky-Su JA, Kelly RS. Prince N, et al. Metabolites. 2023 Jul 15;13(7):851. doi: 10.3390/metabo13070851. Metabolites. 2023. PMID: 37512558 Free PMC article.
Furthermore, three of these four metabolites demonstrated a higher degree of alteration in men who reported poor scores in all three dimensions compared to men with poor scores in only one, suggesting the potential for shared underlying biology but a differing degre …
Furthermore, three of these four metabolites demonstrated a higher degree of alteration in men who reported poor scores in all three …
Loss of consciousness at onset of aneurysmal subarachnoid hemorrhage in good-grade patients.
Hendrix P, Foreman PM, Senger S, Burkhardt BW, Harrigan MR, Fisher WS 3rd, Vyas NA, Lipsky RH, Walters BC, Tubbs RS, Shoja MM, Griessenauer CJ. Hendrix P, et al. Neurosurg Rev. 2020 Aug;43(4):1173-1178. doi: 10.1007/s10143-019-01142-z. Epub 2019 Jul 22. Neurosurg Rev. 2020. PMID: 31332702
Loss of consciousness (LOC) at presentation with aneurysmal subarachnoid hemorrhage (aSAH) has been associated with early brain injury and poor functional outcome. The impact of LOC on the clinical course after aSAH deserves further exploration. ...
Loss of consciousness (LOC) at presentation with aneurysmal subarachnoid hemorrhage (aSAH) has been associated with early brain injury and …
PHASES score applied to a prospective cohort of aneurysmal subarachnoid hemorrhage patients.
Foreman PM, Hendrix P, Harrigan MR, Fisher WS 3rd, Vyas NA, Lipsky RH, Walters BC, Tubbs RS, Shoja MM, Griessenauer CJ. Foreman PM, et al. J Clin Neurosci. 2018 Jul;53:69-73. doi: 10.1016/j.jocn.2018.04.014. Epub 2018 Apr 20. J Clin Neurosci. 2018. PMID: 29685416
Multivariable modeling identified higher PHASES scores (OR 1.235, CI 1.016-1.501, p = 0.034) and higher Hunt and Hess grades (OR 2.224, CI 1.353-3.655, p = 0.002) as independent predictors of poor functional outcome (mRS 3-6) at last follow up. The majority of aSAH patient …
Multivariable modeling identified higher PHASES scores (OR 1.235, CI 1.016-1.501, p = 0.034) and higher Hunt and Hess grades (OR 2.224, CI 1 …
Endothelin polymorphisms as a risk factor for cerebral aneurysm rebleeding following aneurysmal subarachnoid hemorrhage.
Foreman PM, Starke RM, Hendrix P, Harrigan MR, Fisher WS Rd, Vyas NA, Lipsky RH, Lin M, Walters BC, Pittet JF, Mathru M, Griessenauer CJ. Foreman PM, et al. Clin Neurol Neurosurg. 2017 Jun;157:65-69. doi: 10.1016/j.clineuro.2017.04.007. Epub 2017 Apr 7. Clin Neurol Neurosurg. 2017. PMID: 28412541
BACKGROUND: Aneurysm rebleeding following presentation with aneurysmal subarachnoid hemorrhage (aSAH) is associated with high mortality and poor functional outcome. While a substantial genetic contribution to aneurysm formation and rupture is known, the genetic influence o …
BACKGROUND: Aneurysm rebleeding following presentation with aneurysmal subarachnoid hemorrhage (aSAH) is associated with high mortality and …
The Florida Pancreas Collaborative Next-Generation Biobank: Infrastructure to Reduce Disparities and Improve Survival for a Diverse Cohort of Patients with Pancreatic Cancer.
Permuth JB, Dezsi KB, Vyas S, Ali KN, Basinski TL, Utuama OA, Denbo JW, Klapman J, Dam A, Carballido E, Kim DW, Pimiento JM, Powers BD, Otto AK, Choi JW, Chen DT, Teer JK, Beato F, Ward A, Cortizas EM, Whisner SY, Williams IE, Riner AN, Tardif K, Velanovich V, Karachristos A, Douglas WG, Legaspi A, Allan BJ, Meredith K, Molina-Vega MA, Bao P, St Julien J, Huguet KL, Green L, Odedina FT, Kumar NB, Simmons VN, George TJ, Vadaparampil ST, Hodul PJ, Arnoletti JP, Awad ZT, Bose D, Jiang K, Centeno BA, Gwede CK, Malafa M, Judge SM, Judge AR, Jeong D, Bloomston M, Merchant NB, Fleming JB, Trevino JG, On Behalf Of The Florida Pancreas Collaborative. Permuth JB, et al. Cancers (Basel). 2021 Feb 15;13(4):809. doi: 10.3390/cancers13040809. Cancers (Basel). 2021. PMID: 33671939 Free PMC article.
Background: Well-annotated, high-quality biorepositories provide a valuable platform to support translational research. However, most biorepositories have poor representation of minority groups, limiting the ability to address health disparities. ...
Background: Well-annotated, high-quality biorepositories provide a valuable platform to support translational research. However, most biorep …
"Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke.
Bliden KP, Raviv G, Tantry US, Chaudhary R, Cochran JW, Navarese EP, Brannan T, Vyas A, Gurbel PA. Bliden KP, et al. J Thromb Thrombolysis. 2019 Feb;47(2):192-199. doi: 10.1007/s11239-019-01813-0. J Thromb Thrombolysis. 2019. PMID: 30673942
Our preliminary data suggest that AIS is associated with faster ex-vivo clot formation, and poor antiplatelet response. Future study of the TEG6s to "blueprint" hemostasis is warranted in the stroke population....
Our preliminary data suggest that AIS is associated with faster ex-vivo clot formation, and poor antiplatelet response. Future study …
Role of histological findings and pathologic diagnosis for detection of human papillomavirus infection in men.
Vyas NS, Pierce Campbell CM, Mathew R, Abrahamsen M, Van der Kooi K, Jukic DM, Stoler MH, Villa LL, da Silva RC, Lazcano-Ponce E, Quiterio M, Salmeron J, Sirak BA, Ingles DJ, Giuliano AR, Messina JL. Vyas NS, et al. J Med Virol. 2015 Oct;87(10):1777-87. doi: 10.1002/jmv.24238. Epub 2015 May 6. J Med Virol. 2015. PMID: 25945468 Free PMC article.
Pairwise concordance for condyloma was fair to good (k = 0.30-0.67) and poor to moderate for penile intraepithelial neoplasia (k = -0.05 to 0.42). ...
Pairwise concordance for condyloma was fair to good (k = 0.30-0.67) and poor to moderate for penile intraepithelial neoplasia (k = -0 …
The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage.
Hendrix P, Foreman PM, Harrigan MR, Fisher WS Rd, Vyas NA, Lipsky RH, Lin M, Walters BC, Tubbs RS, Shoja MM, Pittet JF, Mathru M, Griessenauer CJ. Hendrix P, et al. Nitric Oxide. 2017 Dec 1;71:52-56. doi: 10.1016/j.niox.2017.10.008. Epub 2017 Oct 24. Nitric Oxide. 2017. PMID: 29079038
A lower Glasgow Coma Scale score and a history of ischemic vascular disease were also associated with cardiac instability. Furthermore, cardiac instability independently predicted poor functional outcome upon discharge from the hospital. CONCLUSIONS: The C allele of the eN …
A lower Glasgow Coma Scale score and a history of ischemic vascular disease were also associated with cardiac instability. Furthermore, card …
11 results