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2024 1

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Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2022 Feb 12;399(10325):665-676. doi: 10.1016/S0140-6736(22)00163-5. Lancet. 2022. PMID: 35151397 Free PMC article. Clinical Trial.
BACKGROUND: Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety of casiriv …
BACKGROUND: Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domai …
Monitoring coeliac disease in 2024, time to change practice?
Raju SA, Shiha MG, Penny HA. Raju SA, et al. Curr Opin Gastroenterol. 2024 May 1;40(3):190-195. doi: 10.1097/MOG.0000000000001009. Epub 2024 Mar 13. Curr Opin Gastroenterol. 2024. PMID: 38547329 Review.
Testing for urinary and/or stool gluten immunogenic peptides may help identify recent gluten exposure, but further studies are still warranted to evaluate the accuracy and applicability of this approach. Measuring spikes in circulating Interleukin-2 following gluten challe …
Testing for urinary and/or stool gluten immunogenic peptides may help identify recent gluten exposure, but further studies are still warrant …
A normative approach to neuromotor control.
Berniker M, Penny S. Berniker M, et al. Biol Cybern. 2019 Apr;113(1-2):83-92. doi: 10.1007/s00422-018-0777-7. Epub 2018 Sep 3. Biol Cybern. 2019. PMID: 30178151
Computational explanations of electrophysiological data often rely on firing rate models or deterministic spiking models. Yet neither can accurately describe the interactions of neurons that issue spikes, probabilistically. Here we take a normative approach by desig …
Computational explanations of electrophysiological data often rely on firing rate models or deterministic spiking models. Yet neither …
Bayesian comparison of neurovascular coupling models using EEG-fMRI.
Rosa MJ, Kilner JM, Penny WD. Rosa MJ, et al. PLoS Comput Biol. 2011 Jun;7(6):e1002070. doi: 10.1371/journal.pcbi.1002070. Epub 2011 Jun 16. PLoS Comput Biol. 2011. PMID: 21698175 Free PMC article.
We show that the BOLD signal is dependent upon both the synaptic and spiking activity but that the relative contributions of these two inputs are dependent upon the underlying neuronal firing rate. ...However, when the neuronal firing rate is high then both synaptic and …
We show that the BOLD signal is dependent upon both the synaptic and spiking activity but that the relative contributions of these tw …
A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) for extraction of drug metabolites in liquid chromatography/mass spectrometry data from biological matrices.
Zhu P, Ding W, Tong W, Ghosal A, Alton K, Chowdhury S. Zhu P, et al. Rapid Commun Mass Spectrom. 2009 Jun;23(11):1563-72. doi: 10.1002/rcm.4041. Rapid Commun Mass Spectrom. 2009. PMID: 19408276
The effectiveness of BgS-NoRA was examined in biological matrices by spiking blank plasma extract, bile and urine with diclofenac and ibuprofen that have been pre-metabolized by microsomal incubation. ...
The effectiveness of BgS-NoRA was examined in biological matrices by spiking blank plasma extract, bile and urine with diclofenac and …