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Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2021 May 29;397(10289):2049-2059. doi: 10.1016/S0140-6736(21)00897-7. Epub 2021 May 14. Lancet. 2021. PMID: 34000257 Free PMC article. Clinical Trial.
Eligible and consenting patients were randomly assigned (1:1) to receive either usual care alone (usual care group) or usual care plus high-titre convalescent plasma (convalescent plasma group). The primary outcome was 28-day mortality, analysed on an intention-to-treat ba …
Eligible and consenting patients were randomly assigned (1:1) to receive either usual care alone (usual care group) or usual care plus high- …
mRNA versus inactivated virus COVID-19 vaccines in multiple sclerosis: Humoral responses and protectivity-Does it matter?
Tütüncü M, Demir S, Arslan G, Dinç Ö, Şen S, Gündüz T, Uzunköprü C, Gümüş H, Tütüncü M, Akçin R, Özakbaş S, Köseoğlu M, Bünül SD, Gezen O, Tezer DÇ, Baba C, Özen PA, Koç R, Elverdi T, Uygunoğlu U, Kürtüncü M, Beckmann Y, Doğan İG, Turan ÖF, Boz C, Terzi M, Tuncer A, Saip S, Karabudak R, Kocazeybek B, Efendi H, Bilge U, Siva A. Tütüncü M, et al. Mult Scler Relat Disord. 2023 Jul;75:104761. doi: 10.1016/j.msard.2023.104761. Epub 2023 May 10. Mult Scler Relat Disord. 2023. PMID: 37247488 Free PMC article.
PwMS were sub-grouped according to the mode of action of the DMTs that they were receiving. SARS-CoV-2 IgG titers were evaluated by chemiluminescent microparticle immunoassay. ...B-cell-depleting therapies fingolimod and cladribine were associated with attenuated antibody …
PwMS were sub-grouped according to the mode of action of the DMTs that they were receiving. SARS-CoV-2 IgG titers were evaluated by c …
Radiation-associated thyrotoxicosis.
Katayama S, Shimaoka K, Osman G. Katayama S, et al. J Surg Oncol. 1986 Oct;33(2):84-7. doi: 10.1002/jso.2930330205. J Surg Oncol. 1986. PMID: 2945053
In 11 out of 16 patients who were tested for antithyroglobulin and antimicrosomal showed positive titers of either or both antibodies (69%). In a small number of patients, thyroid stimulating immunoglobulins were studied; long-acting thyroid stimulators (LATS) were positiv …
In 11 out of 16 patients who were tested for antithyroglobulin and antimicrosomal showed positive titers of either or both antibodies …
Asymptomatic versus symptomatic SARS-CoV-2 infection: a cross-sectional seroprevalence study.
El-Ghitany EM, Hashish MH, Farghaly AG, Omran EA, Osman NA, Fekry MM. El-Ghitany EM, et al. Trop Med Health. 2022 Dec 27;50(1):98. doi: 10.1186/s41182-022-00490-9. Trop Med Health. 2022. PMID: 36575501 Free PMC article.
The number of symptoms was positively correlated with anti-S titer and both were positively correlated with adult body mass index. ...
The number of symptoms was positively correlated with anti-S titer and both were positively correlated with adult body mass index. .. …
Antisynthetase Syndrome Post Shingrix and Pneumovax Vaccinations, Possible Correlation.
Osman A, Almusa A, Ryad R, Sumbulyuksel B. Osman A, et al. Cureus. 2022 May 17;14(5):e25085. doi: 10.7759/cureus.25085. eCollection 2022 May. Cureus. 2022. PMID: 35719791 Free PMC article.
Eight days after the onset of his symptoms he was diagnosed with acute interstitial pneumonitis based on CT scan of the chest which later appeared to be consistent with the diagnosis of antisynthetase syndrome in light of findings consistent with mechanic's hands on examination, …
Eight days after the onset of his symptoms he was diagnosed with acute interstitial pneumonitis based on CT scan of the chest which later ap …
Molecular detection of Epstein-Barr virus among Sudanese patients diagnosed with Hashimoto's thyroiditis.
Hamad MN, Mohamed FI, Osman MM, Jadid AA, Abdalrhman IK, Yousif AM, Alabid T, Edris AMM, Mohamed NS, Siddig EE, Ahmed A. Hamad MN, et al. BMC Res Notes. 2023 Oct 19;16(1):283. doi: 10.1186/s13104-023-06399-8. BMC Res Notes. 2023. PMID: 37858193 Free PMC article.
Studies have reported a wide range of frequencies indicating the presence of EBV in HT, and patients with autoimmune thyroiditis have increased titers of anti-EBV antibodies in their sera compared to healthy subjects. ...
Studies have reported a wide range of frequencies indicating the presence of EBV in HT, and patients with autoimmune thyroiditis have increa …
Higher mucosal antibody concentrations in women with genital tract inflammation.
Sobia P, Pillay T, Liebenberg LJP, Sivro A, Mansoor LE, Osman F, Passmore JS, Abdool Karim Q, Abdool Karim SS, Baxter C, McKinnon LR, Archary D. Sobia P, et al. Sci Rep. 2021 Dec 6;11(1):23514. doi: 10.1038/s41598-021-02954-0. Sci Rep. 2021. PMID: 34873252 Free PMC article. Clinical Trial.

Adjusted linear mixed models showed several pro-inflammatory, chemotactic, growth factors, and adaptive cytokines significantly correlated with higher titers of IgM, IgA and IgG subclasses (p < 0.05). The strong and significant positive correlations between mucosal anti

…
Adjusted linear mixed models showed several pro-inflammatory, chemotactic, growth factors, and adaptive cytokines significantly correlated w …
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Collier DA, De Marco A, Ferreira IATM, Meng B, Datir RP, Walls AC, Kemp SA, Bassi J, Pinto D, Silacci-Fregni C, Bianchi S, Tortorici MA, Bowen J, Culap K, Jaconi S, Cameroni E, Snell G, Pizzuto MS, Pellanda AF, Garzoni C, Riva A; CITIID-NIHR BioResource COVID-19 Collaboration; Elmer A, Kingston N, Graves B, McCoy LE, Smith KGC, Bradley JR, Temperton N, Ceron-Gutierrez L, Barcenas-Morales G; COVID-19 Genomics UK (COG-UK) Consortium; Harvey W, Virgin HW, Lanzavecchia A, Piccoli L, Doffinger R, Wills M, Veesler D, Corti D, Gupta RK. Collier DA, et al. Nature. 2021 May;593(7857):136-141. doi: 10.1038/s41586-021-03412-7. Epub 2021 Mar 11. Nature. 2021. PMID: 33706364
The sera from individuals who received the vaccine exhibited a broad range of neutralizing titres against the wild-type pseudoviruses that were modestly reduced against the B.1.1.7 variant. ...
The sera from individuals who received the vaccine exhibited a broad range of neutralizing titres against the wild-type pseudoviruses …
Assessment of the therapeutic potential of a novel phosphoramidate acyclic nucleoside on induced hepatocellular carcinoma in rat model.
Said YA, Hammad SF, Halim MI, El-Moneim AA, Osman A. Said YA, et al. Life Sci. 2024 Apr 25:122669. doi: 10.1016/j.lfs.2024.122669. Online ahead of print. Life Sci. 2024. PMID: 38677390
DEN-injected rats suffered hepatomegaly, oxidative stress, elevated liver enzymes, hypoalbuminemia, bilirubinemia and skyrocketed AFP plasma titre. SH-PAN-19 alleviated the DEN-induced alterations in apoptotic, angiogenic and inflammatory markers. ...
DEN-injected rats suffered hepatomegaly, oxidative stress, elevated liver enzymes, hypoalbuminemia, bilirubinemia and skyrocketed AFP plasma …
In Elimination Settings, Measles Antibodies Wane After Vaccination but Not After Infection: A Systematic Review and Meta-Analysis.
Bolotin S, Osman S, Hughes SL, Ariyarajah A, Tricco AC, Khan S, Li L, Johnson C, Friedman L, Gul N, Jardine R, Faulkner M, Hahné SJM, Heffernan JM, Dabbagh A, Rota PA, Severini A, Jit M, Durrheim DN, Orenstein WA, Moss WJ, Funk S, Turner N, Schluter W, Jawad JS, Crowcroft NS. Bolotin S, et al. J Infect Dis. 2022 Sep 28;226(7):1127-1139. doi: 10.1093/infdis/jiac039. J Infect Dis. 2022. PMID: 35417025
RESULTS: Using linear regression, we found that geometric mean titers (GMTs) decreased significantly in individuals who received 2 doses of measles-containing vaccine (MCV) by 121.8 mIU/mL (95% confidence interval [CI], -212.4 to -31.1) per year since vaccination over 1 to …
RESULTS: Using linear regression, we found that geometric mean titers (GMTs) decreased significantly in individuals who received 2 do …
58 results