Oridonin employs interleukin 1 receptor type 2 to treat noise-induced hearing loss by blocking inner ear inflammation.
Chen MB, Li MH, Wu LY, Wang R, Long X, Zhang L, Sun W, Guo WW, Pan Y, Zhang YS, Lin C, Shi X, Yang SM.
Chen MB, et al.
Biochem Pharmacol. 2023 Apr;210:115457. doi: 10.1016/j.bcp.2023.115457. Epub 2023 Feb 16.
Biochem Pharmacol. 2023.
PMID: 36806583
Recently, the anti-inflammatory traditional medicine oridonin (Ori) has been reported to provide hearing protection in mice after noise exposure by blocking the NLRP3-never in mitosis gene A-related kinase 7 (NEK7)-inflammasome complex assembly. Using RNA sequencing analys …
Recently, the anti-inflammatory traditional medicine oridonin (Ori) has been reported to provide hearing protection in mice after noi …