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The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.
Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M. Schilperoort M, et al. Among authors: okolo a. EMBO Mol Med. 2018 Mar;10(3):e8047. doi: 10.15252/emmm.201708047. EMBO Mol Med. 2018. PMID: 29343498 Free PMC article.
Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice.
Rosell M, Kaforou M, Frontini A, Okolo A, Chan YW, Nikolopoulou E, Millership S, Fenech ME, MacIntyre D, Turner JO, Moore JD, Blackburn E, Gullick WJ, Cinti S, Montana G, Parker MG, Christian M. Rosell M, et al. Among authors: okolo a. Am J Physiol Endocrinol Metab. 2014 Apr 15;306(8):E945-64. doi: 10.1152/ajpendo.00473.2013. Epub 2014 Feb 18. Am J Physiol Endocrinol Metab. 2014. PMID: 24549398 Free PMC article.