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Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study.
Howard JF Jr, Bresch S, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Lowcock R, Vanderkelen M, Leite MI; RAISE Study Team. Howard JF Jr, et al. Lancet Neurol. 2023 May;22(5):395-406. doi: 10.1016/S1474-4422(23)00080-7. Lancet Neurol. 2023. PMID: 37059508 Clinical Trial.
TEAEs occurred in 66 (77%) patients in the zilucoplan group and in 62 (70%) patients in the placebo group. The most common TEAE was injection-site bruising (n=14 [16%] in the zilucoplan group and n=8 [9%] in the placebo group). ...
TEAEs occurred in 66 (77%) patients in the zilucoplan group and in 62 (70%) patients in the placebo group. The most common TEAE was injectio …
Difficulties in laboratory diagnosis of coexistent lupus anticoagulant and factor VIII inhibitors: case report and review of literature.
Belhadj M, Cheikhrouhou M, Guermazi S. Belhadj M, et al. Ann Biol Clin (Paris). 2023 Oct 20;81(4):417-423. doi: 10.1684/abc.2023.1825. Ann Biol Clin (Paris). 2023. PMID: 37791505 Review.
Curiously, the initial physical examination revealed several hematoma and bruises of varying sizes. Biologically, a prolonged activated partial thromboplastin time (APTT) was objectified and was not corrected by the mixing study. ...
Curiously, the initial physical examination revealed several hematoma and bruises of varying sizes. Biologically, a prolonged activat …
Management of blunt renal trauma on pre-existing diseased kidneys: a cross-sectional study.
Saadi A, Maatougui J, Hermi A, Mokadem S, Boussaffa H, Zaghbib S, Bellali M, Allouche M, Jrad M, Ayed H, Bouzouita A, Derouiche A, Chakroun M, Ben Slama MR. Saadi A, et al. Ann Med Surg (Lond). 2023 Apr 10;85(6):2432-2436. doi: 10.1097/MS9.0000000000000594. eCollection 2023 Jun. Ann Med Surg (Lond). 2023. PMID: 37363469 Free PMC article.
CONCLUSION: Kidneys with underlying pathology are habitually more susceptible to trauma. Contusions are often benign contrasting with a high nephrectomy rate....
CONCLUSION: Kidneys with underlying pathology are habitually more susceptible to trauma. Contusions are often benign contrasting with …