TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence.
Farfariello V, Gordienko DV, Mesilmany L, Touil Y, Germain E, Fliniaux I, Desruelles E, Gkika D, Roudbaraki M, Shapovalov G, Noyer L, Lebas M, Allart L, Zienthal-Gelus N, Iamshanova O, Bonardi F, Figeac M, Laine W, Kluza J, Marchetti P, Quesnel B, Metzger D, Bernard D, Parys JB, Lemonnier L, Prevarskaya N.
Farfariello V, et al.
Nat Commun. 2022 Feb 17;13(1):956. doi: 10.1038/s41467-022-28597-x.
Nat Commun. 2022.
PMID: 35177596
Free PMC article.
Cellular senescence is implicated in a great number of diseases including cancer. Although alterations in mitochondrial metabolism were reported as senescence drivers, the underlying mechanisms remain elusive. ...
Cellular senescence is implicated in a great number of diseases including cancer. Although alterations in mitochondrial metabolism we …