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2002 2
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Page 1
Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.
Hart RG, Sharma M, Mundl H, Kasner SE, Bangdiwala SI, Berkowitz SD, Swaminathan B, Lavados P, Wang Y, Wang Y, Davalos A, Shamalov N, Mikulik R, Cunha L, Lindgren A, Arauz A, Lang W, Czlonkowska A, Eckstein J, Gagliardi RJ, Amarenco P, Ameriso SF, Tatlisumak T, Veltkamp R, Hankey GJ, Toni D, Bereczki D, Uchiyama S, Ntaios G, Yoon BW, Brouns R, Endres M, Muir KW, Bornstein N, Ozturk S, O'Donnell MJ, De Vries Basson MM, Pare G, Pater C, Kirsch B, Sheridan P, Peters G, Weitz JI, Peacock WF, Shoamanesh A, Benavente OR, Joyner C, Themeles E, Connolly SJ; NAVIGATE ESUS Investigators. Hart RG, et al. N Engl J Med. 2018 Jun 7;378(23):2191-2201. doi: 10.1056/NEJMoa1802686. Epub 2018 May 16. N Engl J Med. 2018. PMID: 29766772 Free article. Clinical Trial.
The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K (gK) Is Required for gB Binding to Akt, Release of Intracellular Calcium, and Fusion of the Viral Envelope with Plasma Membranes.
Musarrat F, Jambunathan N, Rider PJF, Chouljenko VN, Kousoulas KG. Musarrat F, et al. J Virol. 2018 Feb 26;92(6):e01842-17. doi: 10.1128/JVI.01842-17. Print 2018 Mar 15. J Virol. 2018. PMID: 29321326 Free PMC article.
Previously, we have shown that the amino terminus of glycoprotein K (gK) binds to the amino terminus of gB and that deletion of the amino-terminal 38 amino acids of gK prevents herpes simplex virus 1 (HSV-1) infection of mouse trigeminal ganglia after …
Previously, we have shown that the amino terminus of glycoprotein K (gK) binds to the amino terminus of gB and that deletion o …
Two Sides to Every Story: Herpes Simplex Type-1 Viral Glycoproteins gB, gD, gH/gL, gK, and Cellular Receptors Function as Key Players in Membrane Fusion.
Jambunathan N, Clark CM, Musarrat F, Chouljenko VN, Rudd J, Kousoulas KG. Jambunathan N, et al. Viruses. 2021 Sep 16;13(9):1849. doi: 10.3390/v13091849. Viruses. 2021. PMID: 34578430 Free PMC article. Review.
This hypothesis was substantiated by the observation that a small deletion in the amino terminus of gK prevents entry into neuronal axons while allowing entry into other cells via endocytosis. ...
This hypothesis was substantiated by the observation that a small deletion in the amino terminus of gK prevents entry into neuronal a …
Predicted Structure and Functions of the Prototypic Alphaherpesvirus Herpes Simplex Virus Type-1 UL37 Tegument Protein.
Collantes TMA, Clark CM, Musarrat F, Jambunathan N, Jois S, Kousoulas KG. Collantes TMA, et al. Viruses. 2022 Oct 4;14(10):2189. doi: 10.3390/v14102189. Viruses. 2022. PMID: 36298744 Free PMC article.
Mutagenesis analysis delineated the UL37 domains necessary for retrograde transport and viral replication. Specifically, the amino-terminal 480 amino acids are dispensable for virus replication in epithelial cell culture, but it is unknown whether this amino- …
Mutagenesis analysis delineated the UL37 domains necessary for retrograde transport and viral replication. Specifically, the amino-te …
Synthesis, characterization of alpha-amino acid Schiff base derived Ru/Pt complexes: Induces cytotoxicity in HepG2 cell via protein binding and ROS generation.
Alsalme A, Laeeq S, Dwivedi S, Khan MS, Al Farhan K, Musarrat J, Khan RA. Alsalme A, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jun 15;163:1-7. doi: 10.1016/j.saa.2016.03.012. Epub 2016 Mar 14. Spectrochim Acta A Mol Biomol Spectrosc. 2016. PMID: 27002605
We have synthesized two new complexes of platinum (1) and ruthenium (2) with alpha-amino acid, l-alanine, and 2,3-dihydroxybenzaldehyde derived Schiff base (L). ...
We have synthesized two new complexes of platinum (1) and ruthenium (2) with alpha-amino acid, l-alanine, and 2,3-dihydroxybenzaldehy …
Glycation reduces the binding dynamics of aflatoxin B1 to human serum albumin: a comprehensive spectroscopic and computational investigation.
Qureshi MA, Amir M, Khan RH, Musarrat J, Javed S. Qureshi MA, et al. J Biomol Struct Dyn. 2023;41(24):14797-14811. doi: 10.1080/07391102.2023.2194000. Epub 2023 Apr 5. J Biomol Struct Dyn. 2023. PMID: 37021366
The circular dichroism study confirms the change in the secondary structure of nHSA and gHSA in the presence of AFB(1), followed by alterations in the melting temperature (T(m)) of nHSA and gHSA. In silico computational findings envisaged the amino acid residues and bonds …
The circular dichroism study confirms the change in the secondary structure of nHSA and gHSA in the presence of AFB(1), followed by alterati …
The chloroplast genome of Farsetia hamiltonii Royle, phylogenetic analysis, and comparative study with other members of Clade C of Brassicaceae.
Javaid N, Ramzan M, Khan IA, Alahmadi TA, Datta R, Fahad S, Danish S. Javaid N, et al. BMC Plant Biol. 2022 Aug 2;22(1):384. doi: 10.1186/s12870-022-03750-2. BMC Plant Biol. 2022. PMID: 35918648 Free PMC article.
The genomes of F. hamiltonii and F. occidentalis show shared amino acid frequencies and codon use, RNA editing sites, simple sequence repeats, and oligonucleotide repeats. ...
The genomes of F. hamiltonii and F. occidentalis show shared amino acid frequencies and codon use, RNA editing sites, simple sequence …
The anti-HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV-2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID-19 infections.
Musarrat F, Chouljenko V, Dahal A, Nabi R, Chouljenko T, Jois SD, Kousoulas KG. Musarrat F, et al. J Med Virol. 2020 Oct;92(10):2087-2095. doi: 10.1002/jmv.25985. Epub 2020 May 17. J Med Virol. 2020. PMID: 32374457 Free PMC article.
In-silico docking experiments suggested the possibility that nelfinavir may bind inside the S trimer structure, proximal to the S2 amino terminus directly inhibiting S-n- and S-o-mediated membrane fusion. ...
In-silico docking experiments suggested the possibility that nelfinavir may bind inside the S trimer structure, proximal to the S2 amino …
Titanium dioxide nanoparticles preferentially bind in subdomains IB, IIA of HSA and minor groove of DNA.
Ali K, Abul Qais F, Dwivedi S, Abdel-Salam EM, Ansari SM, Saquib Q, Faisal M, Al-Khedhairy AA, Al-Shaeri M, Musarrat J. Ali K, et al. J Biomol Struct Dyn. 2018 Aug;36(10):2530-2542. doi: 10.1080/07391102.2017.1361339. Epub 2017 Aug 10. J Biomol Struct Dyn. 2018. PMID: 28753123
The docking analysis of TiO(2)-NPs with HSA revealed its preferential binding with aromatic and non-aromatic amino acids in subdomain IIA and IB hydrophobic cavity of HSA. Also, the TiO(2)-NPs docking revealed the selective binding with A-T bases in minor groove of DNA....
The docking analysis of TiO(2)-NPs with HSA revealed its preferential binding with aromatic and non-aromatic amino acids in subdomain …
Tetracycline-Cu(II) photo-induced fragmentation of serum albumin.
Khan MA, Musarrat J. Khan MA, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Apr;131(4):439-46. doi: 10.1016/s1532-0456(02)00033-9. Comp Biochem Physiol C Toxicol Pharmacol. 2002. PMID: 11976059
Photoexcited tetracycline in combination with 100 microM Cu(II) enhanced the protein fragmentation process with concurrent increase in free radical production. The significant release of acid-soluble amino groups and carbonyl groups from treated albumin provided quantitati …
Photoexcited tetracycline in combination with 100 microM Cu(II) enhanced the protein fragmentation process with concurrent increase in free …
14 results