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Year Number of Results
1984 2
1985 1
1987 1
1989 2
1990 2
1991 1
1992 1
1993 1
1994 1
1996 6
1997 5
1998 2
1999 6
2000 3
2001 1
2002 6
2004 3
2005 4
2008 1
2009 2
2010 2
2012 1
2014 1
2018 1
2020 2
2021 1
2022 1
2023 2
2024 1

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61 results

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Page 1
Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing.
Jiang Y, Trotsyuk AA, Niu S, Henn D, Chen K, Shih CC, Larson MR, Mermin-Bunnell AM, Mittal S, Lai JC, Saberi A, Beard E, Jing S, Zhong D, Steele SR, Sun K, Jain T, Zhao E, Neimeth CR, Viana WG, Tang J, Sivaraj D, Padmanabhan J, Rodrigues M, Perrault DP, Chattopadhyay A, Maan ZN, Leeolou MC, Bonham CA, Kwon SH, Kussie HC, Fischer KS, Gurusankar G, Liang K, Zhang K, Nag R, Snyder MP, Januszyk M, Gurtner GC, Bao Z. Jiang Y, et al. Nat Biotechnol. 2023 May;41(5):652-662. doi: 10.1038/s41587-022-01528-3. Epub 2022 Nov 24. Nat Biotechnol. 2023. PMID: 36424488
Here we overcome these issues by developing a flexible bioelectronic system consisting of wirelessly powered, closed-loop sensing and stimulation circuits with skin-interfacing hydrogel electrodes capable of on-demand adhesion and detachment. In mice, we demonstrate that o …
Here we overcome these issues by developing a flexible bioelectronic system consisting of wirelessly powered, closed-loop sensing and stimul …
Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing.
Henn D, Zhao D, Sivaraj D, Trotsyuk A, Bonham CA, Fischer KS, Kehl T, Fehlmann T, Greco AH, Kussie HC, Moortgat Illouz SE, Padmanabhan J, Barrera JA, Kneser U, Lenhof HP, Januszyk M, Levi B, Keller A, Longaker MT, Chen K, Qi LS, Gurtner GC. Henn D, et al. Nat Commun. 2023 Aug 7;14(1):4729. doi: 10.1038/s41467-023-40519-z. Nat Commun. 2023. PMID: 37550295 Free PMC article.
Cell-based therapies, while having shown benefits for the treatment of chronic wounds, have not yet achieved widespread adoption into clinical practice. We developed a CRISPR/Cas9 approach to precisely edit murine dendritic cells to enhance their therapeutic potential for …
Cell-based therapies, while having shown benefits for the treatment of chronic wounds, have not yet achieved widespread adoption into clinic …
Postexercise hypotension: central mechanisms.
Chen CY, Bonham AC. Chen CY, et al. Exerc Sport Sci Rev. 2010 Jul;38(3):122-7. doi: 10.1097/JES.0b013e3181e372b5. Exerc Sport Sci Rev. 2010. PMID: 20577060 Free PMC article. Review.
Iron Chelation with Transdermal Deferoxamine Accelerates Healing of Murine Sickle Cell Ulcers.
Rodrigues M, Bonham CA, Minniti CP, Gupta K, Longaker MT, Gurtner GC. Rodrigues M, et al. Adv Wound Care (New Rochelle). 2018 Oct 1;7(10):323-332. doi: 10.1089/wound.2018.0789. Epub 2018 Oct 11. Adv Wound Care (New Rochelle). 2018. PMID: 30374417 Free PMC article.
In this study, we tested the ability of DFO delivered via a transdermal delivery system (DFO-TDDS) to accelerate healing in a murine model of SCU. Approach: Excisional wounds were created in a transgenic murine model of SCD expressing >99% human sickle hemoglobin …
In this study, we tested the ability of DFO delivered via a transdermal delivery system (DFO-TDDS) to accelerate healing in a murine …
An internal deletion enhances the transcriptional activity of a recombinant retrovirus in hematopoietic cells in vivo.
MacKenzie KL, Bonham L, Symonds G. MacKenzie KL, et al. J Virol. 1994 Nov;68(11):6924-32. doi: 10.1128/JVI.68.11.6924-6932.1994. J Virol. 1994. PMID: 7933073 Free PMC article.
Lv-myc is a recombinant retrovirus that spontaneously arose during experiments designed to express the provirus LNAv-myc in the hematopoietic system of bone marrow-reconstituted mice (L. Bonham, K. MacKenzie, S. Wood, P. B. Rowe, and G. Symonds, Oncogene 7:22 …
Lv-myc is a recombinant retrovirus that spontaneously arose during experiments designed to express the provirus LNAv-myc in the hematopoieti …
Murine polyubiquitin mRNA sequence.
Finch JS, Bonham K, Krieg P, Bowden GT. Finch JS, et al. Nucleic Acids Res. 1990 Apr 11;18(7):1907. doi: 10.1093/nar/18.7.1907. Nucleic Acids Res. 1990. PMID: 2159627 Free PMC article. No abstract available.
Adipose-Derived Stromal Cells Seeded in Pullulan-Collagen Hydrogels Improve Healing in Murine Burns.
Barrera JA, Trotsyuk AA, Maan ZN, Bonham CA, Larson MR, Mittermiller PA, Henn D, Chen K, Mays CJ, Mittal S, Mermin-Bunnell AM, Sivaraj D, Jing S, Rodrigues M, Kwon SH, Noishiki C, Padmanabhan J, Jiang Y, Niu S, Inayathullah M, Rajadas J, Januszyk M, Gurtner GC. Barrera JA, et al. Tissue Eng Part A. 2021 Jun;27(11-12):844-856. doi: 10.1089/ten.TEA.2020.0320. Epub 2021 May 27. Tissue Eng Part A. 2021. PMID: 33789446
In this study, we examined whether adipose-derived stem cell (ASC)-seeded hydrogels could improve wound healing following thermal injury using a murine contact burn model. Partial thickness contact burns were created on the dorsum of mice. ...We have developed a pul …
In this study, we examined whether adipose-derived stem cell (ASC)-seeded hydrogels could improve wound healing following thermal injury usi …
A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.
Davis EJ, Broestl L, Abdulai-Saiku S, Worden K, Bonham LW, Miñones-Moyano E, Moreno AJ, Wang D, Chang K, Williams G, Garay BI, Lobach I, Devidze N, Kim D, Anderson-Bergman C, Yu GQ, White CC, Harris JA, Miller BL, Bennett DA, Arnold AP, De Jager PL, Palop JJ, Panning B, Yokoyama JS, Mucke L, Dubal DB. Davis EJ, et al. Sci Transl Med. 2020 Aug 26;12(558):eaaz5677. doi: 10.1126/scitranslmed.aaz5677. Sci Transl Med. 2020. PMID: 32848093 Free PMC article.
XY-hAPP mice genetically modified to develop testicles or ovaries showed worse mortality and deficits than did XX-hAPP mice with either gonad, indicating a sex chromosome effect. To dissect whether the absence of a second X chromosome or the presence of a Y chromoso …
XY-hAPP mice genetically modified to develop testicles or ovaries showed worse mortality and deficits than did XX-hAPP mice wi …
Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases.
Cochran JN, Geier EG, Bonham LW, Newberry JS, Amaral MD, Thompson ML, Lasseigne BN, Karydas AM, Roberson ED, Cooper GM, Rabinovici GD, Miller BL, Myers RM, Yokoyama JS; Alzheimer’s Disease Neuroimaging Initiative. Cochran JN, et al. Am J Hum Genet. 2020 May 7;106(5):632-645. doi: 10.1016/j.ajhg.2020.03.010. Epub 2020 Apr 23. Am J Hum Genet. 2020. PMID: 32330418 Free PMC article.
Rare variants in TET2 were enriched in the discovery combined EOAD and FTD cohort (p = 4.6 10(-8), genome-wide corrected p = 0.0026). Most of these variants were canonical LoF or non-coding in predicted regulatory regions. This enrichment replicated across several c …
Rare variants in TET2 were enriched in the discovery combined EOAD and FTD cohort (p = 4.6 10(-8), genome-wide corrected p = 0 …
The translational landscape of mTOR signalling steers cancer initiation and metastasis.
Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. Hsieh AC, et al. Nature. 2012 Feb 22;485(7396):55-61. doi: 10.1038/nature10912. Nature. 2012. PMID: 22367541 Free PMC article.
61 results