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Year Number of Results
1965 1
1969 1
1986 3
1987 2
1988 2
1989 1
1990 3
1991 4
1992 3
1993 4
1994 7
1995 11
1996 6
1997 9
1998 9
1999 10
2000 14
2001 21
2002 12
2003 19
2004 25
2005 17
2006 27
2007 33
2008 40
2009 35
2010 48
2011 73
2012 68
2013 75
2014 102
2015 111
2016 105
2017 125
2018 112
2019 162
2020 170
2021 174
2022 203
2023 194
2024 58

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1,875 results

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Page 1
Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems.
Yang LZ, Wang Y, Li SQ, Yao RW, Luan PF, Wu H, Carmichael GG, Chen LL. Yang LZ, et al. Mol Cell. 2019 Dec 19;76(6):981-997.e7. doi: 10.1016/j.molcel.2019.10.024. Epub 2019 Nov 19. Mol Cell. 2019. PMID: 31757757 Free article.
Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice.
Sun H, Chen N, Yang X, Xia Y, Wu D. Sun H, et al. Ecotoxicol Environ Saf. 2021 Sep 1;220:112340. doi: 10.1016/j.ecoenv.2021.112340. Epub 2021 May 18. Ecotoxicol Environ Saf. 2021. PMID: 34015635 Free article.
Female mice were orally exposed to 0, 0.002 and 0.2 mug/g/d polyethylene microplastics (PE MPs) for 30 days. Colon mucin density was quantized after AB-PAS staining. Mucin 2 (MUC2), inflammatory factors (IL-1beta, IL-6, IL-8 and IL-10), short-chain fatty acid recept …
Female mice were orally exposed to 0, 0.002 and 0.2 mug/g/d polyethylene microplastics (PE MPs) for 30 days. Colon mucin density was …
Muc2 mucin O-glycosylation interacts with enteropathogenic Escherichia coli to influence the development of ulcerative colitis based on the NF-kB signaling pathway.
Wei J, Chen C, Feng J, Zhou S, Feng X, Yang Z, Lu H, Tao H, Li L, Xv H, Xuan J, Wang F. Wei J, et al. J Transl Med. 2023 Nov 8;21(1):793. doi: 10.1186/s12967-023-04687-2. J Transl Med. 2023. PMID: 37940996 Free PMC article.
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine characterized by a compromised intestinal epithelial barrier. Mucin glycans are crucial in preserving barrier function during bacterial infections, although the underlying mechanisms rem …
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine characterized by a compromised intestinal epithelial …
Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway.
Wang B, Zhang J, Liu X, Chai Q, Lu X, Yao X, Yang Z, Sun L, Johnson SF, Schwartz RC, Zheng YH. Wang B, et al. Autophagy. 2022 Oct;18(10):2350-2367. doi: 10.1080/15548627.2022.2031381. Epub 2022 Feb 7. Autophagy. 2022. PMID: 35130104 Free PMC article.
We suggest that ebolaviruses hijack the host protein folding and ERAD machinery to increase their fitness via reticulophagy during infection.Abbreviations: 3-MA: 3-methyladenine; 4-PBA: 4-phenylbutyrate; ACTB: beta-actin; ATF: activating transcription factor; ATG: autophagy-relat …
We suggest that ebolaviruses hijack the host protein folding and ERAD machinery to increase their fitness via reticulophagy during infection …
Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response.
Gao X, Cao Q, Cheng Y, Zhao D, Wang Z, Yang H, Wu Q, You L, Wang Y, Lin Y, Li X, Wang Y, Bian JS, Sun D, Kong L, Birnbaumer L, Yang Y. Gao X, et al. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2960-E2969. doi: 10.1073/pnas.1720696115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531080 Free PMC article.
Furthermore, results showed stress-induced deficient expression of mucin-2 and lysozyme, which may contribute to the disorder of gut microbiota. ...
Furthermore, results showed stress-induced deficient expression of mucin-2 and lysozyme, which may contribute to the disorder of gut …
Advances in MUC1-Mediated Breast Cancer Immunotherapy.
Li Z, Yang D, Guo T, Lin M. Li Z, et al. Biomolecules. 2022 Jul 6;12(7):952. doi: 10.3390/biom12070952. Biomolecules. 2022. PMID: 35883508 Free PMC article. Review.
Since the overexpression and aberrant glycosylation of MUC1 (human mucin) are closely associated with BRCA, it has become an ideal target for BRCA immunotherapies. ...
Since the overexpression and aberrant glycosylation of MUC1 (human mucin) are closely associated with BRCA, it has become an ideal ta …
Role of the mucin-like glycoprotein FCGBP in mucosal immunity and cancer.
Liu Q, Niu X, Li Y, Zhang JR, Zhu SJ, Yang QY, Zhang W, Gong L. Liu Q, et al. Front Immunol. 2022 Jul 22;13:863317. doi: 10.3389/fimmu.2022.863317. eCollection 2022. Front Immunol. 2022. PMID: 35936008 Free PMC article. Review.
IgGFc-binding protein (FCGBP) is a mucin first detected in the intestinal epithelium. It plays an important role in innate mucosal epithelial defense, tumor metastasis, and tumor immunity. FCGBP forms disulfide-linked heterodimers with mucin-2 and members of the tre …
IgGFc-binding protein (FCGBP) is a mucin first detected in the intestinal epithelium. It plays an important role in innate mucosal ep …
Mucin 4 Confers Gemcitabine Resistance and an Unfavorable Prognosis in Patients with Cholangiocarcinoma via AKT Activation.
Pan YR, Wu CE, Jung SM, Huang SC, Lin SH, Chou WC, Chang YC, Chen MH, Hung TH, Yu AL, Huang WK, Yeh CN. Pan YR, et al. Int J Biol Sci. 2023 May 21;19(9):2772-2786. doi: 10.7150/ijbs.79126. eCollection 2023. Int J Biol Sci. 2023. PMID: 37324940 Free PMC article.
Therefore, investigating treatments to overcome GEM resistance in advanced CCA is crucial. Among mucin (MUC) family members, MUC4 showed the greatest increase in the resistant versus parental sublines. ...
Therefore, investigating treatments to overcome GEM resistance in advanced CCA is crucial. Among mucin (MUC) family members, MUC4 sho …
The Role of Adhesion in Helicobacter pylori Persistent Colonization.
Yang H, Wang L, Zhang M, Hu B. Yang H, et al. Curr Microbiol. 2023 Apr 18;80(5):185. doi: 10.1007/s00284-023-03264-6. Curr Microbiol. 2023. PMID: 37071212 Review.
Outer membrane proteins, such as the blood group antigen binding adhesin (BabA) and the sialic acid binding adhesin (SabA), play pivotal roles in binding to human mucins and cellular surfaces. And this may offer different perspectives on eradication....
Outer membrane proteins, such as the blood group antigen binding adhesin (BabA) and the sialic acid binding adhesin (SabA), play pivotal rol …
Mechanism of azithromycin in airway diseases.
Yang J. Yang J. J Int Med Res. 2020 Jun;48(6):300060520932104. doi: 10.1177/0300060520932104. J Int Med Res. 2020. PMID: 32589092 Free PMC article. Review.
Airway mucus hypersecretion is an important component of chronic respiratory diseases. Mucin 5AC (MUC5AC) is the major mucin produced by airway epithelial cells, and hypersecretion of MUC5AC is a sign of various pulmonary inflammatory diseases. ...
Airway mucus hypersecretion is an important component of chronic respiratory diseases. Mucin 5AC (MUC5AC) is the major mucin p …
1,875 results