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Page 1
Establishing the Safe Space via Physiologically Based Biopharmaceutics Modeling. Case Study: Fevipiprant/QAW039.
AAPS J. 2023 Feb 14;25(1):25. doi: 10.1208/s12248-023-00787-5.
AAPS J. 2023.
PMID: 36788163
Multiscale modelling approaches for assessing cosmetic ingredients safety.
Bois FY, Ochoa JGD, Gajewska M, Kovarich S, Mauch K, Paini A, Péry A, Benito JVS, Teng S, Worth A.
Bois FY, et al. Among authors: gajewska m.
Toxicology. 2017 Dec 1;392:130-139. doi: 10.1016/j.tox.2016.05.026. Epub 2016 Jun 4.
Toxicology. 2017.
PMID: 27267299
Free article.
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Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.
Thoma G, Markert C, Lueoend R, Miltz W, Spanka C, Bollbuck B, Wolf RM, Srinivas H, Penno CA, Kiffe M, Gajewska M, Bednarczyk D, Wieczorek G, Evans A, Beerli C, Röhn TA.
Thoma G, et al. Among authors: gajewska m.
J Med Chem. 2023 Dec 14;66(23):16410-16425. doi: 10.1021/acs.jmedchem.3c01866. Epub 2023 Nov 28.
J Med Chem. 2023.
PMID: 38015154
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Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.
Thoma G, Miltz W, Srinivas H, Penno CA, Kiffe M, Gajewska M, Klein K, Evans A, Beerli C, Röhn TA.
Thoma G, et al. Among authors: gajewska m.
J Med Chem. 2024 Mar 28;67(6):5093-5108. doi: 10.1021/acs.jmedchem.4c00290. Epub 2024 Mar 12.
J Med Chem. 2024.
PMID: 38476002
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Physiologically Based Pharmacokinetic Modeling of Oral Absorption, pH, and Food Effect in Healthy Volunteers to Drive Alpelisib Formulation Selection.
Gajewska M, Blumenstein L, Kourentas A, Mueller-Zsigmondy M, Lorenzo S, Sinn A, Velinova M, Heimbach T.
Gajewska M, et al.
AAPS J. 2020 Oct 18;22(6):134. doi: 10.1208/s12248-020-00511-7.
AAPS J. 2020.
PMID: 33070288
Clinical Trial.
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The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data - A case study with caffeine.
Bessems JGM, Paini A, Gajewska M, Worth A.
Bessems JGM, et al. Among authors: gajewska m.
Toxicology. 2017 Dec 1;392:119-129. doi: 10.1016/j.tox.2017.03.012. Epub 2017 Mar 10.
Toxicology. 2017.
PMID: 28288858
Free PMC article.
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Physicochemical screening of antimicrobial agents as potential preservatives for submicron emulsions.
Sznitowska M, Janicki S, Dabrowska EA, Gajewska M.
Sznitowska M, et al. Among authors: gajewska m.
Eur J Pharm Sci. 2002 Jun;15(5):489-95. doi: 10.1016/s0928-0987(02)00034-9.
Eur J Pharm Sci. 2002.
PMID: 12036725
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