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The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
West M, Mhatre M, Ceballos A, Floyd RA, Grammas P, Gabbita SP, Hamdheydari L, Mai T, Mou S, Pye QN, Stewart C, West S, Williamson KS, Zemlan F, Hensley K. West M, et al. Among authors: mhatre m. J Neurochem. 2004 Oct;91(1):133-43. doi: 10.1111/j.1471-4159.2004.02700.x. J Neurochem. 2004. PMID: 15379894 Free article.
Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis.
Hensley K, Fedynyshyn J, Ferrell S, Floyd RA, Gordon B, Grammas P, Hamdheydari L, Mhatre M, Mou S, Pye QN, Stewart C, West M, West S, Williamson KS. Hensley K, et al. Among authors: mhatre m. Neurobiol Dis. 2003 Oct;14(1):74-80. doi: 10.1016/s0969-9961(03)00087-1. Neurobiol Dis. 2003. PMID: 13678668
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