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A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules.
Funk C, Schmeiser V, Ortiz J, Lechner J. Funk C, et al. J Cell Biol. 2014 May 26;205(4):555-71. doi: 10.1083/jcb.201310018. J Cell Biol. 2014. PMID: 24862575 Free PMC article.
Stu1 is also recruited to spindle MTs by different mechanisms depending on the mitotic phase: in metaphase, Stu1 binds directly to the MT lattice, whereas in anaphase, it is localized indirectly to the spindle midzone. In both phases, the activity of TOGL2 is essential for …
Stu1 is also recruited to spindle MTs by different mechanisms depending on the mitotic phase: in metaphase, Stu1 binds directly to the MT la …
Assembly of bipolar microtubule structures by passive cross-linkers and molecular motors.
Johann D, Goswami D, Kruse K. Johann D, et al. Phys Rev E. 2016 Jun;93(6):062415. doi: 10.1103/PhysRevE.93.062415. Epub 2016 Jun 24. Phys Rev E. 2016. PMID: 27415306
During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar filaments called microtubules. The spindle contains the midzone, a stable region of overlapping antiparallel microtubules, that is essent …
During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar fila …