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1978 1
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2009 1
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Page 1
Melanin's Journey from Melanocytes to Keratinocytes: Uncovering the Molecular Mechanisms of Melanin Transfer and Processing.
Bento-Lopes L, Cabaço LC, Charneca J, Neto MV, Seabra MC, Barral DC. Bento-Lopes L, et al. Int J Mol Sci. 2023 Jul 10;24(14):11289. doi: 10.3390/ijms241411289. Int J Mol Sci. 2023. PMID: 37511054 Free PMC article. Review.
While the molecular mechanisms of melanin synthesis and transport in melanocytes are now well characterized, much less is known about melanin transfer and processing within keratinocytes. ...Moreover, we discuss recent evidence that sheds light on the regulation of …
While the molecular mechanisms of melanin synthesis and transport in melanocytes are now well characterized, much less is known about …
Artificial Allomelanin Nanoparticles.
Zhou X, McCallum NC, Hu Z, Cao W, Gnanasekaran K, Feng Y, Stoddart JF, Wang Z, Gianneschi NC. Zhou X, et al. ACS Nano. 2019 Oct 22;13(10):10980-10990. doi: 10.1021/acsnano.9b02160. Epub 2019 Sep 16. ACS Nano. 2019. PMID: 31524373
Allomelanin is a type of nitrogen-free melanin most commonly found in fungi. Its existence enhances resistance of the organisms to environmental damage and helps fungi survive harsh radiation conditions such as those found on spacecraft and inside contaminated nuclear powe …
Allomelanin is a type of nitrogen-free melanin most commonly found in fungi. Its existence enhances resistance of the organisms to en …
Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis.
Kobayashi N, Nakagawa A, Muramatsu T, Yamashina Y, Shirai T, Hashimoto MW, Ishigaki Y, Ohnishi T, Mori T. Kobayashi N, et al. J Invest Dermatol. 1998 May;110(5):806-10. doi: 10.1046/j.1523-1747.1998.00178.x. J Invest Dermatol. 1998. PMID: 9579550 Free article.
Melanin can form supranuclear caps in human epidermis, suggesting that intracellular melanin reduces ultraviolet transmission to underlying cell nuclei and inhibits the formation of ultraviolet induced DNA photoproducts. ...We found that epidermal cells with …
Melanin can form supranuclear caps in human epidermis, suggesting that intracellular melanin reduces ultraviolet transm …
Melanin Distribution in Human Skin: Influence of Cytoskeletal, Polarity, and Centrosome-Related Machinery of Stratum basale Keratinocytes.
Castellano-Pellicena I, Morrison CG, Bell M, O'Connor C, Tobin DJ. Castellano-Pellicena I, et al. Int J Mol Sci. 2021 Mar 19;22(6):3143. doi: 10.3390/ijms22063143. Int J Mol Sci. 2021. PMID: 33808676 Free PMC article.
Cytochalasin-B treatment disassembled supra-nuclear melanin caps, while nocodazole treatment moved melanin from the apical to basal KC domain. ...This mechanism may control melanin's strategic position within UVR-exposed KCs....
Cytochalasin-B treatment disassembled supra-nuclear melanin caps, while nocodazole treatment moved melanin from the api …
The story of melanocyte: a long way from bench to bedside.
Shahbazi A, Zargar SJ, Aghdami N, Habibi M. Shahbazi A, et al. Cell Tissue Bank. 2024 Mar;25(1):143-157. doi: 10.1007/s10561-023-10081-5. Epub 2023 Apr 12. Cell Tissue Bank. 2024. PMID: 37046149 Review.
The color of skin is influenced by a number of pigments, including melanin, which is produced by cells called melanocytes. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal. ...This review, thus, summarizes the current understanding of …
The color of skin is influenced by a number of pigments, including melanin, which is produced by cells called melanocytes. Most skin …
Rab GTPases: Key players in melanosome biogenesis, transport, and transfer.
Fukuda M. Fukuda M. Pigment Cell Melanoma Res. 2021 Mar;34(2):222-235. doi: 10.1111/pcmr.12931. Epub 2020 Oct 14. Pigment Cell Melanoma Res. 2021. PMID: 32997883 Review.
Melanosomes are specialized intracellular organelles that produce and store melanin pigments in melanocytes, which are present in several mammalian tissues and organs, including the skin, hair, and eyes. ...They are subsequently transferred to neighboring keratinocytes by …
Melanosomes are specialized intracellular organelles that produce and store melanin pigments in melanocytes, which are present in sev …
Isolation and identification of pigments from oyster mushrooms with black, yellow and pink caps.
Zhang Y, Wu X, Huang C, Zhang Z, Gao W. Zhang Y, et al. Food Chem. 2022 Mar 15;372:131171. doi: 10.1016/j.foodchem.2021.131171. Epub 2021 Sep 20. Food Chem. 2022. PMID: 34601416
Nevertheless, HPLC and elemental analysis indicated that the melanin in oyster mushrooms was actually a mixture of eumelanin and phaeomelanin. Differences in the quantities and relative proportions of eumelanin and phaeomelanin resulted in the color variation in oyster mus …
Nevertheless, HPLC and elemental analysis indicated that the melanin in oyster mushrooms was actually a mixture of eumelanin and phae …
Synthesis and structural characteristics analysis of melanin pigments induced by blue light in Morchella sextelata.
Qiu Z, Wang S, Zhao J, Cui L, Wang X, Cai N, Li H, Ren S, Li T, Shu L. Qiu Z, et al. Front Microbiol. 2023 Sep 29;14:1276457. doi: 10.3389/fmicb.2023.1276457. eCollection 2023. Front Microbiol. 2023. PMID: 37840742 Free PMC article.
Transmission and scanning electron microscopy revealed the localization of melanin within the mycelium and its ultrastructural characteristics. ...The structural characteristics of melanin were analyzed using FTIR, NMR, HPLC, and elemental analysis, which confirmed …
Transmission and scanning electron microscopy revealed the localization of melanin within the mycelium and its ultrastructural charac …
Non-invasive visualization of melanin and melanocytes by reflectance-mode confocal microscopy.
Yamashita T, Kuwahara T, González S, Takahashi M. Yamashita T, et al. J Invest Dermatol. 2005 Jan;124(1):235-40. doi: 10.1111/j.0022-202X.2004.23562.x. J Invest Dermatol. 2005. PMID: 15654979 Free article.
In contrast, in the human skin, typical dendritic melanocytes were hardly observed even in pigmented lesions, although supranuclear melanin caps were easily visible. These results suggested that human melanocytes rapidly transfer the produced melanin to kerat …
In contrast, in the human skin, typical dendritic melanocytes were hardly observed even in pigmented lesions, although supranuclear melan …
Keratinocyte-melanocyte interactions during melanosome transfer.
Seiberg M. Seiberg M. Pigment Cell Res. 2001 Aug;14(4):236-42. doi: 10.1034/j.1600-0749.2001.140402.x. Pigment Cell Res. 2001. PMID: 11549105 Review.
The epidermal-melanin unit is composed of one melanocyte and approximately 36 neighboring keratinocytes, working in synchrony to produce and distribute melanin. Melanin is synthesized in melanosomes, transferred to the dendrite tips, and translocated into ker …
The epidermal-melanin unit is composed of one melanocyte and approximately 36 neighboring keratinocytes, working in synchrony to prod …
30 results