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Page 1
Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.
GBD 2017 Causes of Death Collaborators. GBD 2017 Causes of Death Collaborators. Lancet. 2018 Nov 10;392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7. Epub 2018 Nov 8. Lancet. 2018. PMID: 30496103 Free PMC article.
BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected …
BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet th …
Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source: The Young ESUS Longitudinal Cohort Study.
Perera KS, de Sa Boasquevisque D, Rao-Melacini P, Taylor A, Cheng A, Hankey GJ, Lee S, Fabregas JM, Ameriso SF, Field TS, Arauz A, Coutts SB, Arnold M, Mikulik R, Toni D, Mandzia J, Veltkamp RC, Meseguer E, Haeusler KG, Hart RG; Young ESUS Investigators. Perera KS, et al. JAMA Neurol. 2022 May 1;79(5):450-458. doi: 10.1001/jamaneurol.2022.0048. JAMA Neurol. 2022. PMID: 35285869 Free PMC article.
IMPORTANCE: Cryptogenic strokes constitute approximately 40% of ischemic strokes in young adults, and most meet criteria for the embolic stroke of undetermined source (ESUS). ...
IMPORTANCE: Cryptogenic strokes constitute approximately 40% of ischemic strokes in young adults, and most meet criteria for the embo …
Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial.
Rosenson RS, Gaudet D, Ballantyne CM, Baum SJ, Bergeron J, Kershaw EE, Moriarty PM, Rubba P, Whitcomb DC, Banerjee P, Gewitz A, Gonzaga-Jauregui C, McGinniss J, Ponda MP, Pordy R, Zhao J, Rader DJ. Rosenson RS, et al. Nat Med. 2023 Mar;29(3):729-737. doi: 10.1038/s41591-023-02222-w. Epub 2023 Mar 6. Nat Med. 2023. PMID: 36879129 Free PMC article. Clinical Trial.
Although the primary end point of a reduction in triglycerides did not meet the prespecified significance level, the observed safety and changes in lipid and lipoprotein levels support the further evaluation of evinacumab in larger trials of patients with sHTG. ...
Although the primary end point of a reduction in triglycerides did not meet the prespecified significance level, the observed safety …
Cabozantinib for radioiodine-refractory differentiated thyroid cancer (COSMIC-311): a randomised, double-blind, placebo-controlled, phase 3 trial.
Brose MS, Robinson B, Sherman SI, Krajewska J, Lin CC, Vaisman F, Hoff AO, Hitre E, Bowles DW, Hernando J, Faoro L, Banerjee K, Oliver JW, Keam B, Capdevila J. Brose MS, et al. Lancet Oncol. 2021 Aug;22(8):1126-1138. doi: 10.1016/S1470-2045(21)00332-6. Epub 2021 Jul 5. Lancet Oncol. 2021. PMID: 34237250 Clinical Trial.
An objective response in the OITT population was achieved in ten (15%; 99% CI 5.8-29.3) of 67 patients in the cabozantinib group versus 0 (0%; 0-14.8) of 33 in the placebo (p=0.028) but did not meet the prespecified significance level (alpha=0.01). At interim analysis, the …
An objective response in the OITT population was achieved in ten (15%; 99% CI 5.8-29.3) of 67 patients in the cabozantinib group versus 0 (0 …
Acetylation in Mitochondria Dynamics and Neurodegeneration.
Waddell J, Banerjee A, Kristian T. Waddell J, et al. Cells. 2021 Nov 5;10(11):3031. doi: 10.3390/cells10113031. Cells. 2021. PMID: 34831252 Free PMC article. Review.
Mitochondria are a unique intracellular organelle due to their evolutionary origin and multifunctional role in overall cellular physiology and pathophysiology. To meet the specific spatial metabolic demands within the cell, mitochondria are actively moving, dividing, or fu …
Mitochondria are a unique intracellular organelle due to their evolutionary origin and multifunctional role in overall cellular physiology a …
Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.
James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, Roberts NLS, Sylte DO, Bertolacci GJ, Cunningham M, Henry NJ, LeGrand KE, Abdelalim A, Abdollahpour I, Abdulkader RS, Abedi A, Abegaz KH, Abosetugn AE, Abushouk AI, Adebayo OM, Adsuar JC, Advani SM, Agudelo-Botero M, Ahmad T, Ahmed MB, Ahmed R, Eddine Aichour MT, Alahdab F, Alanezi FM, Alema NM, Alemu BW, Alghnam SA, Ali BA, Ali S, Alinia C, Alipour V, Aljunid SM, Almasi-Hashiani A, Almasri NA, Altirkawi K, Abdeldayem Amer YS, Andrei CL, Ansari-Moghaddam A, T Antonio CA, Anvari D, Yaw Appiah SC, Arabloo J, Arab-Zozani M, Arefi Z, Aremu O, Ariani F, Arora A, Asaad M, Ayala Quintanilla BP, Ayano G, Ayanore MA, Azarian G, Badawi A, Badiye AD, Baig AA, Bairwa M, Bakhtiari A, Balachandran A, Banach M, Banerjee SK, Banik PC, Banstola A, Barker-Collo SL, Bärnighausen TW, Barzegar A, Bayati M, Bazargan-Hejazi S, Bedi N, Behzadifar M, Belete H, Bennett DA, Bensenor IM, Berhe K, Bhagavathula AS, Bhardwaj P, Bhat AG, Bhattacharyya K, Bhutta ZA, Bibi S, Bijani A, Boloor A, Borges G, Borschmann R, Borzì AM, Boufous S, Braithwaite D, Briko NI, Brugha T, Budhathoki SS, Car J, Cárdenas R, Carvalho F, Castaldelli-Maia JM, Castañeda-Orjue… See abstract for full author list ➔ James SL, et al. Inj Prev. 2020 Oct;26(Supp 1):i125-i153. doi: 10.1136/injuryprev-2019-043531. Epub 2020 Aug 24. Inj Prev. 2020. PMID: 32839249 Free PMC article.
The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. METHODS: In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation …
The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet the …
Catalytic promiscuity and heme-dependent redox regulation of H2S synthesis.
Banerjee R. Banerjee R. Curr Opin Chem Biol. 2017 Apr;37:115-121. doi: 10.1016/j.cbpa.2017.02.021. Epub 2017 Mar 7. Curr Opin Chem Biol. 2017. PMID: 28282633 Free PMC article. Review.
A heme-regulated switch embedded in the first enzyme in the pathway can help avert the stochastic production of cysteine versus H(2)S and control switching between metabolic tracks to meet cellular needs. This review discusses the dominant role of enzyme promiscuity in pat …
A heme-regulated switch embedded in the first enzyme in the pathway can help avert the stochastic production of cysteine versus H(2)S and co …
Far from the nuclear crowd: Cytoplasmic lncRNA and their implications in synaptic plasticity and memory.
Samaddar S, Banerjee S. Samaddar S, et al. Neurobiol Learn Mem. 2021 Nov;185:107522. doi: 10.1016/j.nlm.2021.107522. Epub 2021 Sep 20. Neurobiol Learn Mem. 2021. PMID: 34547434 Review.
We have highlighted how lncRNAs modify a functional compartment to meet the demand for input-specific control of synaptic plasticity and memory....
We have highlighted how lncRNAs modify a functional compartment to meet the demand for input-specific control of synaptic plasticity …
Current pharmaceutical design on adhesive based transdermal drug delivery systems.
Ghosh A, Banerjee S, Kaity S, Wong TW. Ghosh A, et al. Curr Pharm Des. 2015;21(20):2771-83. doi: 10.2174/1381612821666150428130215. Curr Pharm Des. 2015. PMID: 25925119 Review.
This in turn poses difficulty to design a universal formulation to meet the intended adhesiveness, drug release and drug permeation performances. ...
This in turn poses difficulty to design a universal formulation to meet the intended adhesiveness, drug release and drug permeation p …
A Materials Science Perspective of Midstream Challenges in the Utilization of Heavy Crude Oil.
Douglas LD, Rivera-Gonzalez N, Cool N, Bajpayee A, Udayakantha M, Liu GW, Anita, Banerjee S. Douglas LD, et al. ACS Omega. 2022 Jan 6;7(2):1547-1574. doi: 10.1021/acsomega.1c06399. eCollection 2022 Jan 18. ACS Omega. 2022. PMID: 35071852 Free PMC article. Review.
Unconventional deposits such as the Canadian Oil Sands in Northern Alberta contain more than one-third of the world's viscous oil reserves and are vital linchpins to meet the energy needs of rapidly industrializing populations. Heavy oil is typically recovered from subsurf …
Unconventional deposits such as the Canadian Oil Sands in Northern Alberta contain more than one-third of the world's viscous oil reserves a …
96 results