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Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome.
Noguera-Castells A, García-Prieto CA, Álvarez-Errico D, Esteller M. Noguera-Castells A, et al. Epigenetics. 2023 Dec;18(1):2185742. doi: 10.1080/15592294.2023.2185742. Epigenetics. 2023. PMID: 36871255 Free PMC article.
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. ...
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regul …
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group; Campbell PJ, Tubio JMC; PCAWG Consortium. Rodriguez-Martin B, et al. Nat Genet. 2020 Mar;52(3):306-319. doi: 10.1038/s41588-019-0562-0. Epub 2020 Feb 5. Nat Genet. 2020. PMID: 32024998 Free PMC article.
Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study.
Tarín-Vicente EJ, Alemany A, Agud-Dios M, Ubals M, Suñer C, Antón A, Arando M, Arroyo-Andrés J, Calderón-Lozano L, Casañ C, Cabrera JM, Coll P, Descalzo V, Folgueira MD, García-Pérez JN, Gil-Cruz E, González-Rodríguez B, Gutiérrez-Collar C, Hernández-Rodríguez Á, López-Roa P, de Los Ángeles Meléndez M, Montero-Menárguez J, Muñoz-Gallego I, Palencia-Pérez SI, Paredes R, Pérez-Rivilla A, Piñana M, Prat N, Ramirez A, Rivero Á, Rubio-Muñiz CA, Vall M, Acosta-Velásquez KS, Wang A, Galván-Casas C, Marks M, Ortiz-Romero PL, Mitjà O. Tarín-Vicente EJ, et al. Lancet. 2022 Aug 27;400(10353):661-669. doi: 10.1016/S0140-6736(22)01436-2. Epub 2022 Aug 8. Lancet. 2022. PMID: 35952705 Free PMC article.
Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases.
Balestri W, Sharma R, da Silva VA, Bobotis BC, Curle AJ, Kothakota V, Kalantarnia F, Hangad MV, Hoorfar M, Jones JL, Tremblay MÈ, El-Jawhari JJ, Willerth SM, Reinwald Y. Balestri W, et al. J Neuroinflammation. 2024 Jan 23;21(1):32. doi: 10.1186/s12974-024-03024-8. J Neuroinflammation. 2024. PMID: 38263227 Free PMC article. Review.
The application of 3D and organ-on-a-chip models in neurodegenerative disease research marks a prosperous step forward, providing a more realistic representation of the complex interactions within the neuroimmune system. ...
The application of 3D and organ-on-a-chip models in neurodegenerative disease research marks a prosperous step forward, providing a m …
Viral dynamics in patients with monkeypox infection: a prospective cohort study in Spain.
Suñer C, Ubals M, Tarín-Vicente EJ, Mendoza A, Alemany A, Hernández-Rodríguez Á, Casañ C, Descalzo V, Ouchi D, Marc A, Rivero À, Coll P, Oller X, Miguel Cabrera J, Vall-Mayans M, Dolores Folgueira M, Ángeles Melendez M, Agud-Dios M, Gil-Cruz E, Paris de Leon A, Ramírez Marinero A, Buhiichyk V, Galván-Casas C, Paredes R, Prat N, Sala Farre MR, Bonet-Simó JM, Farré M, Ortiz-Romero PL, Clotet B, García-Patos V, Casabona J, Guedj J, Cardona PJ, Blanco I; Movie Group; Marks M, Mitjà O. Suñer C, et al. Lancet Infect Dis. 2023 Apr;23(4):445-453. doi: 10.1016/S1473-3099(22)00794-0. Epub 2022 Dec 12. Lancet Infect Dis. 2023. PMID: 36521505 Free PMC article.
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group; Campbell PJ, Tubio JMC; PCAWG Consortium. Rodriguez-Martin B, et al. Nat Genet. 2023 Jun;55(6):1080. doi: 10.1038/s41588-023-01319-9. Nat Genet. 2023. PMID: 36944736 Free PMC article. No abstract available.
Biological basis of extensive pleiotropy between blood traits and cancer risk.
Pardo-Cea MA, Farré X, Esteve A, Palade J, Espín R, Mateo F, Alsop E, Alorda M, Blay N, Baiges A, Shabbir A, Comellas F, Gómez A, Arnan M, Teulé A, Salinas M, Berrocal L, Brunet J, Rofes P, Lázaro C, Conesa M, Rojas JJ, Velten L, Fendler W, Smyczynska U, Chowdhury D, Zeng Y, He HH, Li R, Van Keuren-Jensen K, de Cid R, Pujana MA. Pardo-Cea MA, et al. Genome Med. 2024 Feb 2;16(1):21. doi: 10.1186/s13073-024-01294-8. Genome Med. 2024. PMID: 38308367 Free PMC article.
Analysis of genomic positions, expression quantitative trait loci, enhancers, regulatory marks, functionally defined gene sets, and bulk- and single-cell expression profiles predicted the biological impact of pleiotropic variants. ...A high frequency of pleiotropic associa …
Analysis of genomic positions, expression quantitative trait loci, enhancers, regulatory marks, functionally defined gene sets, and b …
Evaluating the Accuracy of Self-Collected Swabs for the Diagnosis of Mpox.
Ubals M, Tarín-Vicente EJ, Oller X, Mendoza A, Alemany A, Hernández-Rodríguez Á, Casañ C, Rivero Á, Coll P, Cabrera JM, Vall M, Agud-Dios M, Gil-Cruz E, Paris de Leon A, Marinero AR, Folgueira MD, Meléndez MÁ, Buhiichyk V, Galván-Casas C, Paredes R, Prat N, Sala Farré MR, Bonet-Simó JM, Ortiz-Romero PL, Clotet B, Cardona PJ, Blanco I, Marks M, Suñer C, Mitjà O; Movie Group. Ubals M, et al. Clin Infect Dis. 2023 Apr 3;76(7):1311-1314. doi: 10.1093/cid/ciac889. Clin Infect Dis. 2023. PMID: 36370091
Prospective protochordate homologs of vertebrate midbrain and MHB, with some thoughts on MHB origins.
Lacalli TC. Lacalli TC. Int J Biol Sci. 2006;2(3):104-9. doi: 10.7150/ijbs.2.104. Epub 2006 May 5. Int J Biol Sci. 2006. PMID: 16763669 Free PMC article. Review.
This suggests that, irrespective of its modern function, the MHB marks the site of an organizing center of considerable antiquity. ...
This suggests that, irrespective of its modern function, the MHB marks the site of an organizing center of considerable antiquity. .. …
H4K5 Butyrylation Coexist with Acetylation during Human Spermiogenesis and Are Retained in the Mature Sperm Chromatin.
de la Iglesia A, Jauregi P, Jodar M, Barrachina F, Ded L, Mallofré C, Rodríguez-Carunchio L, Corral JM, Ballescà JL, Komrskova K, Castillo J, Oliva R. de la Iglesia A, et al. Int J Mol Sci. 2022 Oct 17;23(20):12398. doi: 10.3390/ijms232012398. Int J Mol Sci. 2022. PMID: 36293256 Free PMC article.
It has been shown that butyrylation on the same residue (H4K5bu) participates in temporal regulation of NH-NP transition in mice, delaying the bromodomain testis specific protein (BRDT)-dependent nucleosome disassembly and potentially marking retained nucleosomes. However, …
It has been shown that butyrylation on the same residue (H4K5bu) participates in temporal regulation of NH-NP transition in mice, delaying t …
19 results