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2003 1
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Page 1
Adherence monitoring in naltrexone pharmacotherapy trials: a systematic review.
Swift R, Oslin DW, Alexander M, Forman R. Swift R, et al. Among authors: alexander m. J Stud Alcohol Drugs. 2011 Nov;72(6):1012-8. doi: 10.15288/jsad.2011.72.1012. J Stud Alcohol Drugs. 2011. PMID: 22051215 Free PMC article. Review.
The "adherence-assurance score" of these trials was calculated as a function of the frequency with which "low," "moderate," or "high" confidence levels of adherence monitoring were used. Of these 22 randomized, controlled trials, only 3 (14%) met criteria for high level …
The "adherence-assurance score" of these trials was calculated as a function of the frequency with which "low," "moderate," or "high" confid …
FORCE Risk Stratification Tool for Pediatric Cardiac Rehabilitation and Fitness Programs.
Gauthier N, Reynolds L, Curran T, O'Neill J, Gauvreau K, Alexander ME. Gauthier N, et al. Among authors: alexander me. Pediatr Cardiol. 2023 Aug;44(6):1302-1310. doi: 10.1007/s00246-022-03010-y. Epub 2022 Sep 19. Pediatr Cardiol. 2023. PMID: 36121492
We piloted a system based on hemodynamic rather than anatomic factors: function, oxygen level, rhythm, complex/coronary anatomy, and elevated load (FORCE). ...The total number of fitness sessions/participant was similar across FORCE levels. It was feasible to risk s …
We piloted a system based on hemodynamic rather than anatomic factors: function, oxygen level, rhythm, complex/coronary anatomy, and …
Activity During the COVID-19 Pandemic in Children with Cardiac Rhythm Management Devices.
Przybylski R, Craig M, Lippmann M, Mah DY, Shafer KM, Gauthier NS, de Ferranti SD, Triedman JK, Alexander ME. Przybylski R, et al. Among authors: alexander me. Pediatr Cardiol. 2022 Apr;43(4):784-789. doi: 10.1007/s00246-021-02787-8. Epub 2021 Dec 1. Pediatr Cardiol. 2022. PMID: 34851446 Free PMC article.
We observed a significant decrease in device-measured physical activity from baseline (February 3-March 9), with up to a 21% decrease in physical activity during mid-March through early May. Activity levels returned to pre-pandemic levels in June. Physical activity …
We observed a significant decrease in device-measured physical activity from baseline (February 3-March 9), with up to a 21% decrease in phy …
Long-term Effects of an Evidence-based Guideline for Emergency Management of Pediatric Syncope.
Shanahan KH, Monuteaux MC, Brunson D, Guse SE, Alexander ME, Porter JJ, Neuman MI, Fine AM. Shanahan KH, et al. Among authors: alexander me. Pediatr Qual Saf. 2020 Oct 26;5(6):e361. doi: 10.1097/pq9.0000000000000361. eCollection 2020 Nov-Dec. Pediatr Qual Saf. 2020. PMID: 33134761 Free PMC article.
From the pre-EBG period to the long-term follow-up period, recommended electrocardiogram and urine pregnancy test rose significantly [level change odds ratio (95% confidence interval) 5.56 (1.73-17.91) and 3.15 (1.07-9.32), respectively]. Testing and management not recomme …
From the pre-EBG period to the long-term follow-up period, recommended electrocardiogram and urine pregnancy test rose significantly [lev …
Preoperative electrocardiograms for nonsyndromic children with hand syndactyly.
Nuzzi LC, Pike CM, Lewine EB, Cerrato FE, Alexander ME, Ferrari LR, Bae DS, Taghinia A, Waters PM, Labow BI. Nuzzi LC, et al. Among authors: alexander me. J Hand Surg Am. 2015 Mar;40(3):452-5. doi: 10.1016/j.jhsa.2014.10.053. Epub 2014 Dec 24. J Hand Surg Am. 2015. PMID: 25542431
Our study does not support routine EKG testing for children referred for syndactyly release, and we have abandoned this practice. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic IV....
Our study does not support routine EKG testing for children referred for syndactyly release, and we have abandoned this practice. TYPE OF ST …
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia.
Suragani RN, Cawley SM, Li R, Wallner S, Alexander MJ, Mulivor AW, Gardenghi S, Rivella S, Grinberg AV, Pearsall RS, Kumar R. Suragani RN, et al. Among authors: alexander mj. Blood. 2014 Jun 19;123(25):3864-72. doi: 10.1182/blood-2013-06-511238. Epub 2014 May 2. Blood. 2014. PMID: 24795345 Free PMC article.
Notably, RAP-536 treatment mitigated disease complications of IE, including iron overload, splenomegaly, and bone pathology, while reducing erythropoietin levels, improving erythrocyte morphology, and extending erythrocyte life span. ...
Notably, RAP-536 treatment mitigated disease complications of IE, including iron overload, splenomegaly, and bone pathology, while reducing …
In-hospital arrhythmia development and outcomes in pediatric patients with acute myocarditis.
Miyake CY, Teele SA, Chen L, Motonaga KS, Dubin AM, Balasubramanian S, Balise RR, Rosenthal DN, Alexander ME, Walsh EP, Mah DY. Miyake CY, et al. Among authors: alexander me. Am J Cardiol. 2014 Feb 1;113(3):535-40. doi: 10.1016/j.amjcard.2013.10.021. Epub 2013 Nov 9. Am J Cardiol. 2014. PMID: 24332245
Arrhythmias were associated with low voltages on the electrocardiogram (14 of 34, 41% vs 6 of 47, 13%; odds ratio [OR] 4.78, 95% confidence interval [CI] 1.60 to 14.31) and worse outcome (mechanical support, orthotopic heart transplant, or death; OR 7.59, 95% CI 2.61 to 22.07) bu …
Arrhythmias were associated with low voltages on the electrocardiogram (14 of 34, 41% vs 6 of 47, 13%; odds ratio [OR] 4.78, 95% confidence …
Cardiac troponin T as a screening test for myocarditis in children.
Eisenberg MA, Green-Hopkins I, Alexander ME, Chiang VW. Eisenberg MA, et al. Among authors: alexander me. Pediatr Emerg Care. 2012 Nov;28(11):1173-8. doi: 10.1097/PEC.0b013e318271736c. Pediatr Emerg Care. 2012. PMID: 23114243
CONCLUSIONS: In children without preexisting heart disease, a cTnT level of less than 0.01 ng/mL can be used to exclude myocarditis....
CONCLUSIONS: In children without preexisting heart disease, a cTnT level of less than 0.01 ng/mL can be used to exclude myocarditis.. …
Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome.
Khwaja OS, Ho E, Barnes KV, O'Leary HM, Pereira LM, Finkelstein Y, Nelson CA 3rd, Vogel-Farley V, DeGregorio G, Holm IA, Khatwa U, Kapur K, Alexander ME, Finnegan DM, Cantwell NG, Walco AC, Rappaport L, Gregas M, Fichorova RN, Shannon MW, Sur M, Kaufmann WE. Khwaja OS, et al. Among authors: alexander me. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4596-601. doi: 10.1073/pnas.1311141111. Epub 2014 Mar 12. Proc Natl Acad Sci U S A. 2014. PMID: 24623853 Free PMC article.
Mecasermin reached the CNS compartment as evidenced by the increase in cerebrospinal fluid IGF-1 levels at the end of the MAD. The drug followed nonlinear kinetics, with greater distribution in the peripheral compartment. ...
Mecasermin reached the CNS compartment as evidenced by the increase in cerebrospinal fluid IGF-1 levels at the end of the MAD. The dr …
Digital music players cause interference with interrogation telemetry for pacemakers and implantable cardioverter-defibrillators without affecting device function.
Webster G, Jordao L, Martuscello M, Mahajan T, Alexander ME, Cecchin F, Triedman JK, Walsh EP, Berul CI. Webster G, et al. Among authors: alexander me. Heart Rhythm. 2008 Apr;5(4):545-50. doi: 10.1016/j.hrthm.2008.02.033. Epub 2008 Mar 4. Heart Rhythm. 2008. PMID: 18362020 Free PMC article. Clinical Trial.
Therefore, we recommend that DMPs not be used during device interrogation, but suggest that there is reassuring counterevidence to mitigate the current high level of concern for interactions between DMPs and implantable cardiac rhythm devices....
Therefore, we recommend that DMPs not be used during device interrogation, but suggest that there is reassuring counterevidence to mitigate …
11 results