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Year Number of Results
2001 1
2002 2
2003 1
2005 1
2008 2
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2010 1
2011 1
2012 2
2013 2
2014 1
2015 4
2016 3
2017 2
2018 4
2019 2
2020 4
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2022 5
2023 1
2024 2

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45 results

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Page 1
The grass isn't always greener: The effects of cannabis on embryological development.
Friedrich J, Khatib D, Parsa K, Santopietro A, Gallicano GI. Friedrich J, et al. BMC Pharmacol Toxicol. 2016 Sep 29;17(1):45. doi: 10.1186/s40360-016-0085-6. BMC Pharmacol Toxicol. 2016. PMID: 27680736 Free PMC article. Review.
With the increasing publicity of marijuana due to recent legislation, it is pertinent that the effects of fetal exposure to the drug are assessed. ...This paper aims to demonstrate the effects of cannabis exposure on a developing embryo in order to provide a molecul …
With the increasing publicity of marijuana due to recent legislation, it is pertinent that the effects of fetal exposure to the drug …
Cannabidiol induces ERK activation and ROS production to promote autophagy and ferroptosis in glioblastoma cells.
Kim NY, Shivanne Gowda SG, Lee SG, Sethi G, Ahn KS. Kim NY, et al. Chem Biol Interact. 2024 May 1;394:110995. doi: 10.1016/j.cbi.2024.110995. Epub 2024 Apr 5. Chem Biol Interact. 2024. PMID: 38583854
Small molecule-driven ERK activation is known to induce autophagy and ferroptosis in cancer cells. Herein the effect of cannabidiol (CBD), a phytochemical derived from Cannabis sativa, on ERK-driven autophagy and ferroptosis has been demonstrated in glioblast …
Small molecule-driven ERK activation is known to induce autophagy and ferroptosis in cancer cells. Herein the effect of cannabidiol ( …
Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation.
Galve-Roperh I, Chiurchiù V, Díaz-Alonso J, Bari M, Guzmán M, Maccarrone M. Galve-Roperh I, et al. Prog Lipid Res. 2013 Oct;52(4):633-50. doi: 10.1016/j.plipres.2013.05.004. Epub 2013 Sep 25. Prog Lipid Res. 2013. PMID: 24076098 Review.
Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted the attention of human civilizations for centuries, much earlier than the discovery and characterization of their substrate of action, the endocannabinoid system (ECS). ...
Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted the attention of human civilization …
Repositioning therapy for thyroid cancer: new insights on established medications.
Kushchayeva Y, Jensen K, Burman KD, Vasko V. Kushchayeva Y, et al. Endocr Relat Cancer. 2014 May 6;21(3):R183-94. doi: 10.1530/ERC-13-0473. Print 2014 Jun. Endocr Relat Cancer. 2014. PMID: 24446492 Review.
Experimental in vitro and in vivo evidences, as well as results of clinical studies, have indicated that molecular targets for medications currently available for the treatment of mood disorders, sexually transmitted diseases, metabolic disorders, and diabetes may be active and r …
Experimental in vitro and in vivo evidences, as well as results of clinical studies, have indicated that molecular targets for medications c …
Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids.
Liu WM, Fowler DW, Dalgleish AG. Liu WM, et al. Curr Clin Pharmacol. 2010 Nov;5(4):281-7. doi: 10.2174/157488410793352049. Curr Clin Pharmacol. 2010. PMID: 20925645 Review.
Cannabinoids, the active components of the cannabis plant, have some clinical merit both as an anti-emetic and appetite stimulant in cachexic patients. ...Impressive anti-cancer activities have been reported; actions that are mediated in large part by disruptions to ubiqui …
Cannabinoids, the active components of the cannabis plant, have some clinical merit both as an anti-emetic and appetite stimulant in …
Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission.
Valjent E, Pagès C, Rogard M, Besson MJ, Maldonado R, Caboche J. Valjent E, et al. Eur J Neurosci. 2001 Jul;14(2):342-52. doi: 10.1046/j.0953-816x.2001.01652.x. Eur J Neurosci. 2001. PMID: 11553284
However, blockade of dopaminergic (DA) D1 receptors by administration of SCH 23390, prior to THC, totally prevents ERK activation in the striatum, thus demonstrating a critical involvement of DA systems in THC-induced ERK activation. ...Furthermore, THC-induced phos …
However, blockade of dopaminergic (DA) D1 receptors by administration of SCH 23390, prior to THC, totally prevents ERK activation in …
Cannabidiol activates MAPK pathway to induce apoptosis, paraptosis, and autophagy in colorectal cancer cells.
Kim NY, Mohan CD, Sethi G, Ahn KS. Kim NY, et al. J Cell Biochem. 2024 Apr;125(4):e30537. doi: 10.1002/jcb.30537. Epub 2024 Feb 15. J Cell Biochem. 2024. PMID: 38358093
Mitogen-activated protein kinase (MAPK) activation by natural compounds is known to be involved in the induction of apoptosis, paraptosis, and autophagy. Cannabidiol (CBD), a bioactive compound found in Cannabis sativa, is endowed with many pharmacological activities. We i …
Mitogen-activated protein kinase (MAPK) activation by natural compounds is known to be involved in the induction of apoptosis, paraptosis, a …
Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to delta(9)-THC and Ethanol Binge Drinking During Adolescence.
Silva-Peña D, Rivera P, Alén F, Vargas A, Rubio L, García-Marchena N, Pavón FJ, Serrano A, Rodríguez de Fonseca F, Suárez J. Silva-Peña D, et al. Front Mol Neurosci. 2019 Apr 24;12:96. doi: 10.3389/fnmol.2019.00096. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31068789 Free PMC article.
In the present study we further analyze the role of OEA in hippocampal neurogenesis, BDNF-ERK signaling, and spatial memory that are affected by alcohol. Additionally, we addressed the effects of OEA on the association of alcohol and cannabis, a frequent combination …
In the present study we further analyze the role of OEA in hippocampal neurogenesis, BDNF-ERK signaling, and spatial memory that are …
The psychoactive substance of cannabis delta9-tetrahydrocannabinol (THC) negatively regulates CFTR in airway cells.
Chang SW, Wellmerling J, Zhang X, Rayner RE, Osman W, Mertz S, Amer AO, Peeples ME, Boyaka PN, Cormet-Boyaka E. Chang SW, et al. Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1988-1994. doi: 10.1016/j.bbagen.2018.06.008. Epub 2018 Jun 19. Biochim Biophys Acta Gen Subj. 2018. PMID: 29928919
BACKGROUND: Marijuana consumption is on the rise in the US but the health benefits of cannabis smoking are controversial and the impact of cannabis components on lung homeostasis is not well-understood. ...CONCLUSIONS AND GENERAL SIGNIFICANCE: THC negatively …
BACKGROUND: Marijuana consumption is on the rise in the US but the health benefits of cannabis smoking are controversial and t …
45 results