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Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization.
Zhang S, Li W, Luan J, Srivastava A, Carnevale V, Klein ML, Sun J, Wang D, Teora SP, Rijpkema SJ, Meeldijk JD, Wilson DA. Zhang S, et al. Nat Chem. 2023 Feb;15(2):240-247. doi: 10.1038/s41557-022-01090-0. Epub 2022 Nov 21. Nat Chem. 2023. PMID: 36411361 Free PMC article.
Here, we report the adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) (PEG) host as a non-covalent binding strategy for surface functionalization. By using polycyclic aromatic hydrocarbons as the hydrophobic anchor, hydrophilic ch …
Here, we report the adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) (PEG) host as a non-covalent binding stra …
Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study.
Ravandi F, Assi R, Daver N, Benton CB, Kadia T, Thompson PA, Borthakur G, Alvarado Y, Jabbour EJ, Konopleva M, Takahashi K, Kornblau S, DiNardo CD, Estrov Z, Flores W, Basu S, Allison J, Sharma P, Pierce S, Pike A, Cortes JE, Garcia-Manero G, Kantarjian HM. Ravandi F, et al. Lancet Haematol. 2019 Sep;6(9):e480-e488. doi: 10.1016/S2352-3026(19)30114-0. Epub 2019 Aug 7. Lancet Haematol. 2019. PMID: 31400961 Free PMC article. Clinical Trial.
Six patients had seven grade 3-4 immune-related adverse events with two cases of rash, two of colitis, and one each of transaminitis, pancreatitis, and cholecystitis. 19 (43%) of 44 patients achieved a response and proceeded to allogeneic stem cell transplantation, with grade 3-4 …
Six patients had seven grade 3-4 immune-related adverse events with two cases of rash, two of colitis, and one each of transaminitis, pancre …
Peak shape modeling by Haarhoff-Van der Linde function for the determination of correct migration times: a new insight into affinity capillary electrophoresis.
Le Saux T, Varenne A, Gareil P. Le Saux T, et al. Electrophoresis. 2005 Aug;26(16):3094-104. doi: 10.1002/elps.200500029. Electrophoresis. 2005. PMID: 16041707
In this work, EMD distorted triangular peak shapes obtained in the course of host-guest complexation studies were fitted with the Haarhoff-Van der Linde function, allowing better estimation of migration time. ...
In this work, EMD distorted triangular peak shapes obtained in the course of host-guest complexation studies were fitted with the Haa …
Visible and Near-Infrared Plasmon-Mediated Molecular Release from Cucurbit[6]uril Mesoporous Gated Systems.
Marquez DT, Scaiano JC. Marquez DT, et al. Langmuir. 2016 Dec 27;32(51):13764-13770. doi: 10.1021/acs.langmuir.6b03679. Epub 2016 Dec 12. Langmuir. 2016. PMID: 27936764
The successful incorporation of a thermoresponsive gate based on a cucurbit[6]uril-hexamethylene diamine (CB6-Hex) host-guest complex conferred the system with the desired "zero" premature release. ...
The successful incorporation of a thermoresponsive gate based on a cucurbit[6]uril-hexamethylene diamine (CB6-Hex) host-guest complex …