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The role of laboratory processing in determining diagnostic conclusiveness of breast fine needle aspirations: conventional smearing versus a monolayer preparation.
Wauters CA, Kooistra B, Strobbe LJ. Wauters CA, et al. J Clin Pathol. 2009 Oct;62(10):931-4. doi: 10.1136/jcp.2009.066589. J Clin Pathol. 2009. PMID: 19783723
From 1999 to 2003, aspirate preparation was performed in the laboratory, creating a MP, using a Hettich cytocentrifuge. FNA diagnoses were categorised into inadequate (C1), benign (C2), atypical (C3), suspicious for malignancy (C4) and malignant (C5). ...CONCLUSION: Patien …
From 1999 to 2003, aspirate preparation was performed in the laboratory, creating a MP, using a Hettich cytocentrifuge. FNA diagnoses …
Single molecule tracking and analysis framework including theory-predicted parameter settings.
Kuhn T, Hettich J, Davtyan R, Gebhardt JCM. Kuhn T, et al. Sci Rep. 2021 May 4;11(1):9465. doi: 10.1038/s41598-021-88802-7. Sci Rep. 2021. PMID: 33947895 Free PMC article.
Common tracking tools often operate on single movies and require additional manual steps to analyze whole data sets or to compare different experimental conditions. ...
Common tracking tools often operate on single movies and require additional manual steps to analyze whole data sets or to compare dif …
Multi-Omics integration can be used to rescue metabolic information for some of the dark region of the Pseudomonas putida proteome.
Tavis S, Hettich RL. Tavis S, et al. BMC Genomics. 2024 Mar 11;25(1):267. doi: 10.1186/s12864-024-10082-y. BMC Genomics. 2024. PMID: 38468234 Free PMC article.
Among the predicted functions supplied by the model, we found evidence for a significant overrepresentation of nitrogen metabolism and macromolecule processing proteins. These findings were corroborated by manual analyses of selected proteins which identified, among others …
Among the predicted functions supplied by the model, we found evidence for a significant overrepresentation of nitrogen metabolism and macro …
Strain-resolved microbial community proteomics reveals simultaneous aerobic and anaerobic function during gastrointestinal tract colonization of a preterm infant.
Brooks B, Mueller RS, Young JC, Morowitz MJ, Hettich RL, Banfield JF. Brooks B, et al. Front Microbiol. 2015 Jul 1;6:654. doi: 10.3389/fmicb.2015.00654. eCollection 2015. Front Microbiol. 2015. PMID: 26191049 Free PMC article.
No prior studies have coupled strain-resolved community metagenomics to proteomics for such a purpose. Sequences were manually curated to resolve the genomes of two strains of Citrobacter that were present during the later stage of colonization. ...
No prior studies have coupled strain-resolved community metagenomics to proteomics for such a purpose. Sequences were manually curate …
Moving away from the reference genome: evaluating a peptide sequencing tagging approach for single amino acid polymorphism identifications in the genus Populus.
Abraham P, Adams RM, Tuskan GA, Hettich RL. Abraham P, et al. J Proteome Res. 2013 Aug 2;12(8):3642-51. doi: 10.1021/pr400192r. Epub 2013 Jul 23. J Proteome Res. 2013. PMID: 23795892
Using shotgun proteomics data from two genotypes of P. trichocarpa, a tag-based approach enabled the detection of 6653 unexpected sequence variants. Through manual validation, our study investigated how the most abundant chemical modification (methionine oxidation) could m …
Using shotgun proteomics data from two genotypes of P. trichocarpa, a tag-based approach enabled the detection of 6653 unexpected sequence v …
PTMSearchPlus: software tool for automated protein identification and post-translational modification characterization by integrating accurate intact protein mass and bottom-up mass spectrometric data searches.
Kertesz V, Connelly HM, Erickson BK, Hettich RL. Kertesz V, et al. Anal Chem. 2009 Oct 15;81(20):8387-95. doi: 10.1021/ac901163c. Anal Chem. 2009. PMID: 19775152
Corresponding and annotated AIPM and BU mass spectra are also displayed for visual inspection when a listed protein or a peptide is selected. These and other controls ensure that the user can manually evaluate, modify (e.g., remove obvious false positives, low quality spec …
Corresponding and annotated AIPM and BU mass spectra are also displayed for visual inspection when a listed protein or a peptide is selected …
A computerised machine for the facilitated production of intermingled skin grafts.
Hettich R, Hafemann B, Kistler D, Eren S, Mattes U, Ungethuem M. Hettich R, et al. Br J Plast Surg. 1992 Aug-Sep;45(6):421-5. doi: 10.1016/0007-1226(92)90205-c. Br J Plast Surg. 1992. PMID: 1393246
We have solved this problem by designing and constructing a computer-controlled machine, which in one operation punches holes out of strips of allogeneic donor skin and in another cuts fitting islets out of autogenous skin and transfers them into these holes. In comparison to …
We have solved this problem by designing and constructing a computer-controlled machine, which in one operation punches holes out of strips …