Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
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Jaynes JM, et al.
Sci Transl Med. 2020 Feb 12;12(530):eaax6337. doi: 10.1126/scitranslmed.aax6337.
Sci Transl Med. 2020.
PMID: 32051227
Free PMC article.
RP-182 is a synthetic 10-mer amphipathic analog of host defense peptides that selectively induces a conformational switch of the mannose receptor CD206 expressed on TAMs displaying an M2-like phenotype. ...
RP-182 is a synthetic 10-mer amphipathic analog of host defense peptides that selectively induces a conformational switch of the mannose …