Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2003 2
2005 1
2006 1
2008 1
2009 3
2010 7
2011 6
2012 13
2013 7
2014 7
2015 11
2016 7
2017 8
2018 15
2019 13
2020 10
2021 14
2022 12
2023 10
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

134 results

Results by year

Filters applied: . Clear all
Page 1
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Jin Z, Chang B, Wei Y, Yang Y, Zhang H, Liu J, Piao L, Bai L. Jin Z, et al. Biomed Pharmacother. 2022 Jul;151:113092. doi: 10.1016/j.biopha.2022.113092. Epub 2022 May 10. Biomed Pharmacother. 2022. PMID: 35550528 Free article.
Curcumin can significantly attenuate OA characteristics according to Osteoarthritis Research Society International (OARSI) and Mankin scores in OA rats. Additionally, curcumin is notably employed as an activator of mitophagy in maintaining mitochondrial homeostasis (ROS, C …
Curcumin can significantly attenuate OA characteristics according to Osteoarthritis Research Society International (OARSI) and Mankin
Non-weight-bearing exercise attenuates papain-induced knee osteoarthritis in rats via the TLR4/MyD88/NF-κB signaling pathway.
Wang K, Zhang X, Li X, Li D, Shan Z, Yao C. Wang K, et al. J Orthop Surg Res. 2023 Sep 18;18(1):695. doi: 10.1186/s13018-023-04201-w. J Orthop Surg Res. 2023. PMID: 37718444 Free PMC article.
METHODS: In this study, a papain-induced KOA model was constructed, and the pathological changes in cartilage tissue were observed by hematoxylin and eosin (H&E) staining and scored according to the Mankin scoring principle. The serum levels of interleukin (IL)-1beta, …
METHODS: In this study, a papain-induced KOA model was constructed, and the pathological changes in cartilage tissue were observed by hemato …
Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF-β-Smad2/3 signaling of chondrocytes.
Ge Y, Xu W, Chen Z, Zhang H, Zhang W, Chen J, Huang J, Du W, Tong P, Shan L, Zhou L. Ge Y, et al. Front Pharmacol. 2023 Mar 27;14:900205. doi: 10.3389/fphar.2023.900205. eCollection 2023. Front Pharmacol. 2023. PMID: 37050907 Free PMC article.
Results and Discussion: The animal data showed that PWL and TWL values, Mankin's and OARSI scorings, and the Col2 expression in cartilage were significantly improved in the NFL-treated OA rats. ...
Results and Discussion: The animal data showed that PWL and TWL values, Mankin's and OARSI scorings, and the Col2 expression i …
[Intervention effect of Youguiwan on rats with knee osteoarthritis and its mechanism].
Yan CL, An FY, Wang YF, Jin H, Zhao CB, Wang TX, Deng J, Zhang LL. Yan CL, et al. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2020 Sep;36(5):511-516. doi: 10.12047/j.cjap.5988.2020.109. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2020. PMID: 33629568 Free article. Chinese.
After intervening, articular cartilage of rats were obtained, the pathological changes were observed by using HE staining method, and Mankin score was evaluated. The expressions of OGN, ON and FBN2 in articular cartilage were detected by immunohistochemistry. The expressio …
After intervening, articular cartilage of rats were obtained, the pathological changes were observed by using HE staining method, and Man
Histological scoring systems for tissue-engineered, ex vivo and degenerative meniscus.
Longo UG, Loppini M, Romeo G, Maffulli N, Denaro V. Longo UG, et al. Knee Surg Sports Traumatol Arthrosc. 2013 Jul;21(7):1569-76. doi: 10.1007/s00167-012-2142-z. Epub 2012 Jul 26. Knee Surg Sports Traumatol Arthrosc. 2013. PMID: 22829330 Review.
Furthermore, the validity and applicability of the scoring systems were assessed. RESULTS: The Copenhaver classification and Mankin score have been modified to classify the degeneration of collagen bundles in the meniscal structure. The Pauli score seems to be a comprehens …
Furthermore, the validity and applicability of the scoring systems were assessed. RESULTS: The Copenhaver classification and Mankin s …
Clock gene Per1 regulates rat temporomandibular osteoarthritis through NF-κB pathway: an in vitro and in vivo study.
Wei JM, Tu SQ, Wang YX, Zhang S, Feng Y, Ai H, Chen Z. Wei JM, et al. J Orthop Surg Res. 2023 Oct 31;18(1):817. doi: 10.1186/s13018-023-04301-7. J Orthop Surg Res. 2023. PMID: 37907921 Free PMC article.
The thickness of cartilage in UAC group significantly reduced. The modified Mankin scores and the expression of PER1, MMP13 and P65 in cartilage of UAC group significantly increased compared with Sham group. ...
The thickness of cartilage in UAC group significantly reduced. The modified Mankin scores and the expression of PER1, MMP13 and P65 i …
Cangxitongbi capsule protects articular cartilage of the knee in rats by regulating ADAMTS-5.
Song XY, Xie WP, Zhang P, Zhao M, Bi RX. Song XY, et al. Ann Transl Med. 2020 Nov;8(22):1511. doi: 10.21037/atm-20-7011. Ann Transl Med. 2020. PMID: 33313256 Free PMC article.
After pharmacological administration for 4 weeks, knee articular cartilages were observed by hematoxylin and eosin (HE) staining and evaluated by Mankin score. Western blot and reverse transcription-polymerase chain reaction (RT-PCR) were used to detect the concentration o …
After pharmacological administration for 4 weeks, knee articular cartilages were observed by hematoxylin and eosin (HE) staining and evaluat …
Study on the Protective Effect of Platelet-Rich Plasma Combined with Injection of Pain Points Around Knee Joint on Knee Osteoarthritis and its Molecular Mechanism.
Zhao X, Zhang Q, Bu Z. Zhao X, et al. Altern Ther Health Med. 2023 Nov 17:AT9814. Online ahead of print. Altern Ther Health Med. 2023. PMID: 37971469 Free article.
RESULTS: In clinical studies, PRP can reduce patients' NRS and WOMAC scores and alleviate the progression of knee arthritis; In rat experiments, PRP reduced damage from knee arthritis and lowered Mankin's score. PRP improves tubular formation of HUVECs and the proli …
RESULTS: In clinical studies, PRP can reduce patients' NRS and WOMAC scores and alleviate the progression of knee arthritis; In rat experime …
CDK4 expression in chordoma: A potential therapeutic target.
Liu T, Shen JK, Choy E, Zhang Y, Mankin HJ, Hornicek FJ, Duan Z. Liu T, et al. J Orthop Res. 2018 Jun;36(6):1581-1589. doi: 10.1002/jor.23819. Epub 2017 Dec 22. J Orthop Res. 2018. PMID: 29194728 Free article.
134 results