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Page 1
Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP).
Butzkueven H, Kappos L, Wiendl H, Trojano M, Spelman T, Chang I, Kasliwal R, Jaitly S, Campbell N, Ho PR, Licata S; Tysabri Observational Program (TOP) Investigators. Butzkueven H, et al. J Neurol Neurosurg Psychiatry. 2020 Jun;91(6):660-668. doi: 10.1136/jnnp-2019-322326. Epub 2020 Mar 31. J Neurol Neurosurg Psychiatry. 2020. PMID: 32234967 Free PMC article.
OBJECTIVE: The Tysabri Observational Programme (TOP), which began >10 years ago, is an open-label, multinational, prospective observational study evaluating the long-term safety and effectiveness of natalizumab in relapsing-remitting multiple sclerosis patients. ...
OBJECTIVE: The Tysabri Observational Programme (TOP), which began >10 years ago, is an open-label, multinational, prospective observation …
Current techniques for AB0-incompatible living donor liver transplantation.
Rummler S, Bauschke A, Bärthel E, Jütte H, Maier K, Ziehm P, Malessa C, Settmacher U. Rummler S, et al. World J Transplant. 2016 Sep 24;6(3):548-55. doi: 10.5500/wjt.v6.i3.548. World J Transplant. 2016. PMID: 27683633 Free PMC article. Review.
For a long time, it was considered medical malpractice to neglect the blood group system during transplantation. ...
For a long time, it was considered medical malpractice to neglect the blood group system during transplantation. ...
Which factors affect the long-term survival of patients with hepatocellular carcinoma UICC stage IV?
Bauschke A, Altendorf-Hofmann A, Malessa C, Schüle S, Zanow J, Settmacher U. Bauschke A, et al. J Cancer Res Clin Oncol. 2016 Dec;142(12):2593-2601. doi: 10.1007/s00432-016-2260-y. Epub 2016 Sep 15. J Cancer Res Clin Oncol. 2016. PMID: 27630023
After tumor resection, patients lived longer than those who underwent local or systemic treatment only (p = 0.003 or p = 0.001, respectively). In the univariate survival analysis, the stage IV patients' long-term survival was decreased statistically significantly through e …
After tumor resection, patients lived longer than those who underwent local or systemic treatment only (p = 0.003 or p = 0.001, respectively …
Current Challenges in the Post-Transplant Care of Liver Transplant Recipients in Germany.
Herzer K, Sterneck M, Welker MW, Nadalin S, Kirchner G, Braun F, Malessa C, Herber A, Pratschke J, Weiss KH, Jaeckel E, Tacke F. Herzer K, et al. J Clin Med. 2020 Nov 5;9(11):3570. doi: 10.3390/jcm9113570. J Clin Med. 2020. PMID: 33167567 Free PMC article.
Improving long-term patient and graft survival after liver transplantation (LT) remains a major challenge. ...Further discussions and studies are required to define optimal structure and content of post-LT care systems, aiming at improving the long-term outcomes of …
Improving long-term patient and graft survival after liver transplantation (LT) remains a major challenge. ...Further discussions and …
Segmentation of Radar-Recorded Heart Sound Signals Using Bidirectional LSTM Networks.
Shi K, Weigel R, Koelpin A, Schellenberger S, Weber L, Wiedemann JP, Michler F, Steigleder T, Malessa A, Lurz F, Ostgathe C. Shi K, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:6677-6680. doi: 10.1109/EMBC.2019.8857863. Annu Int Conf IEEE Eng Med Biol Soc. 2019. PMID: 31947373
However, practice is needed to assess the findings correctly. Furthermore, stethoscopes do not allow for long-term monitoring of a patient. Recently, radar technology has shown the ability to perform continuous touchless and thereby burden-free heart sound measurements. In …
However, practice is needed to assess the findings correctly. Furthermore, stethoscopes do not allow for long-term monitoring of a pa …
Contactless analysis of heart rate variability during cold pressor test using radar interferometry and bidirectional LSTM networks.
Shi K, Steigleder T, Schellenberger S, Michler F, Malessa A, Lurz F, Rohleder N, Ostgathe C, Weigel R, Koelpin A. Shi K, et al. Sci Rep. 2021 Feb 4;11(1):3025. doi: 10.1038/s41598-021-81101-1. Sci Rep. 2021. PMID: 33542260 Free PMC article.
Our proposed approach is capable to perform contactless and convenient HRV monitoring and is therefore suitable for long-term recordings in clinical environments and home-care scenarios....
Our proposed approach is capable to perform contactless and convenient HRV monitoring and is therefore suitable for long-term recordi …
FDG PET/CT to Detect Incidental Findings in Patients With Hepatocellular Carcinoma-Additional Benefit for Patients Considered for Liver Transplantation?
Winkens T, Rudakoff W, Rauchfuss F, Malessa C, Settmacher U, Freesmeyer M. Winkens T, et al. Clin Nucl Med. 2021 Jul 1;46(7):532-539. doi: 10.1097/RLU.0000000000003576. Clin Nucl Med. 2021. PMID: 33661197
As compared with localized imaging approaches (MRI, ultrasonography), FDG PET/CT not only focuses on the liver, but covers a long field of view from the base of the skull to the thighs, visualizing pathologic findings not related to HCC. ...
As compared with localized imaging approaches (MRI, ultrasonography), FDG PET/CT not only focuses on the liver, but covers a long fie …
Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting.
Trojano M, Butzkueven H, Kappos L, Wiendl H, Spelman T, Pellegrini F, Chen Y, Dong Q, Koendgen H, Belachew S; Tysabri® Observational Program (TOP) Investigators. Trojano M, et al. Mult Scler Relat Disord. 2018 Aug;24:11-19. doi: 10.1016/j.msard.2018.04.020. Epub 2018 May 2. Mult Scler Relat Disord. 2018. PMID: 29860197 Free article.
Alcoholism, peripheral neuropathy (PNP) and cardiovascular autonomic neuropathy (CAN).
Agelink MW, Malessa R, Weisser U, Lemmer W, Zeit T, Majewski T, Klieser E. Agelink MW, et al. J Neurol Sci. 1998 Dec 11;161(2):135-42. doi: 10.1016/s0022-510x(98)00266-4. J Neurol Sci. 1998. PMID: 9879694
In contrast to diabetic autonomic neuropathy, cardiovascular autonomic neuropathy (CAN) in long-term alcoholics has been studied rarely. Using both standardized bedside tests and computer-assisted analysis of heart rate variability (HRV), we prospectively compared autonomi …
In contrast to diabetic autonomic neuropathy, cardiovascular autonomic neuropathy (CAN) in long-term alcoholics has been studied rare …
Validity of eleven prognostic scores with respect to intra- and extrahepatic recurrence of hepatocellular carcinoma after liver transplantation.
Bauschke A, Altendorf-Hofmann A, Kissler H, Koch A, Malessa C, Settmacher U. Bauschke A, et al. J Cancer Res Clin Oncol. 2017 Dec;143(12):2595-2605. doi: 10.1007/s00432-017-2507-2. Epub 2017 Aug 28. J Cancer Res Clin Oncol. 2017. PMID: 28849266
METHODS: Data of 147 consecutive patients transplanted at our department between 1996 and 2014 were analyzed and staged for morphological and functional scores of underlying liver disease. For long-term follow-up, we analyzed intrahepatic (within the liver distant metastas …
METHODS: Data of 147 consecutive patients transplanted at our department between 1996 and 2014 were analyzed and staged for morphological an …
14 results